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15篇 您的检索式:作者名="Mahmoud MF"
    题名 作者 年代 出处 被引量
1Inhibition of TNF-αprotects against hepatic ischemia-reperfusion injury in rats via NF-κB dependent pathway显示文摘Mahmoud MF El Shazly SM Barakat W 2012Naunyn Schmiedebergs Arch Pharmacol2012,385,5:1
2Anti-inflammatory effect of atorvastatin on vascular reactivity and insulin resistance infructose fed rats显示文摘Mahmoud MF E1-Nagar M E1-Bassossy HM 2012Arch Pharm Res2012,35,1:1
3Anti-in- flammatory effect of atorvastatin on vascular reactivity and insulin resistance in fructose fed rats 显示文摘Mahmoud MF El-Nagar M El-Bassossy HM 2012Arch Pharm Res2012,35,1:1
4Negative association of the HLA DQB1 02 allele with breast cancer development a- mongJordanians显示文摘Atoum MF Tanashat RQ Mahmoud SA 2013Asian Pac J Cancer Prey2013,14,11:1
5Assessment of neutrophil apoptosis ex vivo in hepatosplenic patients with neutropenia pre and post sptenectomy显示文摘Aref SE Mahmoud LA E1 Refie MF 2003Hematology2003,8,4:1
6Quercetin protects against diabetes-induced exaggerated vasoeonstriction in rats: effect on low grade inflammation 显示文摘Mahmoud MF Hassan NA E1 Bassossy HM 2013PLoS ONE2013,8,63:1
7Effect of Cordyceps sinensis and taurine either alone or in combination on streptozotocin induced diabetes显示文摘El ZZEA Mahmoud MF El MN 2012Food Chem Toxicol2012,50,34:1
8Evaluation of the hepatoprotec- tive effect of green tea extract and selenium on CCIA - induced fi- brosis 显示文摘Mahmoud MF Fahmy A Auf MA 2012e - SPEN Journal2012,7,1:1
9Anti-inflammatoryeffect of atorvastatin on vascular reactivity and insulin resistance infructose fed rats显示文摘Mahmoud MF El-Nagar M El-Bassossy HM 2012Arch Pharm Res2012,35,1:1
10Assessment of neutrophil apoptosis ex vivo in hepatosplenic patients with neutropenia pre and post splenectomy显示文摘Aref SE Mahmoud LA El Retie MF 2003Hematology2003,8,4:1
11Pioglitazone protects against cisplatin induced nephrotoxicity in rats and potentiates its anticancer activity against human renal adenocarcinoma cell lines 显示文摘Mahmoud MF E1 Shazly SM 2013Food Chem Toxicol2013,51,:1
12Inhibition of TNF-alpha protects a- gainst hepatic ischemia-reperfusion injury in rats via NF-kappaB de- pendent pathway显示文摘Mahmoud MF E1 SS Barakat W 2012Naunyn Schmiedebergs Arch Pharmacol2012,385,5:1
13Boronated carbons:Structural characterization and low temperature physical properties of disorderedsolids显示文摘OTTAVIANI B DERREA GRIVEI E MAHMOUD OAM GUIMON MF FLANDROIS S DELHAES P 1998J Mater Chem1998,8,1:1
14Aqueous garlic extract alleviates liver fibrosis and renal dysfunction in bile - duct - ligated rats 显示文摘Mahmoud MF Zakaria S Fahmy A 2014Z Natuforsch C2014,69,:1
15Does granulocyte-colony stimulating factor administration induce damage or repair response in schistosomiasis?显示文摘AIM:To introduce Granulocyte-colony stimulating factor (G-CSF) as a new therapeutic modality for schistosomiasis through stem cell mobilization,immunomodulation or fibrosis remodeling. METHODS:In this study,a 5 d course of human recombinant G-CSF (100 μg/kg sc) was applied to Schis-tosoma mansoni-infected mice at different stages of disease (5 d before infection as well as 3,5 and 7 wk post-infection). The animals were sacrificed at 10 d as well as 4,6 and 8 wk post infection. Mice were examined for:(1) Total leukocyte count which is an accepted surrogate marker for the stem cell mobilization into the circulation; (2) Egg count in intestine and liver tissue to assess the parasitic load; and (3) Histopathological changes in Hx/E and Masson trichrome stained sections as well as collagen content in Sirius redstained liver sections to determine the severity of liver fibrosis. RESULTS:Mice developed leukocytosis. The egg load and the number of granulomas were not affected by the G-CSF treatment but there was an obvious change in the composition of granulomas towards an increased cellularity. Moreover,fibrosis was significantly decreased in treated groups compared to untreated animals (collagen content either preinfection or at 3 and 5 wk post infection:5.8 ± 0.5,4.7 ± 0.5,4.0 ± 0.7 vs 8.2 ± 0.9; P ≤ 0.01). CONCLUSION:Although G-CSF did not cause direct elimination of the parasite,it enhanced granulomatous reaction and reduced the fibrosis. Further investigation of the underlying mechanisms of these two actions is warranted.Lobna Y Ghanem Uta Dahmen Olaf Dirsch Mona MF Nosseir Soheir S Mahmoud Wafaa AF Mansour 2010World Journal of Hepatology2010,2,12:0
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