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| 1 | Identification of QTLs and Validation of qCd-2 Associated with Grain Cadmium Concentrations in Rice显示文摘Cadmium(Cd) is one of heavy metals harmful to human health. As rice is the main staple food in Asia and Cd is easily contaminated in rice, the molecular regulation of Cd accumulation should be explored. In this study, a recombinant inbred population derived from Xiang 743/Katy was grown in Cd-polluted fields and used to map the quantitative trait loci(QTLs) for Cd accumulation in rice grains. We identified seven QTLs distributed on chromosomes 2, 3, 6, 7, 8 and 10. These QTLs displayed phenotypic variances of 58.50% and 40.59% in 2014 and 2015, respectively. Two QTLs, qCd-2 and qCd-7, were identified in both the two years. qCd-2 was detected on the interval of RM250–RM207 on chromosome 2, with an LOD of 2.51 and a phenotypic contribution of 13.75% in 2014, and an LOD of 3.35 and a phenotypic contribution of 14.16% in 2015. qCd-7 co-localized with the cloned qCdT7 on chromosome 7 and may represent the correct candidate. The other five QTLs were detected only in one year. To further confirm the effects of qCd-2, a residual heterozygous line designated as RHL945, with a heterozygous interval of RM263–RM207 on chromosome 2, was selected from the recombinant inbred population and used to develop an F2 population consisting of 155 individual plants. By incorporating further simple sequence repeat markers into the segmental linkage map of the target region, qCd-2 was delimited in the interval of RM5404–RM3774, with an LOD value of 4.38 and a phenotypic contribution of 15.52%. These results reflected the genetic regulation of grain Cd in rice and paved the way for the future cloning of qCd-2. | LIU Wenqiang PAN Xiaowu LI Yongchao DUAN Yonghong MIN Jun LIU Sanxiong LIU Licheng SHENG Xinnian LI Xiaoxiang | 2019 | Rice science2019，26，1： | 6 |
| 2 | Immunosenescence and age-related viral diseases显示文摘Immunosenescence is described as a decline in the normal functioning of the immune system associated with physiologic ageing.Immunosenescence contributes to reduced efficacy to vaccination and increased susceptibility to infectious diseases in the elderly.Extensive studies of laboratory animal models of ageing or donor lymphocyte analysis have identified changes in immunity caused by the ageing process.Most of these studies have identified phenotypic and functional changes in innate and adaptive immunity.However,it is unclear which of these defects are critical for impaired immune defense against infection.This review describes the changes that occur in innate and adaptive immunity with ageing and some age-related viral diseases where defects in a key component of immunity contribute to the high mortality rate in mouse models of ageing. | MA YongChao FANG Min | 2013 | Science China(Life Sciences)2013，56，5： | 2 |
| 3 | OPTIMIZING DESIGN OF MECHANICAL SELF-CENTERING DEVICE FOR SUSPENSION HEIGHT显示文摘Firstly,in view of the respective defects of existing self-centering devices for vehicle suspension height,the design scheme of the proposed mechanical self-centering device for suspension height is described.Taking the rear suspension of a certain light bus as a research example,the structures and parameters of the novel device are designed and ascertained.Then,the road excitation models,the performance evaluation indexes and the half-vehicle model are built,the simulation outputs of time and frequency domain are obtained with the road excitations of random and pulse by using MATLAB/Simulink sofiware.So the main characteristics of the self-centering suspension are presented preliminarily.Finally,a multi-objective parameter design optimization model for the self-centering device is built by weighted sum approach,and optimal solution is obtained by adopting complex approach.The relevant choosing-type parameters for self-centering device components are deduced by using discrete variable optimal method,and the optimal results are verified and analyzed. So the performance potentials of the self-centering device are exerted fully in condition of ensuring overall suspension performances. | CAO Min ZHANG Yongchao YU Fan | 2008 | Chinese Journal of Mechanical Engineering2008，21，6： | 2 |
