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| 1 | 源于近端股骨间充质干细胞免疫抑制作用的研究显示文摘目的探讨源于成人近端股骨的间充质干细胞(MSC)是否具有免疫抑制功能,为临床移植物抗宿主病的防治寻找理想的细胞储备库。方法从全髋关节置换术患者的近端股骨中分离并培养MSC,将不同数量的细胞直接或以Transwell法加入混合淋巴细胞反应(MLR)中,检测MSC对外周血淋巴细胞(PBL)增殖水平的影响。以ELISA法及抗体中和法探讨细胞因子TGFβ1在MSC免疫调节中的作用。结果3×103、1×104、3×104、1×105个源于近端股骨的MSC对PBL增殖的抑制率分别为62%±18%、38%±4%、31%±16%、28%±12%,与采自髂骨骨髓穿刺物MSC的抑制作用相比差异无统计学意义(均P>0.05),后者对PBL的增殖抑制率为58%±12%、37%±8%、28%±6%、27%±6%;以0.2μm的微孔膜对MSC与MLR进行分隔,3×104及1×104个MSC对PBL的增殖抑制率为36%±8%和53%±12%;在ELISA实验中,MSC单独培养,MSC与MLR直接接触,或经Transwell共培养的这3种上清中转化生长因子(TGF)β1的表达水平差异无统计学意义,加入浓度递增的TGFβ1抗体不能逆转MSC对PBL增殖的抑制作用。结论源于近端股骨的MSC具有一定的免疫抑制功能,除TGFβ1外其他可溶性因子可能介导这一作用。 | 张翼鷟 Loic Fouillard Alain Chapel Morad Bensidhoum Christelle Mazurier Aish Nasef Sandrine Bouchet Manuel Lopez Dominique Thierry Norbert Cclaucle Gorin 达万明 | 2005 | 中华医学杂志2005,85,39: | 11 |
| 2 | Support effects on the chemical property and catalytic activity of Co-Mo HDS catalyst in sulfur recovery显示文摘Effects of carbon nanotubes (CNT) and alumina (γ-Al2O3) supports on the catalytic activities of hydrodesulfurization (HDS) process over CoMo catalyst have been studied. XRD results indicated that the main active phases in CNT and γ-Al2O3 supported Co-Mo catalysts are MoO2 and MoO3, respectively. The TPR results reveal that the reduction peak temperatures of the active species on CNT supported Co-Mo catalyst is lower than those on alumina supported Co-Mo catalyst, indicating that the CNT supports favor the reduction of active species. Catalytic evaluation results displayed that the sulfur content in the reaction products on the CNT supported Co-Mo catalyst is lower than that on the alumina supported Co-Mo catalyst if the HDS reaction was carried out at a temperature above 583 K. | Ali Nakhaei Pour Ali Morad Rashidi Kherolah Jafari Jozani Ali Mohajeri Payman Khorami | 2010 | Journal of Natural Gas Chemistry2010,19,1: | 7 |
| 3 | SMFs-supported Pd nanocatalysts in selective acetylene hydrogenation:Pore structure-dependent deactivation mechanism显示文摘In the present study,CNFs,ZnO and Al2O3 were deposited on the SMFs panels to investigate the deactivation mechanism of Pd-based catalysts in selective acetylene hydrogenation reaction.The examined supports were characterized by SEM,NH3-TPD and N2adsorption-desorption isotherms to indicate their intrinsic characteristics.Furthermore,in order to understand the mechanism of deactivation,the resulted green oil was characterized using FTIR and SIM DIS.FTIR results confirmed the presence of more unsaturated constituents and then,more branched hydrocarbons formed upon the reaction over alumina-supported catalyst in comparison with the ones supported on CNFs and ZnO,which in turn,could block the pores mouths.Besides the limited hydrogen transfer,N2 adsorption-desorption isotherms results supported that the lowest pore diameters of Al2O3/SMFs close to the surface led to fast deactivation,compared with the other catalysts,especially at higher temperatures. | Elaheh Esmaeili Ali Morad Rashidi Yadollah Mortazavi Abbas Ali Khodadadi Mehdi Rashidzadeh | 2013 | Journal of Energy Chemistry2013,22,5: | 5 |
| 4 | Application of reliability-centered maintenance for productivity improvement of open pit mining equipment:Case study of Sungun Copper Mine显示文摘Equipment plays an important role in open pit mining industry and its cost competence at efficient operation and maintenance techniques centered on reliability can lead to significant cost reduction.The application of optimal maintenance process was investigated for minimizing the equipment breakdowns and downtimes in Sungun Copper Mine.It results in the improved efficiency and productivity of the equipment and lowered expenses as well as the increased profit margin.The field operating data of 10 trucks are used to estimate the failure and maintenance profile for each component,and modeling and simulation are accomplished by using reliability block diagram method.Trend analysis was then conducted to select