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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Seasonal changes of photosynthetic assimilation of Norway spruce under the impact of enhanced UV-B radiation显示文摘 | Sprtova M Marek M V Nedbal L | 1999 | Plant Science1999，142，： | 1 |
| 3 | Synthetic peptides that mimic the binding site of Horseshae crab antipopolysaaccharide factor显示文摘 | Kerry M Paul L | 1994 | J Infect Dis1994，170，11： | 1 |
| 4 | Antioxidant potential, paraoxo- nase 1, ceruloplasmin activity and C-reactive protein concentra- tion in diabetic retinopathy显示文摘 | Nowak M Wielkoszynski T Marek B Kos-Kudta B Swieto- chowska E Sieminska L | 2010 | Clin Exp Med2010，10，3： | 1 |
| 5 | On the pharmacology of teaseed-saponins of a saponin mixture from thea sinensis L显示文摘 | Vogel G Marek M L Oertner R | 1998 | Phytotherapy Research1998，18，11： | 1 |
| 6 | Expression and genome organization of resistance gene analogs in soy bean 显示文摘 | Graham M A Marek L F Lohnes D | 2000 | Genome2000，43，： | 1 |
| 7 | Resistance gene analogs are conserved and clustered in soybean 显示文摘 | Kanazin V M Marek L F Shoemaker R C | 1996 | Proc Natl Acad Sei USA1996，93，11： | 1 |
| 8 | Immune programming显示文摘 | Peter M Adriel L Marek R | 2006 | Information Sciences2006，176，8： | 1 |
| 9 | A Meta-analysis of the Effects of Oral Zinc in the Treatment of Acute and Persistent Diarrhea显示文摘 | Marek Lukacik M D Ronald L Thomas | 2008 | Ped-iateics2008，121，2： | 1 |
| 10 | Das therapeutische wirksarne Prinzip der Rosskastanie ( Aesculus hippocastanum) 显示文摘 | Lorenz D Marek M L | 1960 | Arzneim - Forseh1960，10，： | 1 |
| 11 | Parasitic Meloidogyne and mutualistic Acremonium coenophialum increase chitinase in tall fescue显示文摘 | Marek S M Niblack T L | 1992 | Journal of Chemical Ecology1992，18，： | 1 |
| 12 | On the pharmacology of teaseed-saponins of a saponin mixture from Thea sinensis L显示文摘 | Vogel G Marek M L Oertner R | 1968 | Arzneimittelforschung1968，18，11： | 1 |
| 13 | Electrochemical and Raman spectroscopic studies of the influence of chlorinated solvents on the corrosion behaviour of iron in borate buffer and in simulated groundwater显示文摘 | PASCALE M L JEDRAL W MAREK S O | 2000 | Corrosion science2000，42，： | 1 |
| 14 | Molecular markers useful for detecting resistance to brown stem rot in soybean显示文摘 | Klos K L E Paz M M Marek LF | 2000 | Crop Science2000，40，： | 1 |
| 15 | Biological therapy in inflammatory rheumatic diseases: issues in Central and Eastern European countries显示文摘 | Márta Péntek Gyula Poór Piotr Wiland Martina Olejárová Marek Brzosko Catalin Codreanu Nóra Brodszky László Gulácsi | 2014 | The European Journal of Health Economics2014，，1： | 1 |
| 16 | The mechanism of corro- sion of palladium-silver binary alloys in artificial saliva 显示文摘 | Joska L Marek M Leitner J | 2005 | Biomaterials2005，26，14： | 1 |
| 17 | On the pharmacology of teasee-aponins of a saponin mixture from thea sinensis 显示文摘 | VOGEL G MAREK M L OERTNER R | 1998 | Phyto - therapy Research1998，18，11： | 1 |
| 18 | Promotion of EFL Student Mo- tivation, Confidence, and Satisfaction Via a Learning Spiral, Peer- Scaffolding, and CMC显示文摘 | Wu W Marek M & Yen L | 2012 | International Journal of Computer-Assisted Language Learning and Teaching2012，3，2： | 1 |
| 19 | Potential Riskof Arsenic and Antimony Accumulation by MedicinalPlants Naturally Growing on Old Mining Sites 显示文摘 | Marek V L' ubomir J Peter M | 2013 | Water Air Soil Pollut2013，224，5： | 1 |
| 20 | Acute effects of static and proprioceptive neuromuscular facilitation stretching on muscle strength and power output显示文摘 | MAREK S M CRAMER J T FINCHER A L | 2005 | J Athl Train2005，40，2： | 1 |
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