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| 1 | Adiponectin: Probe of the molecular paradigm associating diabetes and obesity显示文摘Type 2 diabetes is an emerging health challenge all over the world as a result of urbanization, high prevalence of obesity, sedentary lifestyle and other stress related factors compounded with the genetic prevalence. The health consequences and economic burden of the obesity and related diabetes mellitus epidemic are enormous. Different signaling molecules secreted by adipocytes have been implicated in the development of obesity and associated insulin resistance in type 2 diabetes. Human adiponectin, a 244-amino acid collagen-like protein is solely secreted by adipocytes andacts as a hormone with anti-inflammatory and insulinsensitizing properties. Adiponectin secretion, in contrast to secretion of other adipokines, is paradoxically decreased in obesity which may be attributable to inhibition of adiponectin gene transcription. There are several mechanisms through which adiponectin may decrease the risk of type 2 diabetes, including suppression of hepatic gluconeogenesis, stimulation of fatty acid oxidation in the liver, stimulation of fatty acid oxidation and glucose uptake in skeletal muscle, and stimulation of insulin secretion. To date, no systematic review has been conducted that evaluate the potential importance of adiponectin metabolism in insulin resistance. In this review attempt has been made to explore the relevance of adiponectin metabolism for the development of diabetes mellitus. This article also identifies this novel target for prospective therapeutic research aiming successful management of diabetes mellitus. | Kakali Ghoshal Maitree Bhattacharyya | 2015 | World Journal of Diabetes2015，6，1： | 20 |
| 2 | System dynamic modelling to assess economic viability and risk trade-offs for ecological restoration in South Africa显示文摘 | D.J. Crookes J.N. Blignaut M.P. de Wit K.J. Esler D.C. Le Maitre S.J. Milton S.A. Mitchell J. Cloete P. de Abreu H. Fourie (nee Vlok) K. Gull D. Marx W. Mugido T. Ndhlovu M. Nowell M. Pauw A. Rebelo | 2013 | Journal of Environmental Management2013，，： | 2 |
| 3 | 1-Hydroxypyrene and 3-hydroxybenzo[ a ]pyrene as biomarkers of exposure to PAH in various environmental exposure situations显示文摘 | Ariane Leroyer Fanny Jeandel Anne Maitre Mike Howsam Dominique Deplanque Muriel Mazzuca Catherine Nisse | 2009 | Science of the Total Environment2009，，5： | 1 |
| 4 | Localization of degradative enzymes and their inhibitors in the degenera te human intervertebral disc显示文摘 | Le Maitre CL Freemont AJ Hoyland JA | | 0，，： | 1 |
| 5 | Current understanding of cellular and molecular events in intervertebral disc degeneration:implications for therapy显示文摘 | Freemont A J Watkins A Le Maitre C | | 0，，： | 1 |
| 6 | Testing a climato-topographic index for predicting wetlands distribution along an European climate gradient显示文摘 | Ph. Merot H. Squividant P. Aurousseau M. Hefting T. Burt V. Maitre M. Kruk A. Butturini C. Thenail V. Viaud | 2002 | Ecological Modelling2002，，1： | 1 |
| 7 | Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc显示文摘 | Le Maitre CL Freemont AJ Hoyland JA | | 0，，01： | 1 |
| 8 | Forest evaporation models:Relationships between stand growth and evaporation显示文摘 | Le Maitre DC Versfeld DB | | 0，，： | 1 |
| 9 | Assessment of phenolic content and free radical-scavenging capacity of some Thai indigenous plants 显示文摘 | Maisuthisakul Pitchaon Suttajit Maitree Pong-sawatmanit Rungnaphar | 2007 | Food Chemis- try2007，100，4： | 1 |
| 10 | The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration显示文摘 | Le Maitre CL Freemont AJ Hoyland JA | | 0，，： | 1 |
| 11 | Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc显示文摘 | Hoyland JA Le Maitre C Freemont AJ | | 0，，： | 1 |
| 12 | Theoretical study of the first transition row oxides and sulfides显示文摘 | Charles W. Bauschlicher Phillippe Maitre | 1995 | Theoretica Chimica Acta (-)1995，，2： | 1 |
| 13 | 查看详情显示文摘 | Hagley E Maitre X Nogues G Wunderlich C Brune M Raimond J M Haroche S | | 0，，： | 1 |
| 14 | Early prediction of cerebral palsy after neonatal intensive care usirng motor development trajectories in infancy显示文摘 | Maitre NL Slaughter JC Aschner JL | | 0，，10： | 1 |
| 15 | The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration显示文摘 | Le Maitre CL Freemont AJ Hoyland JA | | 0，，04： | 1 |
| 16 | Accelerated cellular senescence in degenerate intervertebral discs:a possible role in the pathogenesis of intervertebral disc degeneration显示文摘 | Le Maitre CL Freemont AJ Hoyland JA | | 0，，： | 1 |
| 17 | Loca lization of degradative enzymes and their inhibitors in the degenera te human intervertebral disc显示文摘 | Le Maitre CL Freemont AJ Hoyland JA | | 0，，： | 1 |
| 18 | Evaporation heat transfer and pressure drop of HFC-134a in a helically coiled concentric tube-in-tube heat exchanger显示文摘 | Somchai Wongwises Maitree Polsongkram | 2005 | International Journal of Heat and Mass Transfer2005，，3： | 1 |
| 19 | Matrix synthe sis and degradation in human intervertebral disc degeneration显示文摘 | Le Maitre CL Pockert A Buttle DJ | | 0，，： | 1 |
| 20 | Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc显示文摘 | Christine LynLe Maitre Anthony JFreemont Judith AlisonHoyland | 2004 | J Pathol2004，，1： | 1 |
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