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| 1 | Effects of Gibberellic Acid on Primary Terpenoids and △^9 -Tetrahydrocannabinol in Cannabis sativa at Flowering Stage显示文摘Plants synthesize an astonishing diversity of isoprenoids,some of which play essential roles in photosynthesis,respiration,and the regulation of growth and development.Two independent pathways for the biosynthesis of isoprenoid precursors coexist within the plant cell: the cytosolic mevalonic acid (MVA) pathway and the plastidial methylerythritol phosphate (MEP) pathway.However,little is known about the effects of plant hormones on the regulation of these pathways.In the present study we investigated the effect of gibberellic acid (GA3) on changes in the amounts of many produced terpenoids and the activity of the key enzymes,1-deoxy-D-xylulose 5-phosphate synthase (DXS) and 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR),in these pathways.Our results showed GA3 caused a decrease in DXS activity in both sexes that it was accompanied by a decrease in chlorophylls,carotenoids and 9-tetrahydrocannabinol (THC) contents and an increase in α-tocopherol content.The treated plants with GA3 showed an increase in HMGR activity.This increase in HMGR activity was followed by accumulation of stigmasterol and β-sitosterol in male and female plants and campestrol in male plants.The pattern of the changes in the amounts of sterols was exactly similar to the changes in the HMGR activity.These data suggest that GA3 can probably influence the MEP and MVA pathways oppositely,with stimulatory and inhibitory effects on the produced primary terpenoids in MVA and DXS pathways,respectively. | Hakimeh Mansouri Zahra Asrar Mitra Mehrabani | 2009 | Journal of Integrative Plant Biology2009，51，6： | 8 |
| 2 | Risk factors of gastroesophageal reflux disease in Shiraz,southern Iran显示文摘AIM: To determine the prevalence and symptoms of gastroesophageal reflux disease (GERD) in a healthy general population in relation to demographic,lifestyle and health-seeking behaviors in Shiraz,southern Iran. METHODS: A total of 1978 subjects aged > 35 years who referred to Gastroenterohepatology Research Center and who completed a questionnaire consisting of 27 questions for GERD in relation to demographic,lifestyle and health-seeking behaviors were included in this study for a period of five months. The validity and reliability of the questionnaire were determined. RESULTS: The prevalence of GERD was 15.4%,which was higher in females (17.3%),in rural areas (19.8%),and in illiterate subjects (21.5%) and those with a mean age of 50.25 years. The prevalence was significantly lower in subjects having fried food (14.8%),and fruit and vegetables (14.6%). More symptoms were noticed in subjects consuming pickles (22.1%),taking aspirin (21%) and in subjects with psychological distresses (27.2%) and headaches (22%). The correlation was statistically significant between GERD and halitosis (18.3%),dyspepsia (30.6%),anxiety (19.5%),nightmares (23.9%) and restlessness (18.5%). Their health seeking behavior showed that there was a significant restriction of diet (20%),consumption of herbal medicine (19%),using over-the-counter drugs (29.9%) and consulting with physicians (24.8%). Presence of GERD symptoms was also significantly related to a previous family history of the disease (22.3%).CONCLUSION: GERD is more common in females,rural and illiterate subjects and correlated with consumption of pickles,occurrence of headache,psychological distress,dyspepsia,halitosis,anxiety,nightmare and restlessness,and a family history of GERD and aspirin intake,but the correlation was negative with consumption of fat and fiber intake. | Mehdi Saberi-Firoozi Farnaz Khademolhosseini Maryam Yousefi Davood Mehrabani Najaf Zare Seyed Taghi Heydari | 2007 | World Journal of Gastroenterology2007，13，41： | 7 |
