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| 1 | Influence of H pylori on plasma ghrelin in patients without atrophic gastritis显示文摘AIM:To determine the association between H pylori infection and serum ghrelin levels in patients without atrophic gastritis.METHODS:Fifty consecutive patients(24 males and 26 females)with either H pylori-positive gastritis(n = 34)or H pylori-negative gastritis(n = 16)with normal gastric acid secretion determined by 24-h pHmetry and without atrophic gastritis in histopathology were enrolled in this study.Thirty-four H pylori-infected patients were treated with triple therapy consisting of a daily regimen of 30 mg lansoprazole bid,1 g amoxicillin bid and 500 mg clarithromycin bid for 14 d,followed by an additional 4 wk of 30 mg lansoprazol treatment.H pylori infection was eradicated in 23 of 34(67.6%)patients.H pylori-positive patients were given eradication therapy.Gastric acidity was determined via intragastric pH catethers.Serum ghrelin was measured by radioimmunoassay(RIA).RESULTS:There was no signifficant difference in plasma ghrelin levels between H pylori-positive and H pylori-negative groups(81.10 ± 162.66 ng/L vs 76.51 ± 122.94 ng/L).In addition,there was no significant difference in plasma ghrelin levels and gastric acidity levels measured before and 3 mo after the eradication therapy.CONCLUSION:H pylori infection does not influence ghrelin secretion in patients with chronic gastritis without atrophic gastritis. | Mehmet Cindoruk Ilhan Yetkin Serpil Muge Deger Tarkan Karakan Erdal Kan Selahattin Unal | 2007 | World Journal of Gastroenterology2007，13，10： | 13 |
| 2 | Effectiveness of Inactivated COVID-19 Vaccines Against Symptomatic,Pneumonia,and Severe Disease Caused by the Delta Variant:Real World Study and Evidence—China,2021显示文摘Summary What is already known about this topic?Effectiveness of China’s 2 inactivated vaccines(BBIBPCorV and CoronaVac)against pre-Delta severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)variants ranged from 47%to over 90%,depending on the clinical endpoint,and with greater effectiveness against more severe coronavirus disease 2019(COVID-19).During an outbreak in Guangdong,inactivated vaccine effectiveness(VE)against the Delta variant was 70%for symptomatic infection and 100%for severe COVID-19.However,separate or combined VE estimates for the two inactivated vaccines against Delta are not available.What is added by this report?In an outbreak that started in a hospital,VEs of completed primary vaccination with inactivated COVID-19 vaccines against symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant were 51%,61%,and 82%.Completed primary vaccination reduced the risk of progressing from mild to moderate or severe COVID-19 by 74%.VE estimates for BBIBP-CorV and CoronaVac or combined vaccination were similar,and partial vaccination was ineffective.What are the implications for public health practice?Completed primary vaccination with either of the 2 inactivated COVID-19 vaccines reduces risk of symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant.Completion of the completed primary vaccination with two doses is necessary for protection from Delta. | Dan Wu Yanyang Zhang Lin Tang Fuzhen Wang Ying Ye Chao Ma Hui Zheng Wenzhou Yu Lei Cao Yifan Song Abuduwaili Reyimu Xiaoxiao Zhang Haifeng Wang Yifei Nie Mingxia Lu Muge Qi Jun Li Ruolin Wang Kaichao Yang Changshuang Wang Lawrence Everett Rodewald Geroge Fu Gao Zhijie An Zundong Yin | 2022 | China CDC weekly2022，4，4： | 7 |