| 4 | Assessing remotely sensed and reanalysis products in characterizing surface soil moisture in the Mongolian Plateau显示文摘Soil moisture(SM)plays a crucial role in the dynamics of coupled atmosphere,water,energy,and carbon cycles.In this study,the spatiotemporal distribution and variations of SM in the Mongolian Plateau were investigated for the period of 1982-2018 based on four gridded SM datasets.Taking the observed SM from 33 monitoring stations as a reference,the reliability of these four gridded products was validated,and the three-cornered hat(TCH)method was also applied to evaluate their uncertainties.Major results indicated that all these four products underestimated the SM in this region at different levels.The ERA-Interim SM performed much better than other three products,with a higher R of 0.53 and lower ubRMSE of 0.0378 m^(3)·m^(−3).Except for ECV,the surface SM exhibited a decreasing trend at−0.0004 to−0.0008 m^(3)·m^(−3)/decade in the warm season(from April to October)over the past 37 years.The greatest decreases in SM occurred in the summer season.Precipitation change plays a more important role in explaining the variations of SM than temperature reported by partial correlation analysis.The results of this study will benefit our understanding of the climate change effects and the protection of the ecological systems in this region. | Min Luo Chula Sa Fanhao Meng Yongchao Duan Tie Liu Yuhai Bao | 2021 | International Journal of Digital Earth2021，14，10： | 2 |
| 5 | The chloroplast-localized protein LTA1 regulates tiller angle and yield of rice显示文摘Plant architecture strongly influences rice grain yield.We report the cloning and characterization of the LTA1 gene,which simultaneously controls tiller angle and yield of rice.LTA1 encodes a chloroplastlocalized protein with a conserved YbaB DNA-binding domain,and is highly expressed in photosynthetic tissues including leaves and leaf sheaths.Disrupting the function of LTA1 leads to large tiller angle and yield reduction of rice.LTA1 affects the gravity response by mediating the distribution of endogenous auxin,thereby regulating the tiller angle.An lta1 mutant showed abnormal chloroplast development and decreased chlorophyll content and photosynthetic rate,in turn leading to reduction of rice yield.Our findings shed light on the genetic basis of tiller angle and provide a potential gene resource for the improvement of plant architecture and rice yield. | Xiaowu Pan Yongchao Li Haiwen Zhang Wenqiang Liu Zheng Dong Licheng Liu Sanxiong Liu Xinnian Sheng Jun Min Rongfeng Huang Xiaoxiang Li | 2022 | The Crop Journal2022，10，4： | 1 |
| 6 | A New High-Yielding Two-line Hybrid Rice Variety-Peiliang You 981显示文摘Peiliang You 981(also called 98 Guangzhi 1 orPeiliang You Guangzhi 1)is a late-season two-lineindica hybrid rice variety with high yield and latematurity. Pei’ai 64S is the female parent and R981(Guang 1) is the male parent of Peiliang You 981. Thehybrid showed its characters of high and stable yieldand wide adaptability in the variety trials anddemonstration production in the recent years,and itwas released in March 2002 by Hunan Crop VarietiesRelease Committee.Grain | Min Jun, Li Yongchao, Zhang Liguang, and Huang HaimingHunan Rice Research Institute, Changsha 410125, China | 2002 | Hunan Agricultural Science & Technology Newsletter2002，3，3： | 0 |
| 7 | Dynamic Task Offloading for Digital Twin-Empowered Mobile Edge Computing via Deep Reinforcement Learning显示文摘Limited by battery and computing re-sources,the computing-intensive tasks generated by Internet of Things(IoT)devices cannot be processed all by themselves.Mobile edge computing(MEC)is a suitable solution for this problem,and the gener-ated tasks can be offloaded from IoT devices to MEC.In this paper,we study the problem of dynamic task offloading for digital twin-empowered MEC.Digital twin techniques are applied to provide information of environment and share the training data of agent de-ployed on IoT devices.We formulate the task offload-ing problem with the goal of maximizing the energy efficiency and the workload balance among the ESs.Then,we reformulate the problem as an MDP problem and design DRL-based energy efficient task offloading(DEETO)algorithm to solve it.Comparative experi-ments are carried out which show the superiority of our DEETO algorithm in improving energy efficiency and balancing the workload. | Ying Chen Wei Gu Jiajie Xu Yongchao Zhang Geyong Min | 2023 | China Communications2023，20，11： | 0 |
| 8 | Antibiotic-based small molecular micelles combined with photodynamic therapy for bacterial infections显示文摘The appearance of multidrug-resistant bacteria and the formation of bacterial biofilms have necessitated the development of alternative antimicrobial therapeutics.Antibiotics conjugated with or embedded in nano-drug carriers show a great potential and advantage over free drugs,but the mass proportion of carriers generally exceeds 90%of the nano-drug,resulting in low drug loading and limited therapeutic output.Herein,we fabricated a nanocarrier using antibiotics as the building blocks,minimizing the use of carriermaterials,significantly increasing the drug loading content and treatment effect.Firstly,we