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| 1 | Strength evolution and deformation behaviour of cemented paste backfill at early ages: Effect of curing stress, filling strategy and drainage显示文摘In this study, a pressure cell apparatus is developed to investigate the early age evolution of the strength and deformation behaviour of cemented paste backfill(CPB) when subjected to various loading conditions under different curing scenarios. The different curing scenarios that are simulated include:(1)drained and undrained conditions,(2) different filling rates,(3) different filling sequences, and(4) different curing stresses. The findings show that drainage, curing stress, curing time and filling rate influence the mechanical and deformation behaviours of CPB materials. The coupled effects of consolidation, drainage and suction contribute to the strength development of drained CPB subjected to curing stress. On the other hand, particle rearrangement caused by the applied pressure and suction development due to self-desiccation plays a significant role in the strength gain of undrained CPB cured under stress.Furthermore, curing stress induces slightly faster rate of cement hydration, which can contribute to strength acquisition. | Ghirian Alireza Fall Mamadou | 2016 | International Journal of Mining Science and Technology2016，26，5： | 17 |
| 2 | Role of Nrf2 in chronic liver disease显示文摘Nuclear erythroid 2-related factor 2(Nrf2) is a central regulator of antioxidative response elements-mediated gene expression. It has a significant role in adaptive responses to oxidative stress by interacting with the antioxidant response element, which induces the expression of a variety of downstream targets aimed at cytoprotection. Previous studies suggested oxidative stress and associated damage could represent a common link between different forms of diseases. Oxidative stress has been implicated in various liver diseases, including viral hepatitis, nonalcoholic fatty liver disease/steatohepatitis, alcoholic liver disease and drug-induced liver injury. Nrf2 activation is initiated by oxidative or electrophilic stress, and aids in the detoxification and elimination of potentially harmful exogenous chemicals and their metabolites. The expression of Nrf2 has been observed throughout human tissue, with high expression in detoxification organs, especially the liver. Thus, Nrf2 may serve as a major regulator of several cellular defense associated pathways by which hepatic cells combat oxidative stress. We review the relevant literature concerning the crucial role of Nrf2 and its signaling pathways against oxidative stress to protect hepatic cell from oxidative damage during development of common chronic liver diseases. We also review the use of Nrf2 as a therapeutic target to prevent and treat liver diseases. | Wei Tang Yong-Fang Jiang Murugavel Ponnusamy Mamadou Diallo | 2014 | World Journal of Gastroenterology2014，20，36： | 14 |