| 3 | Optimization of constitutive parameters of foundation soils k-means clustering analysis显示文摘The goal of this study was to optimize the constitutive parameters of foundation soils using a k-means algorithm with clustering analysis. A database was collected from unconfined compression tests, Proctor tests and grain distribution tests of soils taken from three different types of foundation pits: raft foundations, partial raft foundations and strip foundations.k-means algorithm with clustering analysis was applied to determine the most appropriate foundation type given the unconfined compression strengths and other parameters of the different soils. | Muge Elif Orakoglu Cevdet Emin Ekinci | 2013 | Research in Cold and Arid Regions2013，5，5： | 7 |
| 4 | Choroidal thickness measurements with optical coherence tomography in branch retinal vein occlusion显示文摘AIM: To evaluate central macular thickness(CMT) and mean choroidal thickness(MCT) in eyes with branch retinal vein occlusion(BRVO), before and after ranibizumab treatment using spectral domain-optical coherence tomography(SD-OCT).·METHODS: Forty-two patients with unilateral BRVO and macular edema were included in this study. There were 25 men and 17 women. Using SD-OCT, choroidal thickness was measured at 500 μm intervals up to 1500μm temporal and nasal to the fovea. MCT was calculated based on the average of the 7 locations. All the eyes with BRVO were treated with intravitreal ranibizumab(0.5 mg/0.05 m L). Comparisons between the BRVO and fellow eyes were analyzed using Mann-Whitney U test. Preinjection and post-injection measurements were analyzed using Wilcoxon test and repeated measure analysis.· RESULTS: At baseline, there was a significant difference between the BRVO and fellow eyes in MCT[BRVO eyes 245(165-330) μm, fellow eyes 229(157-327) μm]and CMT [BRVO eyes 463(266-899) μm, fellow eyes 235(148-378) μm(P =0.041, 0.0001, respectively)]. Following treatment, CMT [295(141-558) μm] and MCT [229(157-329) μm] decreased significantly compared to the baseline measurements(P =0.001, 0.006, respectively).Also BCVA(log MAR) improved significantly(P=0.0001) in the BRVO eyes following treatment. After treatment CMT[BRVO eyes 295(141-558) μm, fellow eyes 234(157-351) μm]and MCT [BRVO eyes 229(157-329) μm, fellow eyes 233(162-286) μm] values did not reveal any significant difference in BRVO eyes and fellow eyes(P=0.051, 0.824,respectively).· CONCLUSION: In eyes with BRVO, CMT and MCT values are greater than the fellow eyes, and decrease significantly following ranibizumab injection. | Muge Coban-Karatas Rana Altan-Yaycioglu Burak Ulas Selcuk Sizmaz Handan Canan Cagla Sariturk | 2016 | International Journal of Ophthalmology(English edition)2016，9，5： | 6 |
| 5 | 3mL和5mL利多卡因眼球筋膜囊下麻醉在超声乳化手术中的比较研究(英文)显示文摘目的:分析比较3mL和5mL利多卡因眼球筋膜囊下麻醉对白内障超声乳化手术中眼压,镇痛效果和眼外肌失运动能力的作用效果。眼球筋膜囊下麻醉是白内障超声乳化术中常用的局麻方式。作为一种剂量依赖型的阻滞方式,良好的眼压、镇痛效果以及眼外肌失运动是手术成功需要考虑的重要因素。方法:在获得伦理批准和患者的知情同意后,随机纳入70例患者作为研究对象,分别给予3m L利多卡因(组一)和5m L利多卡因(组二)作眼球筋膜囊下麻醉。麻醉前测量眼压,麻醉后10min评估眼压,镇痛效果和眼外肌失运动能力,并记录球结膜水肿和结膜下出血等并发症。结果:在麻醉管理期间,由于两名患者要求镇静,故从本研究中排除。比较组内及组间患者在麻醉前、后的基本特征,如年龄、体质量、身高、眼轴长度以及ASA生理状态,均无明显差异。与组一相比,组二患者眼外肌失运动能力及镇痛效果均明显较好。组二中有13例患者(38.2%)可达到眼球完全不运动,而组一没有患者可达到该程度。组一中有18例患者(56.3%)术中完全无痛觉,14例患者(43.7%)存在轻微痛觉,组二中有28例患者(82.4%)无痛觉,6例患者(17.6%)术中有轻微痛觉。此外,两组患者在麻醉前与麻醉后10min,其眼压的变化均无统计学差异(P<0.05)。两组患者并发症发生情况无明显差异。结论:3m L利多卡因和5m L利多卡因作眼球筋膜囊下麻醉对眼压均无影响,但在白内障超声乳化手术中给予5m L利多卡因作麻醉,在镇痛及眼外肌失运动能方面效果更好。 | Muge Coban-Karatas Oya Yalcin Cok Rana Altan-Yaycioglu | 2015 | 国际眼科杂志2015，15，11： | 6 |
