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| 1 | Loss of microRNAs in thymus perturbs invariant NKT cell development and function显示文摘microRNAs(miRNAs)are small noncoding RNAs that mediate RNA interference to suppress protein expression at the translational level.Accumulated evidence indicates that miRNAs play critical roles in various biological processes and disease development,including autoimmune diseases.Invariant natural killer T(iNKT)cells are an unusual CD1d-restricted subset of thymus-derived T cells that are potent regulators of diverse immune responses.Our previous studies with the mouse model of bone marrow-specific Dicer deletion suggest the involvement of Dicer-dependent miRNAs in the development and function of iNKT cells.In the present study,to further dissect the functional levels of Dicer-dependent miRNAs in regulating iNKT cell development,we generated a mouse model with the Dicer deletion in the thymus.Our data indicate that lack of miRNAs following the deletion of Dicer in the thymus severely interrupted the development and maturation of iNKT cells in the thymus and significantly decreased the number of iNKT cells in the peripheral immune organs.miRNA-deficient peripheral iNKT cells display profound defects in activation and cytokine production upon a-galactosylceramide(a-GalCer)stimulation.Our results demonstrate a critical role of the miRNA-dependent pathway in the thymus in the regulation of iNKT cell development and function. | Kook-Heon Seo Li Zhou Dongmei Meng Jianrui Xu Zhong Dong Qing-Sheng Mi | 2010 | Cellular & Molecular Immunology2010，7，6： | 9 |
| 2 | Highly efficient solution-processed CZTSSe solar cells based on a convenient sodium-incorporated post-treatment method显示文摘In CZTSSe solar cells,a simple sodium-incorporation post-treatment method toward solution-processed Cu2Zn Sn S4precursor films is presented in this work.An ultrathin NaCl film is deposited on Cu2Zn Sn S4precursor films by spin-coating NaCl solution.In subsequent selenization process,the introduction of Na Cl is found to be benefacial for the formation of Cu2-xSe,which can further facilitate the element transportation,leading to dense and smooth CZTSSe films with large grains and less impurity Cu2Sn(S,Se)3phase.SIMS depth profiles confirm the gradient distribution of the sodium element in Na-doped absorbers.Photoluminescence spectra show that the introduction of appropriate sodium into the absorber can inhibit the band tail states.As high as 11.18% of power conversion efficiency(PCE)is achieved for the device treated with 5 mg mL^-1 NaCl solution,and an average efficiency of Na-doped devices is 10.71%,13%higher than that of the control groups(9.45%).Besides,the depletion width and the charge recombination lifetime can also have regular variation with sodium treatment.This work offers an easy modification method for high-quality Na-doped CZTSSe films and high-performance devices,in the meantime,it can also help to further understand the effects of sodium in CZTSSe solar cells. | Biwen Duan Linbao Guo Qing Yu Jiangjian Shi Huijue Wu Yanhong Luo Dongmei Li Sixin Wu Zhi Zheng Qingbo Meng | 2020 | Journal of Energy Chemistry2020，29，1： | 8 |
| 3 | Inorganic–organic halide perovskites for new photovoltaic technology显示文摘Perovskite solar cells(PSCs) have received worldwide attention due to excellent power-to-electricity conversion efficiency(PCE). Currently, a PCE record of as high as 22.1% has been achieved, comparative to those of copper indium gallium selenide and Cd Te solar cells. However, there are still some critical issues to solve, especially the stability issue at the current state, in order to promote PSC commercialization. In this respect, various device architectures and the working principle are briefly introduced. Then, key features of inorganic–organic hybrid perovskites and related film deposition methods are discussed.Typically, experimental and theoretical efforts to reveal the physical issues of the device are emphasized as well as the cell stability. Finally, a short summary, challenge and prospect are given. | Dongmei Li Jiangjian Shi Yuzhuan Xu Yanhong Luo Huijue Wu Qingbo Meng | 2018 | National Science Review2018，5，4： | 6 |