conjugated betaine carboxylate with ciprofloxacin(CIP)through an ester bond to form the amphiphilic conjugate(CIP-CB),which self-assembled into micelles(CIP-CBMs)in aqueous solutions,with a CIP loading content as high as 65.4%and pH-induced surface charge reversal properties.Secondly,a model photosensitizer(5,10,15,20-tetraphenylporphyrin(TPP))was encapsulated in CIP-CBMs,generating infection-targeted photodynamic/antibiotic combined nanomedicines(denoted as TPP@CIP-CBMs).Upon accumulation at infection sites or in deep bacterial biofilms,the ester bond between the betaine carboxylate and CIP is cleaved to release free TPP and CIP,leading to a synergetic antibacterial and antibiofilm activity in vitro and in vivo. | Lijiao Yang Shaomin Song Meihui Yin Min Yang Daoping Yan Xiaohui Wan Jipeng Xiao Yuchen Jiang Yongchao Yao Jianbin Luo | 2023 | Asian Journal of Pharmaceutical Sciences2023，18，3： | 0 |
| 9 | Ultra-high Temperature Ceramic Coatings:A Review on Preparation Technology and Development Prospect显示文摘Ultra-high temperature ceramic coatings have ultra-high melting points,excellent mechanical properties and high temperature ablation resistance.These unique performance combinations turn it into a promising material for use in extreme environment structures in rockets and hypersonic vehicles,particularly nozzles,leading edges and engine components.In this paper,various preparation methods of ultra-high temperature ceramic coatings were reviewed,including plasma spraying,chemical vapor deposition,pack cementation,slurry sintering,hot pressing and their research progress.Meanwhile,some new preparation methods of high temperature coatings,such as ion beam deposition,ultrasonic spraying,metal organic frame work coating,and magnetron sputtering,were introduced.The development trend of ultra-high temperature coatings was prospected as well. | LIU Shijie WANG Li DONG Binbin XU Biao GUO Yusen MIN Yongchao GUO Yanyan WEI Haoyu ZHANG Keke YIN Chaofan | 2023 | China's Refractories2023，32，3： | 0 |
| 10 | Genome-Wide Association Study for Milled Grain Appearance Traits Using Multi-Parent Advanced Generation Intercross Population in Rice显示文摘The identification of loci and markers associated with milled grain appearance traits is essential for breeding high-yielding and good-quality rice variety.To detect stable loci for these characteristics,grain length(GL),grain width(GW),grain length/width(GLW),chalkiness degree(CD),chalky-grain rate(CR)and translucency degree(TD)of 378 rice lines were evaluated in three seasons.These lines were derived from a multi-parent advanced generation intercross(MAGIC)population. | LI Xiaoxiang LIU Jindong GUO Liang WEI Xiucai WANG Yamei PAN Xiaowu DONG Zheng LIU Wenqiang LIU Licheng MIN Jun LIU Sanxiong YE Guoyou LI Yongchao | 2023 | Rice science2023，30，5： | 0 |
| 11 | Integrated Transcriptome and Small RNA Sequencing Analyses Reveals Insights into the Molecular Mechanism of Seed Germination in Mung Bean显示文摘During the life cycle of a plant,seed germination is crucial.Upon ingestion of water,the dry seeds resumed energy metabolism and cellular repair.To dissect the complex mechanisms at the very beginning of seed germination,two approaches including transcriptome and small RNA sequencing were conducted during the water imbibition process of mung bean seeds compared with dry seed.The transcriptome sequencing analysis identified 10,108 differentially expressed genes(DEGs)between dry and imbibed mung bean seeds.KEGG enrichment analyses demonstrated numerous DEGs involved in hormone signaling pathways,carbohydrate,and energy metabolism.Out of the total DEGs,129 genes were investigated to involve in abscisic acid,gibberellin,and ethylene pathways,with 56 genes involved in glycolysis and TCA cycle.Through the analysis of small RNA sequencing among different samples,there were 284 miRNAs found in the imbibed and dried seeds of mung bean containing 213 known and 71 novel miRNAs.From comparison between the two types of seeds,51 miRNAs were differentially expressed.The integrated analyses of transcriptome and miRNAome data showed that 23 DEGs are the putative target genes of 8 miRNAs including miR156,miR171b-3p,miR166e-3p,miR169-1,etc.QRT-PCR was used to validate several DEGs and miRNAs.The data suggested that the seed imbibition process is regulated by a variety of DEGs and microRNAs.Meanwhile,we hope to gain a deeper insight into how mung bean seeds germinate in order to optimize seed growth. | Yanyan Pu Liwen Wang Leilei Li Yujun Si Shubin Xie Yunzhe Cong Dong Wang Yongchao Gong Rumei Tian Xue Chen Xiaoyan Zhang Min Liu Hanfeng Ding Nana Li | 2023 | Phyton-International Journal of Experimental Botany2023，92，6： | 0 |
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