| 6 | He/icobacter py/ori infection in hemodialysis patients: Susceptibility to amoxicillin and clarithromycin显示文摘AIM: To evaluate susceptibility of Helicobacter pylori to amoxicillin and clarithromycin in end-stage renal disease (ESRD) patients and non-uremic controls.METHODS: The subjects with dyspeptic complaints were 33 ESRD patients and 46 age- and sex-matched nonuremic controls who exhibited H pylori on antral biopsy specimens. The two groups were age and sex matched.The H pylori strains' pattern of susceptibility to amoxicillin and clarithromycin was investigated with the agar dilution technique.RESULTS: None of the H pylori strains from either group showed resistance to amoxicillin with the agar dilution method. Twelve (36.4%) of the ESRD group strains and 7 (15.2%) of the control group strains showed resistance to clarithromycin, and this difference was statistically significant (P<0.05).CONCLUSION: Resistance to amoxicillin does not appear to be an important problem in H pylori-infected ESRD and non-uremic patients in our region. In contrast, the rates of resistance to clarithromycin are high, particularly in the ESRD population. | Selim Aydemir Sedat Boyacioglu Gurden Gur Muge Demirbilek Fusun Kamber Can Murat Korkmaz Ugur Yilmaz | 2005 | World Journal of Gastroenterology2005，11，6： | 5 |
| 7 | Amifostine enhances the antioxidant and hepatoprotective effects of UW and HTK preservation solutions显示文摘AIM:To investigate whether amifostine contributes to the antioxidant and cytoprotective effects of histidinetryptophan-ketoglutarate(HTK)and University of Wisconsin(UW)preservation solutions.METHODS:Forty-eight Sprague Dawley male ratswere equally divided into six groups:(1)ringer Lactate(RL)group;(2)RL+amifostine(RL+A)group;(3)HTK group;(4)HTK+A group;(5)UW group;and(6)UW+A group.Rats in the RL+A,HTK+A and UW+A groups were administered amifostine intraperitoneally at a dose of 200 mg/kg prior to laparotomy.The RL group was perfused with RL into the portal vein.The RL+A group were perfused with RL into the portal vein after amifostine administration.The HTK group received an HTK perfusion while the HTK+A group received an HTK perfusion after administration of amifostine.The UW group received a perfusion of UW,while the UW+A group received a UW perfusion after amifostine administration.Liver biopsy was performed to investigate histopathological,immunochemical[transferase mediated dUTP nick end labeling(TUNEL),inducible nitric oxide syntetase(iNOS)]and ultrastructural alterations.Biochemical alterations were determined by examining levels of alanine aminotransferase,alkaline phosphatase and nitric oxide in the perfusion fluid.RESULTS:Pathological sinusoidal dilatation and centrilobular hydropic alteration were significantly lower in the groups that received amifostine prior to preservation solution perfusion.Although the best results were obtained in the UW+A group,we did not observe a statistically significant difference between the UW+A and HTK+A groups.iNOS grades were significantly lower in the amifostine groups 12 h after treatment.When the amifostine groups were compared against each other,the iNOS grades obtained from the UW+A and HTK+A groups were similar while the RL+A group had a much poorer score.TUNEL assays demonstrated a lower apoptosis ratio in the amifostine groups than in the non-amifostine groups 12 h after treatment.No statistically significant difference was observed between the UW+A and HTK+A groups for apoptosis.Cellular ultrastructure was best preserved in the UW+A and HTK+A groups.CONCLUSION:Here,we show that preoperative administration of a single dose of amifostine is sufficientto minimize the preservation damage in hepatic cells. | Sami Akbulut Sinasi Sevmis Hamdi Karakayali Nilüfer Bayraktar Muge Unlukaplan Ergun Oksuz Atilla Dagdeviren | 2014 | World Journal of Gastroenterology2014，20，34： | 3 |