| 4 | Perovskite thin-film solar cell: excitation in photovoltaic science显示文摘As a new member of thin-film solar cells,the perovskite solar cells have inspired a new research hot in new photoelectric materials and devices,and have given a new energy to the photovoltaic science.Currently,various device structures,including mesoporous and planar,with and without hole transport material have been developed.In this review,much focus has been addressed to the deposition of high-quality perovskite films,structural optimization,and interface engineering as well as the understanding of the charge generation,transport,and recombination mechanisms of the devices.Furthermore,cost,stability,and environment issues of the cell are also discussed for commercial application. | Junyan Xiao Jiangjian Shi Dongmei Li Qingbo Meng | 2015 | Science China Chemistry2015，58，2： | 6 |
| 5 | Comparative pharmacokinetics of tetramethylpyrazine phosphate in rat plasma and extracellular fluid of brain after intranasal,intragastric and intravenous administration显示文摘The purpose of this study was to compare the pharmacokinetic profiles of tetramethylpyrazine phosphate(TMPP)in plasma and extracellular fluid of the cerebral cortex of rats via three delivery routes:intranasal(i.n.),intragastric(i.g.)and intravenous(i.v.)administration.After i.n.,i.g.and i.v.administration of a single-dose at 10 mg/kg,cerebral cortex dialysates and plasma samples drawn from the carotid artery were collected at timed intervals.The concentration of TMPP in the samples was analyzed by HPLC.The area under the concentration-time curve(AUC)and the ratio of the AUCbrain to the AUCplasma(drug targeting efficiency,DTE)was calculated to evaluate the brain targeting efficiency of the drug via these different routes of administration.After i.n.administration,TMPP was rapidly absorbed to reach its peak plasma concentration within 5 min and showed a delayed uptake into cerebral cortex(t_(max)=15 min).The ratio of the AUCbrain dialysates value between i.n.route and i.v.injection was 0.68,which was greater than that obtained after i.g.administration(0.43).The systemic bioavailability obtained with i.n.administration was greater than that obtained by the i.g.route(86.33%vs.50.39%),whereas the DTE of the nasal route was 78.89%,close to that of oral administration(85.69%).These results indicate that TMPP is rapidly absorbed from the nasal mucosa into the systemic circulation,and then crosses the blood-brain barrier(BBB)to reach the cerebral cortex.Intranasal administration of TMPP could be a promising alternative to intravenous and oral approaches. | Dongmei Meng Haoyang Lu Shanshan Huang Minyan Wei Pingtian Ding Xianglin Xiao Yuehong Xu Chuanbin Wu | 2014 | Acta Pharmaceutica Sinica B2014，4，1： | 5 |