proper probabilistic model for maintenance profile.Then reliability of the system was evaluated and importance of each component was computed by weighted importance measure method.This analysis led to identify the items with critical impact on availability of overall equipment in order to prioritize improvement decisions.Later,the availability of trucks was evaluated using Monte Carlo simulation and it is revealed that the uptime of the trucks is around 11000 h at 12000 operation hours.Finally,uncertainty analysis was performed to account for the uncertainty sources in data and models. | Amin Moniri Morad Mohammad Pourgol-Mohammad Javad Sattarvand | 2014 | Journal of Central South University2014,21,6: | 5 |
| 5 | Optimization of biliary drainage in inoperable distal malignant strictures显示文摘BACKGROUND Given most patients with distal malignant biliary obstruction present in the nonresectable stage,palliative endoscopic biliary drainage with fully covered metal stent(FCMS)or uncovered metal stent(UCMS)is the only available measure to improve patients’quality of life.Half covered metal stent(HCMS)has been recently introduced commercially.The adverse effects and stent function between FCMS and UCMS have been extensively discussed.AIM To study the duration of stent patency of HCMS and compare it with FCMS and UCMS to optimize biliary drainage in inoperable patients with distal malignant obstruction.Secondary aims in our study included evaluation of patients’survival and the rates of adverse events for each type of stent.METHODS We studied 210 patients and randomized them into three equal groups;HCMS,FCMS and UCMS were inserted endoscopically.RESULTS Stent occlusion occurred in(18.6%,17.1%and 15.7%in HCMS,FCMS and UCMS groups,respectively,P=0.9).Stent migration occurred only in patients with FCMS(8.6%of patients).Cholangitis and cholecystitis occurred in 11.4%and 5.7%of patients,respectively,in FCMS.Tumor growth occurred only in 10 cases among patients with UCMS after a median of 140 d,sludge occurred in nine,seven and one patients in HCMS,FCMS and UCMS,respectively(P=0.04).CONCLUSION Given the prolonged stent functioning time,the use of HCMS is preferred over the use of UCMS and FCMS for optimizing biliary drainage in patients with distal malignant biliary obstruction. | Esam Elshimi Wesam Morad Omar Elshaarawy Ahmed Attia | 2020 | World Journal of Gastrointestinal Endoscopy2020,12,9: | 5 |
| 6 | 利用铁、铜和硫掺杂TiO_(2)有效光催化转化甲酸显示文摘采用简单的溶胶-凝胶法在TiO_(2)中复合加入铜离子或铁离子和硫酸离子,并研究其甲酸光催化转化效果。通过X射线衍射(XRD)、N_(2)物理吸附(BET比表面积测量)、扫描和透射电子显微镜(SEM和TEM)、UV-Vis漫反射光谱(DRS)和X射线光电子能谱(XPS)对不同光催化剂的结构和形貌进行表征,以确定材料的理化性能与其对甲酸氧化的光催化效率之间的关系。结果显示,添加不同金属离子将导致催化剂之间的重要差异。硫酸化TiO_(2)/Cu(1%Cu)具有最佳的光催化效果,仅在5 min内就可获得100%的甲酸转化率。通过复合添加铜离子和硫酸可使催化剂获得良好的物理化学特性,使其在光催化反应中表现出优越的性能。 | ZOUHEIR Morad TANJI Karim NAVIO Jose Antonio HIDALGO María Carmen JARAMILLO-PAEZ Cesar Augusto KHERBECHE Abdelhak | 2022 | Journal of Central South University2022,29,11: | 3 |
| 7 | Treatment of hepatitis C virus genotype 4 with peginterferon alfa-2a: Impact of bilharziasis and fibrosis stage显示文摘AIM: To evaluate pegylated interferon alpha2a (PegIFN- α2a) in Egyptian patients with HCV genotype 4, and the impact of pretreatment viral load, co-existent bilharziasis and histological liver changes on response rate. METHODS: A total of 73 na?ve patients (61 with history of bilharziasis) with compensated chronic HCV genotype 4 were enrolled into: group A (38 patients) who received 180 mg PegIFN-alpha2a subcutaneously once weekly for a year and group B (35 patients) received IFN alpha-2a 3 MU 3 times weekly. Ribavirin was added to each regimen at a dose of 1200 mg. Patients were followed for 72 wk and sustained response was assessed. RESULTS: Significant improvement in both end of treatment response (ETR) (P < 0.002) and sustained response (SR) (P < 0.05) was noted with pegylated interferon, where ETR was achieved in 29 (76.3%) and 14 patients (40%) in both groups respectively, and 25 patients in group