|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Genome size and sequence composition of moso bamboo: A comparative study显示文摘Moso bamboo (Phyllostachys pubescens) is one of the world's most important bamboo species. It has the largest area of all planted bamboo―over two-thirds of the total bamboo forest area―and the highest economic value in China. Moso bamboo is a tetraploid (4x=48) and a special member of the grasses family. Although several genomes have been sequenced or are being sequenced in the grasses family, we know little about the genome of the bambusoids (bamboos). In this study, the moso bamboo genome size was estimated to be about 2034 Mb by flow cytometry (FCM), using maize (cv. B73) and rice (cv. Nipponbare) as internal references. The rice genome has been sequenced and the maize genome is being sequenced. We found that the size of the moso bamboo genome was similar to that of maize but significantly larger than that of rice. To determine whether the bamboo genome had a high proportion of repeat elements, similar to that of the maize genome, approximately 1000 genome survey sequences (GSS) were generated. Sequence analysis showed that the proportion of repeat elements was 23.3% for the bamboo genome, which is significantly lower than that of the maize ge-nome (65.7%). The bamboo repeat elements were mainly Gypsy/DIRS1 and Ty1/Copia LTR retrotrans-posons (14.7%), with a few DNA transposons. However, more genomic sequences are needed to con-firm the above results due to several factors, such as the limitation of our GSS data. This study is the first to investigate sequence composition of the bamboo genome. Our results are valuable for future genome research of moso and other bamboos. | GUI YiJie1, WANG Sheng1, QUAN LiYan1, ZHOU ChangPing2, LONG ShiBao2, ZHENG HuaJun3, JIN Liang1, ZHANG XianYin 1, MA NaiXun 4 & FAN LongJiang1 1 Institute of Crop Science/Institute of Bioinformatics, Zhejiang University, Hangzhou 310029, China 2 Zhejiang Anji Bamboo Exposition Garden, Anji 313300, China 3 Chinese National Human Genome Center at Shanghai, Shanghai 201203, China 4 The Research Institute of Subtropical Forestry, Chinese Academy of Forestry, Fuyang 311400, China | 2007 | Science China(Life Sciences)2007，50，5： | 10 |
| 2 | microRNAs-powerful repression comes from small RNAs显示文摘microRNAs (miRNAs) encode a novel class of small, non-coding RNAs that regulate gene expression post-trancriptionally. miRNAs comprise one of the major non-coding RNA families, whose diverse bio- logical functions and unusual capacity for gene regulation have attracted enormous interests in the RNA world. Over the past 16 years, genetic, biochemical and computational approaches have greatly shaped the growth of the field, leading to the identification of thousands of miRNA genes in nearly all metazoans. The key molecular machinery for miRNA biogenesis and silencing has been identified, yet the precise biochemical and regulatory mechanisms still remain elusive. However, recent findings have shed new light on how miRNAs are generated and how they function to repress gene expression. miRNAs provide a paradigm for endogenous small RNAs that mediate gene silencing at a genome-wide level. The gene silencing mediated by these small RNAs constitutes a major component of gene regu- lation during various developmental and physiological processes. The accumulating knowledge about their biogenesis and gene silencing mechanism will add a new dimension to our understanding about the complex gene regulatory networks. | MA Cong, LIU YuFei & HE Lin 535 LSA, Division of Cell and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, CA 94720-3200 | 2009 | Science China(Life Sciences)2009，52，4： | 7 |
| 3 | New Development of China-Russia-India Triangle显示文摘Since 2001, positive improvement has occurred in the trianglerelationship between China, Russia and India. The foreignministers of the three nations met in Russia recently, symbolizingthe launching of substantive triangular cooperation. | Ma Jiali is Research Professor at CICIR. He specializes in South Asian security, especially in India’s foreign policy. He is the author of three books, such as Pay Close Attention to India: A Rising Power which is very influential. He was one of the delegates for Track Two Dialogue between China and India for all of four rounds and a delegate for Track Two Dialogue between China, Russia and India. He is also a member of Eminent Persons Group Forum between China and India. | 2005 | Contemporary International Relations2005，15，7： | 4 |
| 4 | Abortifacient Potential of Aqueous Extract of Senna alata Leaves in Rats显示文摘Objective To study the abortifacient activity of aqueous extract of Senna alata leaves in female Wistar rats.Methods Pregnant rats weighing 143.65 ± 13.11 g were completely randomized into 5 groups(A-E).Rats in group A(negative control) were orally administered,once daily with 0.5 ml of distilled water on days 10-18 post-coitum while those in groups B,C,D,and E were treated exactly like the negative control except they received the same volume containing 2.85 mg/kg body weight of mifepristone(group B,reference drug),250,500 and 1 000 mg/kg body weight of the extract respectively(groups C-E).Results Phytochemical screening of the extract showed positive results for saponins(1.22%),flavonoids(1.06%),cardiac glycosides(0.20%),cardenolides and dienolides(0.18%),phenolics(0.44%) and alkaloids(0.52%).Respiratory distress,salivation,diarrhoea,changes in the appearance of hair as