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| 1 | Effectiveness of Inactivated COVID-19 Vaccines Against Symptomatic,Pneumonia,and Severe Disease Caused by the Delta Variant:Real World Study and Evidence—China,2021显示文摘Summary What is already known about this topic?Effectiveness of China’s 2 inactivated vaccines(BBIBPCorV and CoronaVac)against pre-Delta severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)variants ranged from 47%to over 90%,depending on the clinical endpoint,and with greater effectiveness against more severe coronavirus disease 2019(COVID-19).During an outbreak in Guangdong,inactivated vaccine effectiveness(VE)against the Delta variant was 70%for symptomatic infection and 100%for severe COVID-19.However,separate or combined VE estimates for the two inactivated vaccines against Delta are not available.What is added by this report?In an outbreak that started in a hospital,VEs of completed primary vaccination with inactivated COVID-19 vaccines against symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant were 51%,61%,and 82%.Completed primary vaccination reduced the risk of progressing from mild to moderate or severe COVID-19 by 74%.VE estimates for BBIBP-CorV and CoronaVac or combined vaccination were similar,and partial vaccination was ineffective.What are the implications for public health practice?Completed primary vaccination with either of the 2 inactivated COVID-19 vaccines reduces risk of symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant.Completion of the completed primary vaccination with two doses is necessary for protection from Delta. | Dan Wu Yanyang Zhang Lin Tang Fuzhen Wang Ying Ye Chao Ma Hui Zheng Wenzhou Yu Lei Cao Yifan Song Abuduwaili Reyimu Xiaoxiao Zhang Haifeng Wang Yifei Nie Mingxia Lu Muge Qi Jun Li Ruolin Wang Kaichao Yang Changshuang Wang Lawrence Everett Rodewald Geroge Fu Gao Zhijie An Zundong Yin | 2022 | China CDC weekly2022，4，4： | 7 |
| 2 | Effectiveness of Catch-Up Vaccinations after COVID-19 Containment--China,2020显示文摘Introduction:In the early stages of the coronavirus disease 2019(COVID-19)epidemic in China,the highest level of public health emergency response(Level 1 Response)was launched in all province-level administrative divisions(PLADs)across the country.Provision of vaccination services was selectively suspended due to the physical distancing and gathering restrictions required of Level 1 Response.The purpose of this paper is to evaluate the impact of COVID-19 on vaccination services and the effectiveness of selective vaccination service suspension and catch-up vaccinations in China.Methods:Vaccine doses administered,routine vaccination coverage levels,catch-up vaccine doses administered,and coverage levels after the catch-up campaign were determined from individual vaccination records in sampled clinics,standard routine immunization administrative coverage reports,and catch-up vaccination activity reports submitted by PLADs between October 2019 and October 2020.Results:National Immunization Program(NIP)and non-NIP vaccine doses administered in sampled clinics decreased by 80% and 90%,respectively,compared with doses administered before the COVID-19 pandemic.Coverage with the birth dose of hepatitis B vaccine(HepB1)and the Bacillus Calmette-Guérin vaccine(BCG)—two vaccinations recommended to continue throughout the epidemic due to their timecritical nature—were maintained at over 85%,while coverage of other NIP vaccines decreased to below 60%by February 2020.Catch-up vaccination coverage of the 29 PLADs,excluding Xinjiang and Xizang(Tibet),began in April 2020 and exceeded 90%;Hubei catch-up coverage was 95% by October 2020.Conclusions and Implications for Public Health Practice:The COVID-19 pandemic had a great impact on China’s vaccination services.During the epidemic and time of local transmission of the coronavirus,HepB1,BCG,rabies