| 3 | Hepatitis B virus genotypes in southwest Iran: Molecular, serological and clinical outcomes显示文摘AIM: To investigate the associations of hepatitis B virus (HBV) genotype with HBeAg and anti-HBe status, alanine aminotransferase (ALT) levels and HBV-DNA detection in different groups of HBV-infected patients in southwest Iran. METHODS: A total of 89 HBsAg-positive serum samples were collected from the same number of patients. All sera were then investigated to determine HBV DNA and serological markers. For all the polymerase chain reaction (PCR)-positive samples, biochemical, histopathological assays and genotyping were also performed. RESULTS: Genotype D was the only type of HBV foundin different clinical forms of acute and chronic infections. There was a high prevalence of HBeAg-negative HBV- infected patients with chronic hepatitis (52.7%). Out of 55 patients with chronic hepatitis, seven (12.7%) were diagnosed with cirrhosis. A significant association between the presence of anti-HBe antibody and an increase in ALT level, among either HBeAg-negative (P = 0.01) or HBeAg-positive (P = 0.026) patients, was demonstrated. No significant differences were observed between the clinical outcomes of HBeAg-positive and -negative individuals (P = 0.24). CONCLUSION: Genotype D has been recognized as the only type of HBV found in different clinical forms of HBV infections, including cirrhosis, among the residents of southwest Iran. Anti-HBe possibly plays a role in disease progression in some patients with chronic hepatitis, at least for a period of disease. | Anahita Mojiri Abbas Behzad-Behbahani Mehdei Saberifirozi Maryam Ardabili Mahmood Beheshti Marjan Rahsaz Mehrdad Banihashemi Negar Azarpira Bita Geramizadeh Baharak Khadang Afsaneh Moaddeb Mojgan Ghaedi Tahereh Heidari Ardeshir Torab Alireza Salah Saeid Amirzadeh Zahra Jowkar Davood Mehrabani Samad Amini-Bavil-Olyaee Mohammad Ali Dehyadegari | 2008 | World Journal of Gastroenterology2008，14，10： | 4 |
| 4 | Bioleaching of sphalerite sample from Kooshk leadizinc tailing dam 显示文摘 | Mehrabani J V Shafaei S Z Noaparast M | 2013 | Transactions of Nonferrous Metals Society of Chian2013，23，12： | 1 |
| 5 | The MDA-180 coagulation analyzer: a laboratory evaluation显示文摘 | Mehrabani P A Coombs R | 1997 | Pathology1997，29，： | 1 |
| 6 | Tissue engineered scaffolds in regenerative medicine 显示文摘 | Hosseinkhani M Mehrabani D Karimfar MH | 2014 | World J Plast Surg2014，3，1： | 1 |
| 7 | Effects of Probiotics on the Recurrence of Bacterial Vaginosis: A Review显示文摘 | Aziz Homayouni Parvin Bastani Somayeh Ziyadi Sakineh Mohammad-Alizadeh-Charandabi Morad Ghalibaf Amir Mohammad Mortazavian Elnaz Vaghef Mehrabany | 2014 | Journal of Lower Genital Tract Disease2014，，1： | 1 |
| 8 | Beneficial effects of a high-protein, low-glycemic-load hypocaloric diet in overweight and obese women with polycystic ovary syndrome:a randomized controlled intervention study 显示文摘 | Mehrabani HH Salehpour S Amiri Z | 2012 | J Am Coll Nutr2012，31，2： | 1 |
| 9 | Cervical Infection with Herpes simplex Virus, Chlamydia trachomatis, and Neisseria gonorrhoeae among symptomatic women, Dubai, UAE:A Molecular approach显示文摘 | Mehrabani D Behzadi MA Azizi S | 2014 | Interdiscip Perspeet Infect Dis2014，14，4： | 1 |
| 10 | Effect of aque- ous extract of Elaeagnus angustifolia fruit on experimental cutane- ous wound healing in rats 显示文摘 | Mehrabani N M Pasalar P Kamalinejad M | 2012 | Acta Med Iran2012，50，9： | 1 |
| 11 | Prevalence of stom- ach cancer in Shiraz, Southern Iran 显示文摘 | Mehrabani D Hosseini SV Rezaianzadeh A | 2013 | J Res Med Sci2013，18，4： | 1 |