| 6 | Cardiomyocyte-like differentiation of human bone marrow mesenchymal stem cells after exposure to 5-azacytidine in vitro显示文摘Objective To investigate the potential of adult mesenchymal stem cells (MSCs) derived from human bone marrow to undergo cardiomyogenic differentiation after exposure to 5-azacytidine (5-aza) in vitro. Methods A small bone marrow aspirate was taken from the iliac crest of human volunteers, and hMSCs were isolated by 1.073g/mL Percoll and propagated in the right cell culturing medium as previously described. The phenotypes of hMSCs were characterized with the use of flow cytometry. The hMSCs were cultured in cell culture medium (as control) and medium mixed with 5-aza for cellular differentiation. We examined by immunohistochemistry at 21 days the inducement of desmin, cardiac-specific cardiac troponin I (cTnI), GATA 4 and connexin-43 respectively. Results The hMSCs are fibroblast-like morphology and express CD44+ CD29+ CD90+ / CD34- CD45- CD31- CD11a. After 5-aza treatment, 20-30% hMSCs connected with adjoining cells and coalesced into myotube structures after 14days. Twenty-one days after 5-aza treatment, immunofluorescence showed that some cells expressed desmin,GATA4, cTnI and connexin-43 in 5,10 μmol/L 5-aza groups, but no cardiac specific protein was found in neither 3μmol/L 5-aza group nor in the control group. The ratio of cTnI positively stained cells in 10 μmol/L group was higher than that in 5 μmol/L group (65.3 ± 4.7% vs 48.2 ± 5.4%, P < 0.05). Electron microscopy revealed that myofilaments were formed. The induced cells expressed cardiac-myosin heavy chain (MyHC) gene by reverse transcription-polymerase chain reaction (RT-PCR). Conclusions Theses findings suggest that hMSCs from adult bone marrow can be differentiated into cardiac-like muscle cells with 5-aza inducement in vitro and the differentiation is in line with the 5-aza concentration. (J Geriatr Cardiol 2004;1(2) :101-107. ) | Feng CAO Lili NIU Ling MENG Lianxu ZHAO Dongmei Wang Ming ZHENG Cixian BAI Guoliang JIA Xuetao PEI | 2004 | Journal of Geriatric Cardiology2004，1，2： | 5 |
| 7 | A New 6D Magnetic Localization Technique for Wireless Capsule Endoscope Based on a Rectangle Magnet显示文摘 | YANG Wan'an HU Chao Max Q.H. Meng DAI Houde CHEN Dongmei | 2010 | Chinese Journal of Electronics2010，19，2： | 3 |
| 8 | Low-Carbon and Nanosheathed ZnCo_(2)O_(4) Spheroids with Porous Architecture for Boosted Lithium Storage Properties显示文摘Multielectronic reaction electrode materials for high energy density lithium-ion batteries(LIBs)are severely hindered by their inherent sluggish kinetics and large volume variations,leading to rapid capacity fade.Here,a simple method is developed to construct low-carbon and nanosheathed ZnCo_(2)O_(4) porous spheroids(ZCO@C-5).In this micro/nanostructure,an ultrathin amorphous carbon layer(∼2 nm in thickness)is distributed all over the primary nanosized ZCO particles(∼20 nm in diameter),which fnally self-assembles into porous core(ZCO)-shell(carbon)micron spheroids.Te nanoencapsulation and macro/mesoporous architecture can not only provide facile electrolyte penetration and rapid ion/electron transfer but also better alleviate volumetric expansion efect to avoid pulverization of ZCO@C-5 spheroids during repeat charge/discharge processes.As expected,the three-dimensional porous ZCO@C-5 composites exhibit high reversible capacity of 1240 mAh g^(−1) cycle at 500 mA g^(−1),as well as excellent long-term cycling stability and rate capability.Te low-carbon and nanoencapsulation strategy in this study is simple and efective,exhibiting great potential for high-performance LIBs. | Yudi Mo Junchen Liu Shuanjin Wang Min Xiao Shan Ren Dongmei Han Yuezhong Meng | 2019 | Research2019，，1： | 3 |
| 9 | Recent progress in perovskite solar cells:material science显示文摘Perovskite solar cells represent a promising third-generation photovoltaic technology with low fabrication cost and high power conversion efficiency.In light of the rapid development of perovskite materials and devices,a systematic survey on the latest advancements covering a broad range of related work is urgently needed.This review summarizes the recent major advances in the research of perovskite solar cells from a material science perspective.The discussed topics include the devices based on