vaccine for postexposure prophylaxis,and tetanus antitoxin(TAT)for wound prophylaxis were maintained at high levels.Of the 69 million vaccine doses postponed during the time of local transmission of the coronavirus,94% were administered in the catch-up campaign.China’s pandemic immunization practices may provide evidence for other countries’immunization programs. | Jing Wu Wenzhou Yu Lei Cao Lingsheng Cao Lance Rodewald Jiakai Ye Yifan Song Li Li Xiaoxue Liu Ning Wen Fuzhen Wang Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Yanmin Liu Guomin Zhang Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，50： | 6 |
| 3 | Gene expression profiling in porcine mammary gland during lactation and identification of breed- and developmental-stage-specific genes显示文摘A total of 28941 ESTs were sequenced from five 5?-directed non-normalized cDNA li-braries, which were assembled into 2212 contigs and 5642 singlets using CAP3. These sequences were annotated and clustered into 6857 unique genes, 2072 of which having no functional annotations were considered as novel genes. These genes were further classified into Gene Ontology categories. By comparing the expression profiles, we identified some breed- and developmental-stage-specific gene groups. These genes may be relative to reproductive performance or play important roles in milk synthesis, secretion and mammary involution. The unknown EST sequences and expression profiles at different developmental stages and breeds are very important resources for further research. | SU Zhixi1, DONG Xinjiao2, ZHANG Bing1, ZENG Yanwu1, FU Yan1, YU Jun1,3 & HU Songnian1,3 1. James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310008, China 2. School of Life and Environmental Sciences, Wenzhou Normal College, Wenzhou 325027, China 3. Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101300, China | 2006 | Science China(Life Sciences)2006，49，1： | 3 |
| 4 | The Karyotypes, C-banding Patterns and AgNORs of Epinephelus malabaricus显示文摘The chromosome specimens of Epinephelus malabaricus (Bloch & Schneider, 1801) are obtained from metaphase of kindney cell by vivi-injection of PHA and culture of colchicines, hypatoic-air drying technique, and then by studying their Giemsa stain, C-bands and AgNORs. The results are as follows: (1)E. malabaricus has a diploid chromosome number of 48 and its karyotype formula is 48t, NF=48, sex chromosome is not found. (2) There is a pair of chromosomes with secondary constriction near the centromere of chromosome t24. (3) 1~4 nucleoli appear in the nucleus of interphase, 55% nuclei has 1 nucleolus and only 2% for 4 nucleoli. (4) AgNORs appear in the chromosome t24 of 50% metaphase, sometimes in the chromosome t5, but not in other chromosomes. (5) The AgNORs polymorphisms are individually specific, 1~4 pairs of the number, and the frequency of 4 AgNORs are lowest. (6) The secondary constrictions and positive C-bands are coincident, close to the centromere of the chromosome, and mass constrictive heterochromatins appear in that region. (7) All the centromeres of chromosomes are darkly stained C-bands, and the whole arm of chromosome t24 and its centromere are same positive C-bands. (8) The evolutive regulation of the karyotype and the developing mechanism of AgNORs and C-bands are discussed. | 邹记兴 Hu Chaoqun Xiang Wenzhou YU Qixing Zhou Fei | 2004 | High Technology Letters2004，10，2： | 2 |
| 5 | CALCULATIONS TO ITS FATIGUE DAMAGE FRACTURE AND TOTAL LIFE UNDER MANY-STAGE LOADING FOR A CRANK SHAFT显示文摘CALCULATIONSTOITSFATIGUEDAMAGEFRACTUREANDTOTALLIFEUNDERMANY-STAGELOADINGFORACRANKSHAFTCALCULATIONSTOITSFATIGUEDAMAGEFRACTUREA... | Yu Yangui Zhang Wenbin (Wenzhou University) | 1994 | Chinese Journal of Mechanical Engineering1994，7，4： | 2 |
