5篇
您的检索式：作者名="MARISA R F"
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| 1 | Synthesis,structural characterization and biological activity of p-fluorobenzaldehyde thiosemicarbazones and of a nickel complex显示文摘 | MARISA B F SILVIA C GIOIA R | 2000 | J Inorg Biochem2000，81，： | 1 |
| 2 | Comparative effect of chrysotile leaching in nitric,sulfuric and oxalic acids at room temperature显示文摘 | MARISA R F JAVIER H | 2013 | Chemical Geology2013，352，： | 1 |
| 3 | Comparative effect of chrysotile leach- ing in nitric, sulfuric and oxalic acids at room temperature显示文摘 | MARISA R F JAVIER H | 2013 | Chemical Geology2013，，352： | 1 |
| 4 | Thermophysical Characterization of Ionic Liquids Able to Dissolve显示文摘 | Mara G F Ana R T Marisa A | 2011 | Journal of Chemical and Emgineering Data2011，56，12： | 1 |
| 5 | Twelve-month efficacy and safety of the conversion to everolimus in maintenance heart transplant recipients显示文摘AIM: To determine the clinical reasons for conversion to everolimus(EVL) and long-term outcomes in heart transplant(HT) recipients.METHODS: A retrospective 12-mo study has been carried out in 14 Spanish centres to assess the efficacy and safety of conversion to EVL in maintenance HT recipients.RESULTS: Two hundred and twenty-two patients were included(mean age: 53 ± 10.5 years; mean time from HT: 8.1 ± 4.5 years). The most common reasons for conversion were nephrotoxicity(30%), chronic allograft vasculopathy(20%) and neoplasms(17%). The doses and mean levels of EVL at baseline(conversion to EVL) and after one year were 1.3 ± 0.3 and 1.2 ± 0.6 mg/d and 6.4 ± 3.4 and 5.6 ± 2.5 ng/mL, respectively. The percentage of patients receiving calcineurin inhibitors(CNIs) at baseline and on the final visit was 95% and 65%, respectively. The doses and mean levels of CNIs decreased between baseline and month 12 from 142.2 ± 51.6 to 98.0 ± 39.4 mg/d(P < 0.001) and from 126.1 ± 50.9 to 89.2 ± 47.7 ng/mL(P < 0.001), respectively, for cyclosporine, and from 2.9 ± 1.8 to 2.6 ± 1.9 mg/d and from 8.3 ± 4.0 to 6.5 ± 2.7 ng/mL(P = 0.011) for tacrolimus. In the subgroup of patients converted because of nephrotoxicity, creatinine clearance increased from 34.9 ± 10.1 to 40.4 ± 14.4 mL/min(P < 0.001). There were 37 episodes of acute rejection in 24 patients(11%). The most frequent adverse events were oedemas(12%), infections(9%) and gastrointestinal problems(6%). EVL was suspended in 44 patients(20%). Since the database was closed at the end of the study, no further followup data is available.CONCLUSION: Conversion to EVL in maintenance HT recipients allowed minimisation or suspension of the CNIs, with improved kidney function in the patients with nephrotoxicity, after 12 mo. | Nicolás Manito Juan F Delgado María G Crespo-Leiro José María Arizón Javier Segovia Francisco González-Vílchez Sònia Mirabet Ernesto Lage Domingo Pascual-Figal Beatriz Díaz Jesús Palomo Gregorio Rábago Marisa Sanz Teresa Blasco Eulàlia Roig | 2015 | World Journal of Transplantation2015，5，4： | 0 |
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