well as maternal mortality were not observed at any time during the exposure period except in the mifepristone-treated animals where there was episode of diarrhoea and tiredness.The extract significantly reduced(P<0.05) the number of life foetus,weight and survival ratio of the foetus,numbers of implantations and Corpora lutea,implantation index,progesterone,prolactin,estradiol,follicle stimulating and luteinizing hormones whereas the number of dead foetus,number and percentage of rats that aborted,percentage vaginal opening,resorption index,pre-and post-implantation losses increased significantly.In addition,mifepristone-treated animals produced resorption index that compared well with the distilled water control.There was also no dead or life foetus and serum progesterone concentration was increased in the animals treated with mifepristone.All cases of abortion were accompanied with vaginal bleeding.Although,the final weight of the rats increased significantly,the feed and water intake were not significantly altered in all the treatment groups.The weight of the uterus,uterine-body weight ratio,length of the right uterus horn and uterine cholesterol decreased significantly in all the treatment groups.The uterine alkaline phosphatase activity and glucose concentration increased in only the extract-treated animals whereas mifepristone decreased the uterine alkaline phosphatase activity and glucose content of the animals.Conclusion This study has provided evidence to the age-long claim of S.alata leaves in 'washing the uterus'.The abortifacient properties were most pronounced at 500 and 1 000 mg/kg body weight of the extract and were similar to the animals treated with 2.85 mg/kg body weight of mifepristone.Hormonal influence,changes in implantation site,estrogenicity and uterogenicity are suggested as possible mechanism of abortifacient activity of aqueous extract of S.alata leaves.Overall,the extract may be used as an abortifacient especially at 500 and 1 000 mg/kg body weight and therefore not safe for consumption as oral remedy during pregnancy. | Yakubu MT Adeshina AO Oladiji AT Akanji MA Oloyede OB Jimoh GA Olatinwo AWO Afolayan AJ | 2010 | Journal of Reproduction and Contraception2010，21，3： | 2 |
| 5 | Evaluation of the antiedematogenic activity of artemetin isolated from Cordia curassavica DC显示文摘 | Bayeux MC Fernandes AT Foglio MA | 2002 | Braz J Med Biol Res2002，35，10： | 1 |
| 6 | Emergence of a new antibiotic resistance m echanism in India,Pakistan,and the UK:a molecular,biological,andepidemiological study显示文摘 | Kumarasamy KK Toleman MA Walsh TR at al | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 7 | Reproducibility of dynamic contrast-enhanced MRI in human muscle and tnmours: comparison of quantitative and semi-quantitative analysis 显示文摘 | Galbraith SM Lodge MA Taylor N J et at | 2002 | NMR Biomed2002，15，： | 1 |
| 8 | American Society of Clinical Oncology 2009 clinical evidence review on radiofre- quency ablation of hepatic metastases from colorectal cancer 显示文摘 | Wong SL Mangu PB Choti MA et at | 2010 | J Clin Oncol2010，28，3： | 1 |
| 9 | The outcomes and complica- tions of 1,2-intercompartmental supraretinacular artery pedieled vas- cularized bone grafting of scaphoid nonunions 显示文摘 | Chang MA Bishop AT Moran SL | 2006 | Hand Surg Am2006，31，3： | 1 |
| 10 | Effects of electroacupuncture on ethanol- induced impairments of spatial learning and memory and Fos expres- sion in the hippocampus in rats 显示文摘 | Lu B Ma Z Cheng F et at | 2014 | Neurosci Lett2014，576，： | 1 |
| 11 | Acute effects of irradiation on cognition: Changes in attention on a computerized continuous performance test during radiotherapy in pediatric patients with localized primary brain tumors显示文摘 | Merchant TE Kiehna EN Miles MA at al | 2002 | Journal of Radiation Oncology Biology and Physiology2002，53，5： | 1 |
| 12 | Infrared absorption of nitro- gen-oxygen complex in silicon显示文摘 | Yang D Ma X Fan R et at | 2000 | Mater Sci Eng B2000，72，2： | 1 |
| 13 | Do inflammation and pro- coagulation biomarkers contribute to the metabolic syndrome cluster 显示文摘 | Kraja AT Province MA Amett D | 2007 | Nutr Metab(London)2007，4，1： | 1 |
| 14 | Dosimetric evaluation for pulsed low dose rate radiation therapy using ARC delivery techniques显示文摘 | Ma CM Lin MH Wang L et at | 2011 | Med pHys2011，38，12： | 1 |
| 15 | Geology and geochemistry of Changba SEDEX Pb-Zn deposit, Qinling orogenic belt, China显示文摘 | Ma G L Georges B Qi S J et at | 2004 | Mineralium Deposita2004，39，3： | 1 |
| 16 | Severity of Helicobacter-induced gastric injury correlates with gastric juice ammonia 显示文摘 | Triebing AT Korsten MA Plugosz JW | 1991 | Dig Dis Sci1991，36，： | 1 |
| 17 | The development, maturation, and turnover rate of mouse spleen dendritic cell populations显示文摘 | Kamath AT Pooley J OKeeffe MA | 2000 | J Immunol2000，165，12： | 1 |
| 18 | Effeets of the angiotensin II receptor blocker losartan on the monocyte expression of biglycan in hypertensive patients 显示文摘 | Sardo MA Mandraffino G Riggio S at al | 2010 | Clin Exp Pharmacol Physiol2010，37，9： | 1 |
| 19 | The ecological importance of the Staphylococcus sciuri species group as a reservoir for resistance and virulence genes显示文摘 | Nemeghaire S Argudín MA Feβler AT | 2014 | Vet M icrobiol2014，171，34： | 1 |
| 20 | Effects of Radix scutellariae and Rhizoma atractylodis on LPS-induced abortion andthe uterine IL-10 contents in mice显示文摘 | Zhong XH Shi WY Ma AT | 2008 | Am J Chin Med2008，36，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员