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| 1 | Colorectal cancer screening:20 years of development and recent progress显示文摘Colorectal cancer(CRC)is the second most common cancer in Europe and its incidence is steadily increasing.This trend could be reversed through timely secondary prevention(screening).In the last twenty years,CRC screening programs across Europe have experienced considerable improvements(fecal occult blood testing;transition from opportunistic to population based program settings).The Czech Republic is a typical example of a country with a long history of nationwide CRC screening programs in the face of very high CRC incidence and mortality rates.Each year,approximately 8000 people are diagnosed with CRC and some 4000 die from this malignancy.Twenty years ago,the first pilot studies on CRC screening led to the introduction of the opportunistic Czech National Colorectal Cancer Screening Program in 2000.Originally,this program was based on the guaiac fecal occult blood test(FOBT)offered by general practitioners,followed by colonoscopy in cases of FOBT positivity.The program has continuously evolved,namely with the implementation of immunochemical FOBTs and screening colonoscopy,as well as the involvement of gynecologists.Since the establishment of the Czech CRC Screening Registry in 2006,2405850 FOBTs have been performed and 104565 preventive colonoscopies recorded within the screening program.The overall program expanded to cover 25.0%of the target population by 2011.However,stagnation in the annual number of performed FOBTs lately has led to switching to the option of a population-based program with personal invitation,which is currently being prepared. | Miroslav Zavoral Stepan Suchanek Ondrej Majek Premysl Fric Petra Minarikova Marek Minarik Bohumil Seifert Ladislav Dusek | 2014 | World Journal of Gastroenterology2014，20，14： | 16 |
| 2 | How significant is the association between metabolic syndrome and prevalence of colorectal neoplasia?显示文摘The incidence and prevalence of metabolic syndrome(MS) and colorectal cancer(CRC) has been rising in developed countries. The association between these two diseases has been widely studied and reported. Less evidence is available about the relationship between MS and CRC precancerous lesions(adenomatous polyps, adenomas). The aim of this paper is to present an overview of our scientific understanding of that topic and its implication in clinical practice. One of the principal goals of current CRC secondary prevention efforts is to detect and remove the precancerous lesions in individuals with an average CRC risk to prevent the development of invasive cancer. MS is not currently considered a high-risk CRC factor and is therefore not included in the guidelines of organized screening programs. However, in light of growing scientific evidence, the approach to patients with MS should be changed. Metabolic risk factors for the development of adenomas and cancers are the same- obesity, impaired glucose tolerance, dyslipidemia, hypertension, cardiovascular diseases and diabetes mellitus type 2. Therefore, the key issue in the near future is the development of a simple scoring system, easy to use in clinical practice, which would identify individuals with high metabolic risk of colorectal neoplasia and would be used for individual CRC secondary prevention strategies. Currently, such scoring systems have been published based on Asian(Asia-Pacific Colorectal Screening Score; APCS) and Polish populations. | Stepan Suchanek Tomas Grega Ondrej Ngo Gabriela Vojtechova Ondrej Majek Petra Minarikova Nagyija Brogyuk Bohus Bunganic Bohumil Seifert Ladislav Dusek Miroslav Zavoral | 2016 | World Journal of Gastroenterology2016，22，36： | 10 |
| 3 | Survival from colorectal cancer in Germany in the early 21st century 显示文摘 | Majek O Gondos A Jansen L | 2012 | The British journal of cancer2012，06，11： | 1 |
| 4 | Classification of brandies and wine distillates using front face fluorescence spectroscopy 显示文摘 | Jana Sadecka Jana Tothova Pavel Majek | 2009 | Food Chemistry2009，117，3： | 1 |
| 5 | Tubal ligation and the risk of ovarian cancer:review and meta-analysis 显示文摘 | Cibula D Widschwendter M Majek O | 2011 | Hum Reprod Update2011，17，1： | 1 |
| 6 | Classification of South African red and white wines according to grape variety based on the non-coloured phenolic content 显示文摘 | Andre de Villiers Pavel Majek | 2005 | Eur Food Res Technol2005，221，： | 1 |
| 7 | Enteroviruses in water environment-a potential threat to public health 显示文摘 | Rajtar B Majek M Polanski L | 2008 | Ann Agricul Environ Med: AAEM2008，15，2： | 1 |
| 8 | Stir bar sorptive extraction combined with GC-MS analysis and chemometric methods for the classification of South African Wines according to the volatile composition显示文摘 | TREDOUX A DE VILLIERS A MAJEK P LYNEN F CROUCH A SANDRA P | 2008 | Agric Food Chem2008，56，12： | 1 |
| 9 | Prognostic value of scores based on malnutrition or systemic inflammatory response in pa- tients with metastatic or recurrent gastric cancer显示文摘 | Sachlova M Majek O Tucek S | 2014 | Nutr Canc- er2014，66，8： | 1 |
| 10 | Determination of anthocyanins in wine by direct injection liquid chromatography- diode array detection-mass spectrometry and classification of wines using discriminant analysis 显示文摘 | Villiers A d Vanhoenacker G Majek P | 2004 | Journal of Chromatography A2004，1054，12： | 1 |
| 11 | Classification of brandies and wine distillates using front face fluorescence spectroscopy 显示文摘 | Sadecka J Tothova J Majek P | 2009 | Food Chemistry2009，，： | 1 |
| 12 | Enteroviruses in water environment--a potential threat to public health 显示文摘 | Rajtar B Majek M Polafiski L Polz-Dacewicz M | 2008 | Ann Agric Environ Med2008，15，2： | 1 |
| 13 | Colorectal cnncer screening: 20 years of development and recent progress 显示文摘 | Zavoral M Suchanek S Majek O | 2014 | World J Gastroenterol2014，20，14： | 1 |
| 14 | Chemometric studies in capillary gas-chromatographic separation of hydrocarbons in coupled columns显示文摘 | MAJEK P | 2005 | Journal of Chromatography A2005，1068，： | 1 |
| 15 | Proteomic analysis of plasma samples from acute coronary syndrome patients-the pilot study显示文摘 | Maly MA Majek P Reicheltova Z | | 0，，01： | 1 |
| 16 | Oncological outcomes ofnerve-sparing radical hysterectomy for cervical cancer: asystematic review显示文摘 | Basaran D Dusek L Majek 0 | 2015 | Ann Surg Oncol2015，22，9： | 1 |
| 17 | Determination of anthocyanins in wine by direct injection liquid chromatography diode array detection mass spectrometry and classification of wines using discriminant analysis显示文摘 | de Villiers A Vanhoenacker G Majek P | 2004 | Journal of Chromatography A2004，1054，： | 1 |
| 18 | Simultaneous determination of caffeine, caramel and riboflavin in cola-type and energy drinks by synchronous fluorescence technique coupled with partial least squares显示文摘 | Ziak L Majek P Hrobonova K | 2014 | Food Chem2014，159，： | 1 |
| 19 | Enteroviruses in water environment-a potential threat to public health 显示文摘 | RAJTAR B MAJEK M POLANSKI L | 2008 | Ann Agr Environ Med: AAEM2008，15，2： | 1 |
| 20 | GC separation of 2-substituted ethyl propionate enantiomers on permethylated and 2,6-dimethyl-3-pentylβ-andγ-cyclodextrin stationary phases显示文摘 | Spanik I Zebrowski W Majek P | | 0，，12： | 1 |
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