| 6 | Coverage of 13-Valent Pneumococcal Conjugate Vaccine Among Children 0–15 Months of Age—9 Provinces,China,2019–2021显示文摘Summary What is already known on this topic?Limited data exist regarding the coverage of the 13-valent pneumococcal conjugate vaccine(PCV13)in China.A lack of official statistics,coupled with an insufficient body of published literature,hinders the accurate depiction of the current situation.What is added by this report?This study investigated the utilization of PCV13 and estimated its coverage in nine provinces across eastern,central,and western China between 2019 and 2021.Despite an annual increase in PCV13 usage during this period,the overall coverage remained suboptimal. | Lijun Liu Zhaonan Zhang Xixi Zhang Changsha Xu Yifan Song Li Li Jiakai Ye Zhiguo Wang Hui Liang Weiyan Zhang Ling Lin Ning Li Shujun Zhang Qianli Ma Wen Du Yongzhuo Jiao Lingsheng Cao Qi Qi Lei Cao Wenzhou Yu | 2023 | China CDC weekly2023，5，17： | 1 |
| 7 | The Research of Bubble Adsorption to Purify Silicon in the A1-Si System显示文摘 | Yu Wenzhou Ma Wenhui | 2013 | Materials Science Forum2013，750，： | 1 |
| 8 | Prevalence of hypertension in a hemodialysis population显示文摘Objective To know the accurate information on prevalence and status of blood pressure (BP) control in hemodialysis patients. Methods The pre/post mid week dialysis BP readings of 114 patients (74 males, 40 females. the average age 49.2±11.6 years) were evaluated. Hypertension was defined as BP>150/90mm Hg. Hypertension was further characterized according to whether the patients had normal or elevated pre dialysis systolic, pre dialysis diastolic, post dialysis systolic or post dialysis diastolic BP reading on 6 sequential dialysis recordings. And the systolic and diastolic pressure was separately graded from 0 to3 and a number designed as hypertension sensitivity index (HSI) was assigned to each patient. Results Of the 114 patients,97(85.1%)were hypertenisve,87(76.3%) had persistent elevation of BP despite being on one or more antihypertensive medication.The mean HSI for this population was 3.7±2.2.Most patients(81.9%) were on calcium channel blockers,29.1% being on Angiotension converting enzyme inhibitors(ACEI) and 29.2% on α blockers.There was correlation between pre dialysis systolic,pre dialysis diastolic BP and the post dialysis body weight change rate with dry weight.Conclusion Hypertension was a frequent finding in our hemodialysis population.Most of this hypertension was pre dialysis systolic.There was significant correlation between pre dialysis BP and post dialysis body weight change rate with dry weight. | LIU Yi,XU Yu lan,ZHEN Chen fei,WANG Lu ping | 2000 | Chinese Journal of Biomedical Engineering(English Edition)2000，9，3： | 1 |
| 9 | Preparation and Spectral Characterization of 3-Benzyl-6-aryl-1,2,4-triazolothiadiazoles显示文摘Benzyl 4 amino 5 mercapto 1,2,4 triazole reacted with aromatic acids in the presence of phosphorus oxychloride, yielding a series of new compounds, i.e. , 3 benzyl 6 aryl 1,2,4 triazolothiadiazoles, each of which has an active methylene at 3 position. The structures of all the title compounds were confirmed by elementary analysis, IR, 1H NMR and 13 C NMR spectra. | ZHANG Li xue 1** , ZHANG An jiang 1, CHEN Guang 1CHEN Fei yu 1, JIANG Yi ping 1 and ZHANG Zi yi 21. Department of Chemistry, Wenzhou Teachers College, Wenzhou 325003, P. R. China 2. Department of Chemistry, Lanzhou University, Lanzhou 730 | 2002 | Chemical Research in Chinese Universities2002，18，3： | 1 |
| 10 | Association Between IL-4 Polymorphisms and Risk of Liver Disease: An Updated Meta-Analysis显示文摘 | Zhitong Wu Wenzhou Qin Jie Zeng Chunni Huang Yu Lu Shan Li | 2015 | Medicine2015，，35： | 1 |