| 3 | 接受48周高效抗逆转录病毒治疗的艾滋病患者细胞内HIVDNA定量检测及其意义显示文摘目的观察中国艾滋病患者外周血T淋巴细胞及单核细胞作为HIV—1病毒储存库的情况,了解其在接受48周高效抗逆转录病毒治疗(HAART)中的动态变化及其临床意义。方法35例慢性HIV-1感染的成人在初治HAART的0、24、48周,使用流式细胞仪测定血T淋巴细胞亚群数量,使用磁珠分选法从外周血单个核细胞中分离T淋巴细胞和单核细胞并提取细胞DNA,采用实时荧光定量RT—PCR法检测血清HIVRNA、用SYBRGreen实时PCR对T淋巴细胞和单核细胞内的前病毒HIVDNA载量进行定量测定;使用SPSS18.0软件对收集的数据进行分析。结果35例艾滋病患者在HAART初次启动的0、24、48周,外周血HIVRNA水平分别为(4.12±1.41)、≤1.69、≤1.69lg拷贝/ml,CD4+T淋巴细胞数分别为(196±101)、(321±112)、(392±127)个/μl;在T淋巴细胞中HIVDNA水平分别为(4.03±0.53)、(2.74±1.16)、(2.45±0.41)lg拷贝/106细胞,在单核细胞中HIVDNA水平分别为(2.51±0.68)、(2.16±0.34)、(2.03±0.25)lg拷贝/106细胞。统计学分析显示,在48周HAART过程中,外周血HIVRNA水平与CD4T淋巴细胞数呈负相关,与T淋巴细胞及单核细胞中的前病毒HIVDNA水平均呈正相关;T淋巴细胞中的HIVDNA下降速度慢于单核细胞;外周血CD4+T淋巴细胞与T淋巴细胞前病毒HIVDNA载量呈负相关。结论HIV感染者T淋巴细胞和单核细胞均可作为HIV病毒储存库,而淋巴细胞是更主要的储存库细胞;细胞内HIVDNA水平与血HIVRNA水平变化正相关,与血CD4T淋巴细胞数呈负相关,T淋巴细胞内前病毒HIVDNA水平变化可能作为HAART中AIDS病程进展的观察指标之一。 | 郑煜煌 Diallo Mamadou Alius 陈霞 何艳 贺波 贺梅 王红艳 肖水灵 罗艳 姚运海 林一鹤 谌资 周华英 | 2012 | 中华内科杂志2012，51，9： | 8 |
| 4 | 分子标记辅助选择改良水稻恢复系R1005的褐飞虱抗性显示文摘以抗褐飞虱材料B5(携带Bph14和Bph15基因)为供体亲本,水稻优良恢复系R1005为受体亲本,通过杂交、回交和分子标记辅助选择技术,将Bph14和Bph15基因同时导入到R1005中,经过农艺性状选择和褐飞虱抗性鉴定,选育出3个携带Bph14和Bph15基因的纯合株系CY11711-14、CY11712-5和CY11714-100。苗期褐飞虱抗性鉴定结果表明,3个株系对褐飞虱表现高抗水平,田间生育期观察、主要农艺性状考查及稻米品质分析表明,株系CY11712-5和CY11714-100与受体亲本R1005没有显著差异,可以代替R1005用于抗褐飞虱恢复系使用。以3个育成株系为父本与3个不育系Q2A、天丰A和川农1A配制杂交组合进行苗期褐飞虱抗性鉴定,结果显示Bph14、Bph15基因在杂合状态下表现不抗褐飞虱。结果表明Bph14和Bph15基因在本试验中不表现显性效应。 | 闫成业 MAMADOU Gandeka 朱子建 牟同敏 | 2014 | 华中农业大学学报2014，33，5： | 7 |
| 5 | 分子标记辅助选择改良杂交水稻组合Q优6号的白叶枯病抗性显示文摘杂交水稻组合Q优6号是长江中下游稻区大面积推广的中熟三系杂交中稻组合,对白叶枯病抗性较差。本研究采用杂交、回交和分子标记辅助选择技术,将广谱抗性基因Xa23渗入到恢复系R1005中,综合农艺性状选择和Xa23基因分子标记选择,获得1份具有Xa23基因的优良株系CY11701-4。对该株系和以Q2A为母本配制的组合进行白叶枯病抗性鉴定,结果表明CY11701-4及Q2A/CY11701-4对接种的7个菌株(PXO61,PXO99,ZHE173,GD1358,FuJ,YN24和HeN11)均表现高抗水平。经主要农艺性状、产量和主要稻米品质指标测定分析,CY11701-4与R1005没有显著差异,Q2A/CY11701-4与Q优6号主要农艺性状没有显著差异,播始历期缩短1.3 d,产量显著提高。 | 闫成业 仲雪婷 Gandeka Mamadou 牟同敏 | 2013 | 分子植物育种2013，11，6： | 4 |
| 6 | Chemically induced changes in the geotechnical response of cementing paste backfill in shaking table test显示文摘Cemented paste backfill(CPB)is extensively used for underground mine support and/or tailings management.However,CPB behavior under cyclic loadings might be affected by the chemistry of its porewater,which often contains sulphate ions.Till today,no studies have addressed the effect of sulphate on the response of CPB to cyclic loadings by using shaking table technique.This study presents new findings of assessing the effect of the sulphate in the pore water of CPB on its geotechnical response to cyclic loading by using shaking table.CPB mixtures were prepared(with and without sulphate),poured into a flexible laminar shear box,cured to 4 h,and then exposed to cyclic