| 8 | Effect of diluted povidone iodine in adenoviral keratoconjunctivitis on the rate of subepithelial corneal infiltrates显示文摘AIM: To evaluate the clinical characteristics of adenoviral keratoconjunctivitis, the management modalities, as well as the incidence of subepithelial corneal infiltrates(SEI).METHODS: Patients with characteristic clinical symptoms and signs, who presented to our clinic within the first week of symptoms and received the diagnosis of adenoviral keratoconjunctivitis between January 2013 and April 2016, were included in the study. A total of 211 patients were included in the study. Patients were evaluated for the incidence of clinical signs, late complications, management preferences, and the effect of diluted povidone-iodine(d-PVP-I) 2%. RESULTS: Patients’ mean age was 33.03±14.76 y. We observed an increase in the number of cases according to the years. At presentation and/or early follow-up, the clinical signs were conjunctival hyperemia(100%), conjunctival follicules(79.1%), edema of the eyelids(39.3%), chemosis(16.1%), pseudomembrane formation(16.6%), and corneal epitheliopathy(29.9%). During late follow-up 13.3% patients developed conjunctival subepithelial fibrosis, and 39.8% developed SEI. A significant decrease in the incidence of SEI development was observed in patients who used d-PVP-I 2%(P=0.032;33.3% vs 45.9%, respectively in patients who received d-PVP-I 2% and who did not).CONCLUSION: Adenoviral keratoconjunctivitis has a tremendous effect on patient’s comfort and abilities in short-term. Additionally, almost half of the patients develop visual problems related to SEI. According to our clinical experience, using d-PVP-I 2% in the first days of adenoviral keratoconjunctivitis might be helpful in reducing the risk of SEI as a complication. | Rana Altan-Yaycioglu Nedime Sahinoglu-Keskek Handan Canan Muge Coban-Karatas Burak Ulas | 2019 | International Journal of Ophthalmology(English edition)2019，12，9： | 2 |
| 9 | Evaluation of 532-nm KTP laser treatment efficacy on acne vulgaris with once and twice weekly applications显示文摘 | Ozlem Yilmaz Nilgun Senturk Esra Pancar Yuksel Fatma Aydin Muge Guler Ozden Tayyar Canturk Ahmetyasar Turanli | 2011 | Journal of Cosmetic and Laser Therapy2011，，6： | 2 |
| 10 | p21 and p27 immunoexpression in gastric well differentiated endocrine tumors(ECL-cell carcinoids)显示文摘AIM: To investigate the expression of cyclin-dependent kinase inhibitors p21 and p27 in gastric well differenti- ated endocrine tumors (GWDET) (ECL-cell carcinoids). METHODS: The expressions of p21 and p27 were ex- amined immunhistochemically in endoscopic biopsy specimens from 16 patients matching the diagnostic criteria of GWDET. Percentage of positive nuclear stain- ing either weak or strong was noted. The association of immunoexpressions with age, gender, tumor localization, multifocality and accompanying chronic atrophic gastritis, neuroendocrine cell hyperplasia (NEH), neuroendocrine dysplasia (NED), intestinal