A (65.8%) and 9 (25.7%) in group B could retain negative viraemia by the end of follow up period. Sustained virological response (SVR) showed a significant negative correlation with age and positive correlation with pretreatment inflammation in patients receiving PegIFN. Viral clearance after 3 mo of therapy was associated with high incidence of ETR and SR (P < 0.001), but without significant difference between both forms of interferon. Significant improvement in response was achieved in patients with high grade fibrosis (grade 3 and 4) with PegIFN-α2a, where SR was seen in 5 out of 13 patients in group A, but none in group B. There was no significant difference in response betweenbilharzial and non-bilharzial patients in both groups. In terms of safety and tolerability, neutropenia was the predominant side effect; both drugs were comparable. CONCLUSION: PegIFN-α2a combined with ribavirin results in improvement in sustained response in HCV genotype 4, irrespective of history of bilharzial infestation. | MF Derbala SR Al Kaabi NZ El Dweik F Pasic MT Butt R Yakoob A Al-Marri AM Amer N Morad A Bener | 2006 | World Journal of Gastroenterology2006,12,35: | 3 |
| 8 | The effects of irrigation methods with effluent and irrigation scheduling on water use efficiency and corn yields in an arid region显示文摘 | Ali Morad Hassanli Mohammad Ali Ebrahimizadeh Simon Beecham | 2008 | Agricultural Water Management2008,,1: | 2 |
| 9 | Pupillography as an objective indicator of fatigue显示文摘 | Morad Y Lemberg H Yofe N | 2000 | Curr Eye Res2000,21,1: | 1 |
| 10 | Treatment of ocular tissues exposed to nitrogen mustard:beneficial effect of zinc desferrioxaminc combined with steroids显示文摘 | MORAD Y BANIN E AVERBUKH E | 2005 | Invest Ophthalmol Vis Sci2005,46,5: | 1 |
| 11 | The effect of communication and synchronization on Amdahl's law in multicore systems显示文摘 | YAVITS L MORAD A and GINOSAR R | 2014 | Parallel Computing2014,40,1: | 1 |
| 12 | Distribution of diagenetic alterations in fluvial, deltaic, and shallow marine sandstones within a sequence stratigraphic framework:Evidence from the Mullaghmore Formation ( Carboniferous), NW Ireland 显示文摘 | Ketzer J M Morad S Evans R et a/ | 2002 | Journal of Sedimentary Research2002,72,6: | 1 |
| 13 | The impact of diagenesis on the heterogeneity of sandstone reservoirs: A review of the role of depositional facies and sequence stratigraphy显示文摘 | Morad S Khalid A R Ketzer J M | 2010 | AAPG Bulletin2010,94,8: | 1 |
| 14 | A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates显示文摘 | Mitra R Morad M | 1985 | Am J Physiol Heart Circ Physiol1985,249,: | 1 |
| 15 | The impact of diagenesis on the heterogeneity of sandstone reservoirs : A review of the role of depositional facies and sequence stratigraphy 显示文摘 | Morad S Khalid Ramadan Ketzer J M | 2010 | AAPG Bulletin2010,94,8: | 1 |
| 16 | Diagenesis and reservoir quality evolution of fluvial sandstones during progressive burial and uplift : evi- dence from the Upper Jurassic Boipeba Member, Recrncavo basin, Northeastern Brazil显示文摘 | Salem A M Morad S Mato L F | 2000 | AAPG Bulletin2000,84,7: | 1 |
| 17 | Corrosion inhibi- tion of carbon-steels by propargyhriphenyl phosphonium bromide in H2SO4 solution 显示文摘 | Wahdan M H Hermas A A Morad M S | 2002 | Materials Chemistry and Physics2002,76,2: | 1 |
| 18 | Effects of Probiotics on the Recurrence of Bacterial Vaginosis: A Review显示文摘 | Aziz Homayouni Parvin Bastani Somayeh Ziyadi Sakineh Mohammad-Alizadeh-Charandabi Morad Ghalibaf Amir Mohammad Mortazavian Elnaz Vaghef Mehrabany | 2014 | Journal of Lower Genital Tract Disease2014,,1: | 1 |
| 19 | Diagenesis and reservoir quality evolution of palaeocene deep-water,marine sandstones,the Shetland-Faroes Basin,British continental shelf显示文摘 | Mansurbeg H Morad S Salem A Marfil R El-ghali M A K Nystuen J P Caja M A Amorosi A Garcia D A Iglesia La | 2008 | Marine and Petroleum Geology2008,25,: | 1 |
| 20 | 显示文摘 | Nasser HZ | 2000 | Toxicol Appl Pharm2000,166,1: | 1 |