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| 1 | Fully covered metal biliary stents: A review of the literature显示文摘Fully covered self-expandable metal stents(FCSEMS)represent the latest advancement of metal biliary stents used to endoscopically treat a variety of obstructive biliary pathology.A large stent diameter and synthetic covering over the tubular mesh prolong stent patency and reduce risk for tissue hyperplasia and tumor ingrowth.Additionally,FCSEMS can be easily removed.All these features address issues faced by plastic and uncovered metal stents.The purpose of this paper is to comprehensively review the application of FCSEMS in benign and malignant biliary strictures,biliary leak,and post-sphincterotomy bleeding. | Robert Lam Thiruvengadam Muniraj | 2021 | World Journal of Gastroenterology2021，27，38： | 4 |
| 2 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 3 | New cloud vaporzone (CVZ) coupled headspace solid-phase microextraction technique 显示文摘 | HUANG Y C SU Y S MUNIRAJ S | 2007 | Analytical and Bioanalytical Chemistry2007，388，2： | 1 |
| 4 | Acute pancreatitis显示文摘 | Muniraj T Gajendran M Yhiruvengadam S | 2012 | Dis Mon2012，58，3： | 1 |
| 5 | Gut Colonization of mice with actA-negative mutant of Listeria monocytogenes can Stimulate a humoral mucosal immune response显示文摘 | MUNIRAJ MANOHAR DONALD O BAUMANN | 2001 | Infect Immunt2001，69，6： | 1 |
| 6 | Pancreatic neuroendocri- netumors显示文摘 | Muniraj T Vignesh S Sherry S | 2013 | Dis Mon2013，59，1： | 1 |
| 7 | Pancreatic neurovndocrine tumors显示文摘 | Muniraj T Vignesh S Shetty S | 2013 | Dis Men2013，59，1： | 1 |
| 8 | Antiobesity and antihyperlipidemic effect of Ixora coccinea on Triton X-100 induced hyperlipidemia in rats: An approach to evaluate asymmetrical temperature distribution analysis using thermography显示文摘Objective: Obesity and hyperlipidemia is the major cause of many pathological diseases with an increase side effects using allopathic drugs. The present study focuses on the effect of Ixora coccinea on Triton X-100 induced hyperlipidemia in rats and associated complications.Methodology: In vitro radical scavenging activity of I. coccinea was assessed using DPPH, FRAP and hydrogen peroxide. In vivo antiobesity and antihyperlipidimic activity of I. coccinea was tested in Triton X-100 induced hyperlipidemic rats and assessed for its biochemical parameters in blood and tissue samples.The relationship between physiological responses and regulation of body temperature was investigated by using animal surface temperature images captured with infrared camera.Results: The results of mineral analysis, antioxidant, total flavonoid and phenolic content represented high amount of mineral and had the potential to scavenge free radicals tested with DPPH, FRAP and hydrogen peroxide radicals with dose dependent activity. The highest activity was observed in aqueous extract, DPPH with 71.5% inhibition, FRAP with 56.8%, H2 O2 with 33% activity at 100 μg/mL concentration.Triton X-100 induced hyperlipidemic rats when treated with I. coccinea aqueous extract showed significant activity by regulating the biochemical parameters and maintaining the lipid profile by decreasing TC,LDL-C, VLDL-C, TG and improving HDL-C levels. Similarly, the elevated levels of creatinine, urea, uric acid,AST, ALT, ALP due to induction of hyperlipidemia, were brought back to near normal levels after treatment with I. coccinea. The levels of tissue anti-oxidants enzymes like SOD and CAT were also found to be improved in treated I. coccinea groups. The whole body asymmetrical temperature distribution analysis showed that significant decreases in temperature was observed in obesity induced groups but a gradual increase in temperature(2%–5%) was observed after treatment.Conclusion: Thus, the results indicated that I. coccinea can be a drug of choice to decrease the risk of complications associated with hyperlipidemia and obesity. | Sidhra Syed Zameer Ahmed Syed Zameer Ahmed Khader Krishnaveni Radhakrishnan Vanmathi Marimuthu Muniraj Chinnusamy Venkatesan Thangavel Karamchand Ravi Manimaran Vetrivel | 2019 | Chinese Herbal Medicines2019，11，3： | 1 |