| 11 | Vaccination Guidelines During and After the COVID-19 Epidemic in China显示文摘In late December 2019,clinicians in Hubei Province noticed and reported to health authorities a cluster of cases of pneumonia of unknown etiology(PUE)that turned out to be the start of the coronavirus disease 2019(COVID-19)pandemic(1).By January 29,2020,all provincial-level administrative divisions(PLADs)across the country had launched their highest public health emergency responses(Level 1 responses)(2-3). | Wenzhou Yu Yuanqiu Li Jing Wu Fuzhen Wang Ning Wen Lance Rodewald Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Lei Cao Lingsheng Cao Jiakai Ye Yanmin Liu Guomin Zhang Wen Du Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，34： | 1 |
| 12 | Vaccination Vehicles for COVID-19 Immunization—China,2021显示文摘Background:Recently,developed vaccination vehicles were repurposed and deployed for coronavirus disease 2019(COVID-19)vaccination in China.We described the vehicles and reported an evaluation of vaccination throughput of these vehicles for COVID-19 vaccination in China.Methods:We obtained daily reports of COVID-19 vaccine doses administered in vehicles in Hubei Province between March 16 and 29 of 2021.We determined the rate of COVID-19 vaccines given and evaluated the applicability of vaccination vehicles for COVID-19 vaccination.Results:Vehicles with 2 vaccination stations are suitable for several real-world scenarios.Vehicles administered an average of 72 COVID-19 vaccine doses per hour,with an upper limit of 145 doses per hour.Conclusion:Vaccination vehicles can save human and financial resources and provide high quality,effective,convenient,and rapid on-site vaccination services;they can increase the pace of COVID-19 vaccination. | Hong Lei Lingsheng Cao Yi Gong Wenzhou Yu Lei Cao Jiakai Ye Yifan Song Li Li | 2021 | China CDC weekly2021，3，34： | 0 |
| 13 | Vaccine-Associated Paralytic Poliomyelitis--8 PLADs,China,October 2012–March 2014显示文摘Introduction:Poliomyelitis is a highly contagious,seasonal viral disease caused by any of three poliovirus(PV)serotypes(types 1,2,or 3).Oral poliovirus vaccine(OPV)on rare occasions causes vaccineassociated paralytic poliomyelitis(VAPP)in recipients of OPV and close contacts of recently vaccinated individuals.This study describes the epidemiology of VAPP when an all OPV schedule was used in the Expanded Program on Immunization(EPI).Methods:VAPP cases were identified using standardized diagnostic criteria from data reported by 8 provincial-level administrative divisions(PLADs)to the National Acute Flaccid Paralysis(AFP)Surveillance System in an 18-month period between October 2012 and March 2014.Results:During this period,28 VAPP cases were reported.Using the number of births as a denominator,the estimated incidence of VAPP was 2.47 cases per million births.Using the number of OPV doses administered through routine immunization,the VAPP incidence was 0.55 cases per million doses.Among vaccine-recipient VAPP cases,22(85%)were associated with the first dose of OPV;3 were associated with the second OPV dose.The relative risk of VAPP following the first dose compared with the second dose was 7.07.Conclusions and Implications for Public Health Practice:The per-dose and per-child incidences of VAPP were consistent with incidence estimates by the World Health Organization(WHO).The vast majority(85%)of VAPP in China was associated with the first dose of OPV in an all-OPV schedule.Because inactivated polio vaccine(IPV)is known to prevent VAPP from subsequent doses of OPV in immunocompetent children,this association provided strong evidence for using an IPV-first,sequential IPVOPV polio vaccination schedule in China during the globally-synchronized cessation of type 2 OPV and introduction of IPV in 2016. | Ning Wen Fang Fang Wenbo Xu Huaqing Wang Yong Zhang Qiru Su Yao Liu Haibo Wang Shuangli Zhu Xiaoxiao Zhang Wenzhou Yu Dongmei Yan Zhenguo Zhang Qiu Tan Fubao Ma Aihu Dong Yu Liu Keli Li Li Zheng Lixin Hao Dongyan Wang Chunxiang Fan Wendi Wu Huiming Luo Aiqiang Xu Weizhong Yang | 2020 | China CDC weekly2020，2，50： | 0 |
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