metaplasia (IM), Ki-67 prolif- eration index and clinical outcome were also evaluated. RESULTS: All cases expressed p27 with a mean expres- sion score of 43.6%, while 31.3% of the cases showed any p21 expression. p21 and p27 immunoexpressions were significantly correlated with each other (P < 0.01), and the p21-expressing group had higher p27 expres- sion scores (68% vs 22%). p21 and p27 expressions were lower in women, in non-atrophic mucosa and cases whose tumors were located somewhere other than fun- dus without submucosal extension. On contrary, p21 and p27 expressions were higher in males and the patients with submucosal extension and atrophic gastritis. Cases presenting lower p27 scores had solitary tumors showing neither NEH-NED nor IM. Despite, cases with lower p21 expression presented multifocal tumors accompanied by NEH-NED. However, no correlation of p21 and p27 expres- sions was found with age and Ki-67 expression. CONCLUSION: p27 is widely expressed in GWDETs, while p21 expression is sparse and observed in two thirds of the cases. Loss of p21 and p27 expressions may be cor- related with different carcinoid tumor subtypes; however,m ore studies are needed to assess the role of these pro- spective markers in gastrointestinal endocrine tumors. | Basak Doganavsargil Banu Sarsik Fatma Secil Kirdok Ahmet Musoglu Muge Tuncyurek | 2006 | World Journal of Gastroenterology2006，12，39： | 2 |
| 11 | 经角巩膜隧道不作放射状切开的青光眼小梁切除术(英文)显示文摘目的:讨论经角膜巩膜隧道所行的穿透性小梁切除术治疗青光眼。方法:最近有学者报道了五种不同类型的经角膜巩膜隧道小梁切除术,术中不需行放射状巩膜切开。其中三种术式通过与标准Cairns小梁切除术进行比较作对照研究。结果:与标准Cairns小梁切除术相比,经角巩膜隧道所行的小梁切除术术后并发症发生率明显降低,而手术成功率则不低于标准凯恩斯小梁切除术。结论:非放射状巩膜切开经角巩膜隧道小梁切除术较标准Cairns小梁切除术安全性好,而手术成功率相当。 | Avinoam Ophir Muge Karatas | 2004 | 国际眼科杂志2004，4，1： | 2 |
| 12 | Interpolation ap- proach for 3D smooth reconstruction of subsurface objects显示文摘 | SIRAKOV N M GRANADO I MUGE F H | 2002 | Computers & Geosciences2002，28，8： | 1 |
| 13 | Arch width changes in extraction and nonextraction treatment in Class I patients显示文摘 | Muge A Llken K | 2005 | Angle Orthod2005，75，6： | 1 |
| 14 | Ion-imprinted beads for molecular recognition based mercury removal from human serum显示文摘 | Muge Andac Sinem Mirel Serap Senel | 2007 | International Journal of Biological Macromolecules2007，40，： | 1 |
| 15 | Self organized data and image retrieval as a consequence of inter-dynamic synergistic relationships in artificial ant colonies 显示文摘 | Ramos V Muge F Pina P | 2002 | Frontiers in Artificial Intelligence and Applications2002，87，： | 1 |
| 16 | Arch width changes in extraction and nonextraction treatment in Class I patients显示文摘 | Muge A Liken K | 2005 | Angle Orthod2005，75，6： | 1 |
| 17 | Investigation of the possibility of using ischemia-modified albumin as a novel and early prognostic marker in cardiac arrest patients after cardiopulmonary resuscitation显示文摘 | Suleyman Turedi Abdulkadir Gunduz Ahmet Mentese Bengu Dasdibi Suleyman Caner Karahan Aynur Sahin Gamze Tuten Muge Kopuz Ahmet Alver | 2009 | Resuscitation2009，，9： | 1 |
| 18 | Is obesity a risk factor for psychopathology among adolescents? 显示文摘 | Serpil E Nurcan C Muge T | 2004 | Pediatr Int2004，46，： | 1 |
| 19 | The trend of small cell lung cancer among young men显示文摘 | OMUR C E MUGE A E | 2007 | Lung Cancer2007，57，1： | 1 |
| 20 | Interpolation approach for 3D smooth reconstruction of subsurface objects显示文摘 | Sirakova N M Granado I Muge F H | 2002 | Computers & Geo sciences2002，28，8： | 1 |
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