| 9 | New cloud vapor zone (CVZ) coupled headspace solid-phase microextraction technique显示文摘 | Huang Y C Su Y S Muniraj S | 2007 | Analytical and Bioanalytical Chemistry2007，388，2： | 1 |
| 10 | Alternative uses of lumen apposing metal stents显示文摘The advent of lumen apposing metal stents(LAMS)has revolutionized the management of many complex gastroenterological conditions that previously required surgical or radiological interventions.These procedures have garnered popularity due to their minimally invasive nature,higher technical and clinical success rate and lower rate of adverse events.By virtue of their unique design,LAMS provide more efficient drainage,serve as conduit for endoscopic access,are associated with lower rates of leakage and are easy to be removed.Initially used for drainage of pancreatic fluid collections,the use of LAMS has been extended to gallbladder and biliary drainage,treatment of luminal strictures,creation of gastrointestinal fistulae,pancreaticobiliary drainage,improved access for surgically altered anatomy,and drainage of intra-abdominal and pelvic abscesses as well as post-surgical fluid collections.As new indications of endosonographic techniques and LAMS continue to evolve,this review summarizes the current role of LAMS in the management of these various complex conditions and also highlights clinical pearls to guide successful placement of LAMS. | Prabin Sharma Thomas R McCarty Ankit Chhoda Antonio Costantino Caroline Loeser Thiruvengadam Muniraj Marvin Ryou Christopher C Thompson | 2020 | World Journal of Gastroenterology2020，26，21： | 1 |
| 11 | Diabetes and pancreatic cancer 显示文摘 | Muniraj T Chari ST | 2012 | Minerva Gastroenterol Dietol2012，58，4： | 1 |
| 12 | Chronic pancreatitis, a comprehensive review and update. Part I: Epidemiology, etiology, risk factors, genetics, pathophysiology, and clinical features显示文摘 | Thiruvengadam Muniraj Harry R. Aslanian James Farrell Priya A. Jamidar | 2014 | Disease-a-Month2014，，12： | 1 |
| 13 | Pancreatic neuroendocrine tumors显示文摘 | Muniraj T Vignesh S Shetty S | 2013 | Dis Mon2013，59，1： | 1 |
| 14 | Image registration in digitalimages for variability in VEP显示文摘 | Sivanandan N Muniraj NR | 2011 | IJCSI2011，8，3： | 1 |
| 15 | Encryption and volumetric 3D object reconstruction using multispectral computational in- tegral imaging 显示文摘 | Muniraj I Kim B Lee B G | 2014 | Apply Optics2014，53，27： | 1 |
| 16 | Acute Pancreatitis显示文摘 | Muniraj T Gajendran M Thiruvengadam S | | 0，，03： | 1 |
| 17 | Hypertriglyceridemia independent propo- fol-induced pancreatitis显示文摘 | Muniraj T Aslanian HR | 2012 | JOP2012，13，： | 1 |
| 18 | Pancreatic neuroen- docrinetumors显示文摘 | Muniraj T Vignesh S Shetty S | 2013 | Dis Mon2013，59，1： | 1 |
| 19 | Chronic pancreatitis, a comprehensive review and update. Part II: Diagnosis, complications, and management显示文摘 | Thiruvengadam Muniraj Harry R. Aslanian James Farrell Priya A. Jamidar | 2015 | Disease-a-Month2015，，： | 1 |
| 20 | 3D visualization at low light levels using multispectral photon counting integral imaging显示文摘 | MOON I MUNIRAJ I JAVIDI B | | 0，，01： | 1 |
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