| 12 | Beneficial effects of a high-protein, low-glycemic-load hypocaloric diet in overweight and obese women with polycystic ovary syndrome: a randomized con- trolled intervention study显示文摘 | Mehrabani HH Salehpour S Amiri Z | 2012 | J Am Coil Nutr2012，31，2： | 1 |
| 13 | Prevalence and risk factors of gastroesophageal reflux disease in Qashqai migrating nomads, southern Iran显示文摘AIM: To investigate the prevalence and risk factors of gastroesophageal re? ux disease (GERD) symptoms in Qashqai migrating nomads with a different life style in Fars province, southern Iran. METHODS: In summer 2006, 748 Qashqai migrating nomads aged 25 years or more were enrolled using a multiple-stage stratified cluster random sampling method. A questionnaire consisting of demographic characteristics, lifestyle and GERD symptoms (heartburn, regurgitation, chest pain, dysphagia, hoarseness and cough) as completed for each subject. RESULTS: The questionnaire was completed in 717 subjects. The prevalence rate of GERD, defined as reflux occurring at least one time per week in the preceding year, was 33% (237 subjects). The prevalence was higher in older individuals (36.0% vs 28.9%, P < 0.05) and in those with other gastrointestinal complaints (51.0% vs 27.8%, P < 0.001), but not different in obese and non-obese subjects. It was also higher in those consuming fruitsand vegetables more than once a week (36.2% vs 17.3%, P < 0.001). GERD had a positive correlation with smoking (42.1% vs 27.8%, P < 0.001), but a negative relation with non-alcoholic beverages. The association between GERD and non-steroidal antiinflammatory drugs (NSAIDs) consumption was also signifi cant (40.2% vs 25.4%, P < 0.001). CONCLUSION: The prevalence of GERD (33%) is very high in Qashqai migrating nomads which may be due to a lower socioeconomic and educational level of these people and difference in the life style. Older age, frequent consumption of fruits and vegetables, smoking and NSAIDs are risk factors for GERD in this population. | Ahmad Mostaghni Davood Mehrabani Farnaz Khademolhosseini Seyed Jalil Masoumi Fariba Moradi Najaf Zare Mehdi Saberi-Firoozi | 2009 | World Journal of Gastroenterology2009，15，8： | 1 |
| 14 | Do probioties act more efficiently in foods than in supplements显示文摘 | Aziz Homayoni Rad Elnaz Vaghef Mehrabany Beitullah All- poor | 2012 | Nutrition2012，28，78： | 1 |
| 15 | Study of antiseizure effects of matricaria recutita extract in mice 显示文摘 | Heidari M R Dadollahi Z Mehrabani M | 2009 | Annals of the New York Academy of Science2009，1171，： | 1 |
| 16 | Process optimization and modeling of sphalerite flotation from a low-grade Zn-Pb using response surface methodology 显示文摘 | MEHRABANI J V NOAPARAST M MOUSAVI S M DEHGHAN R GHORBANI A | 2010 | Separation & Purification Technology2010，27，： | 1 |
| 17 | Depression of pyrite in the flotation of high pyrite low-grade lead-zinc ore using Aeidithiobaeillus ferrooxidans 显示文摘 | Mehrabani J V Noaparast M Mousavi S M Dehghan R Rasooli E Hajizadeh H | 2010 | Minerals Engineer- ing2010，23，1： | 1 |
| 18 | Active immunization using exotoxin A confers protection against Pseduomonas aeruginosa infection in a mouse burn model显示文摘 | Manafi A Kohanteb J Mehrabani A | 2009 | ISMC Microbiol2009，9，： | 1 |
| 19 | Echocardiographic finding in beta-thalassemia intermedia and major:absence of pulmonary hypertension following hydroxyurea treatment in betathalassemia intermedia显示文摘 | Karimi M Borzouee M Mehrabani A | | 0，，3： | 1 |
| 20 | Pepsinogen I and II, Gastrin and Cag A Serum Levels in Shiraz 显示文摘 | Shamsdin SA Saberifiroozi M Mehrabani D | 2011 | Middle East J Dig Dis2011，3，2： | 1 |
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