different type of perovskites(organic-inorganic hybrid,all-inorganic,and lead-free perovskite and perovskite quantum dots),the properties of perovskite defects,different type of charge transport materials(organic,polymeric,and inorganic hole transport materials and inorganic and organic electron transport materials),counter electrodes,and interfacial materials used to improve the efficiency and stability of devices.Most discussions focus on the key progresses reported within the recent five years.Meanwhile,the major issues limiting the production of perovskite solar cells and the prospects for the future development of related materials are discussed. | Jiang-Yang Shao Dongmei Li Jiangjian Shi Chuang Ma Yousheng Wang Xiaomin Liu Xianyuan Jiang Mengmeng Hao Luozheng Zhang Chang Liu Yiting Jiang Zhenhan Wang Yu-Wu Zhong Shengzhong(Frank)Liu Yaohua Mai Yongsheng Liu Yixin Zhao Zhijun Ning Lianzhou Wang Baomin Xu Lei Meng Zuqiang Bian Ziyi Ge Xiaowei Zhan Jingbi You Yongfang Li Qingbo Meng | 2023 | Science China Chemistry2023，66，1： | 3 |
| 10 | Methylammonium cation deficient surface for enhanced binding stability at TiO2/CH3NH3PbI3 interface显示文摘在 perovskite 太阳能电池的异质接面接口在提高他们的光电的性质和稳定性起一个重要作用。到日期为止,在 TiO 2/CH3 NH 3 PbI 3 异质接面接口没清楚地被调查。这里,我们检验了 TiO 2/CH3 NH 3 PbI 3 接口并且发现重原子层在如此的接口存在,它被归因于 methylammonium (麻省) 的空缺阳离子组。进一步,第一原则的计算结果建议麻省阳离子缺乏的表面结构为在 TiO 2 和 CH 3 NH 3 提高接口稳定性的 PbI 3 。我们的研究对进一步理解详细接口原子安排有用并且在 perovskite 太阳能电池为界面的修正提供参考书。 | Xin Xu Kai Li Zhenzhong Yang Jiangjian Shi Dongmei Li Lin Gu Zhijian Wu Qingbo Meng | 2017 | Nano Research2017，10，2： | 2 |
| 11 | Electrolytes in solid-state dye-sensitized nanocrystalline solar cells显示文摘在这篇论文,结构和敏化染料的 nanocrystalline 太阳能电池(DSSC ) 的操作原则被讨论。电解质能被划分成三种类型:液体电解质,伪固体电解质和稳固的电解质。基于我们的组的相关学习,我们主要总结了伪固体电解质和稳固的电解质的研究进步在固态 DSSC。 | AN Hongli XUE Bofei LI Dongmei MENG Qingbo GUO Lin | 2006 | Progress in Natural Science:Materials International2006，16，7： | 2 |
| 12 | Recent Progress of Counter Electrodes in Nanocrystalline Dye-sensitized Solar Cells显示文摘敏化染料的太阳能电池(DSC ) 在于有 nanoparticulated 半导体, sensitizers,电解质和相反的电极(CE ) 的几 differentmaterials:photoanodes 的联合。每材料为 CE 的主要功能是把电子转移到氧化还原作用电解质和 regenerate 碘化物离子的太阳能 intoelectricity.The 的变换执行特定的任务。GE 的工作主要集中于运动表演的研究和传统的 CE 的稳定性改进 DSC 的全面效率,寻求新奇设计概念或新材料。在这评论,发展和研究不同 CE 材料和他们的电气化学的表演进行,并且这些问题被讨论。 | Kexin LI Zhexun YU Yanhong LUO Dongmei LI Qingbo MENG | 2007 | Journal of Materials Science & Technology2007，23，5： | 2 |
| 13 | Magnetic resonance imaging for prostate cancer clinical application显示文摘As prostate cancer is a biologically heterogeneous disease for which a variety of treatment options are available, the major objective of prostate cancer imaging is to achieve more precise disease characterization. In clinical practice, magnetic resonance imaging (MRI) is one of the imaging tools for the evaluation of prostate cancer, the fusion of MRI or dynamic contrast-enhanced MRI (DCE-MRI) with magnetic resonance spectroscopic imaging (MRSI) is improving the evaluation of cancer location, size, and extent, while providing an indication of tumor aggressiveness. This review summarizes the role of MRI in the application of prostate cancer and describes molecular MRI techniques (including MRSI and DCE-MRI) for aiding prostate cancer management. | Bing Li Yong Du Hanfeng Yang Yayong Huang Jun Meng Dongmei Xiao | 2013 | Chinese Journal of Cancer Research2013，25，2： | 2 |
| 14 | Plasma oxidized lipoprotein(a) and its immune complexes are present in newborns andchildren显示文摘 | Junjun Wang Dongmei Niu Yang Meng | 2009 | Clinica Chimica Acta2009，407，9： | 1 |
| 15 | Towards optimization of materials for dye-sensitized solar cells 显示文摘 | Luo Yanhong Li Dongmei Meng Qingbo | 2009 | Advanced Materials2009，21，45： | 1 |
| 16 | Steroid receptor coactivator-1:The central intermediator linking multiple signals and functions in the brain and spinal cord显示文摘The effects of steroid hormones are believed to be mediated by their nuclear receptors(NRs).The p160 coactivator family,including steroid receptor coactivator-1(SRC-1),2 and 3,has been shown to physically interact with NRs to enhance their transactivational activities.Among which SRC-1 has been predominantly localized in the central nervous system including brain and spinal cord.It is not only localized in neurons but also detectable in neuroglial cells(mainly localized in the nuclei but also detectable in the extra-nuclear components).Although the expression of SRC-1 is regulated by many steroids,it is also regulated by some non-steroidal factors such as injury,sound and light.Functionally,SRC-1 has been implied in normal function such as development and ageing,learning and memory,central regulation on reproductive behaviors,motor and food intake.Pathologically,SRC-1 may play a role in the regulation of neuropsychiatric disorders(including stress,depression,anxiety,and autism spectrum disorder),metabolite homeostasis and obesity as well as tumorigenesis.Under most conditions,the related mechanisms are far from elucidation;although it may regulate spatial memory through Rictor/mTORC2-actin polymerization related synaptic plasticity.Several inhibitors and stimulator of SRC-1 have shown anti-cancer potentials,but whether these small molecules could be used to modulate ageing and central disorder related neuropathology remain unclear.Therefore,to elucidate when and how SRC-1 is turned on and off under different stimuli is very interesting and great challenge for neuroscientists. | Zhaoyou Meng Xiaoya Wang Dongmei Zhang Zhen Lan Xiaoxia Cai Chen Bian Jiqiang Zhang | 2022 | Genes & Diseases2022，9，5： | 1 |
| 17 | Sodium-doped carbon nitride nanotubes for efficient visible light-driven hydrogen production显示文摘做钠的碳氮化物 nanotubes (Na x -CNNTs) 被一个绿、简单的二拍子的圆舞方法准备并且在第一次切开的 photocatalytic 水里适用。印射的传播电子显微镜学(TEM ) 元素和大小证实的 X 光检查光电子光谱学(XPS ) 那钠成功地在碳氮化物被介绍 nanotubes (CNNT ) ,和 graphitic 碳氮化物的内在的结构(g-C 3 N 4) 也在产品被维持。而且, CNNT 的多孔的结构导致相对大的特定的表面区域。 Photocatalytic 测试显示多孔的管状的结构和 Na +做罐头 synergistically 在可见的光下面提高氢进化率(> 420 nm )照耀面对牺牲的代理人,象 143 摩尔一样高导致氢进化率?猯'T￣????????????????????敭整?景琠敨愠汬祯?眠楨档椠?桴?慣敳漠?桴??慇愠汬祯挠湡戠?硥汰楡敮?祢琠敨攠'諡?景朠污楬浵映潲?桴? | Longshuai Zhang Ning Ding Muneaki Hashimoto Koudai Iwasaki Noriyasu Chikamori Kazuya Nakata Yuzhuan Xu Jiangjian Shi Huijue Wu Yanhong Luo Dongmei Li Akira Fujishima Qingbo Meng | 2018 | Nano Research2018，11，4： | 1 |
| 18 | A repeated interdiffusion method for efficient planar formamidinium perovskite solar cells显示文摘A repeated interdiffusion method is described for phase-stable and high-quality(FA,MA)PbI_3 film. The crystallization and growth of the perovskite films can be well controlled by adjusting the reactant concentrations.With this method, dense, smooth perovskite films with large crystals have been obtained. Finally, a PCE of 16.5% as well as a steady-state efficiency of 16.3% is achieved in the planar perovskite solar cell. | Huiyin Zhang Jiangjian Shi Juan Dong Xin Xu Yanhong Luo Dongmei Li Qingbo Meng | 2015 | Journal of Energy Chemistry2015，24，6： | 1 |
| 19 | Synthesis of sulfonated poly(fluorenyl ether thioether ketone)s with bulky-block structure and its application in vanadium redox flow battery显示文摘 | Chen Dongyang Wang Shuanjin Xiao Min Han Dongmei Meng Yuezhong | | 0，，： | 1 |
| 20 | Efficient CHzNHzPbl3 perovskite solar cells with 2TPA- n-DP hole-transporting layers显示文摘 | Lifeng Zhu Junyan Xiao Jiangjian Shi Junjie Wang Songtao Lv Yuzhuan Xu Yanhong Luo YinXiao Shirong Wang Qingbo Meng Xianggao Li Dongmei Li | 2015 | Nano Research2015，8，4： | 1 |
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