loading using one-dimensional(1D)shaking table.Several parameters(e.g.pore water pressure,settlement,lateral deformation,acceleration,electrical conductivity,effective stress,and liquefaction susceptibility)were monitored or determined before,during,and after shaking.Obtained results indicate that the sulphate-bearing CPB cured to 4 h can be prone to liquefaction under the studied conditions.However,sulphate-free CPB samples are resistant to liquefaction.These results are expected to contribute to a better understanding of the effect of water chemistry on the cyclic behavior of CPB,consequently enhancing the cost-effective design of CPB structures. | Imad Alainachi Mamadou Fall | 2021 | Journal of Rock Mechanics and Geotechnical Engineering2021，13，3： | 4 |
| 7 | Introgression of Two Drought QTLs into FUNAABOR-2 Early Generation Backcross Progenies Under Drought Stress at Reproductive Stage显示文摘FUNAABOR-2 is a popular Ofada rice variety grown in a large area under rainfed upland condition across western states of Nigeria. We used the combination of phenotypic and marker-assisted selection(MAS) to improve grain yield of FUNAABOR-2 under drought stress(DS) at the reproductive stage via introgression of two drought quantitative trait loci(QTLs), qDTY12.1 and qDTY2.3. Foreground selection was carried out using peak markers RM511 and RM250, associated with qDTY12.1 and qDTY2.3, respectively, followed by recombinant selection with RM28099 and RM1261 distally flanking qDTY12.1. Furthermore, BC1 F2-derived introgressed lines and their parents were evaluated under DS and non-stress(NS) conditions during the 2015–2016 dry season. Overall reduction of grain yield under DS compared to NS was recorded. Introgressed lines with qDTY12.1 and qDTY2.3 combinations showed higher yield potential compared to lines with single or no QTL under DS, indicating significant positive interactions between the two QTLs under the FUNAABOR-2 genetic background. Pyramiding of qDTY12.1 and qDTY2.3 in the FUNAABOR-2 genetic background led to higher grain yield production under DS and NS. | Christian Okechukwu ANYAOHA Mamadou FOFANA Vernon GRACEN Pangirayi TONGOONA Semon MANDE | 2019 | Rice science2019，26，1： | 3 |
| 8 | 耐亚胺培南铜绿假单胞菌oprD2基因与金属酶的检测显示文摘目的研究oprD2基因与金属酶(MBL)在亚胺培南耐药机制中的作用。方法对天津地区3所综合医院临床分离60株亚胺培南耐药的铜绿假单胞菌,以2-巯基乙醇(2-MPA)为酶抑制剂,在MH平皿上用纸片扩散法进行抗生素协同敏感性检测,并用PCR检测MBL基因和oprD2基因。结果60株临床分离的耐亚胺培南铜绿假单胞菌(imipenem-resistant Pseudomonas aeruginosa,IRPA)中,2-MPA方法筛选出15株(25%)MBL阳性;以PCR方法检测,22株(36.4%)oprD2基因阳性,19株(31.7%)产生IMP-1型MBL,未发现VIM-2与IMP-2酶,7株IRPA同时含有IMP-1和oprD2基因。结论IMP-1为天津地区IRPA产MBL的主要类型,也是临床分离铜绿假单胞菌亚胺培南耐药的重要原因之一。 | Diallo Mamadou Cherif 魏殿军 曹阳 马全玲 刘扬 门昆 武大伟 | 2008 | 中国感染与化疗杂志2008，8，5： | 2 |
| 9 | A column study of the hydro-mechanical behavior of mature fine tailings under atmospheric drying显示文摘In this paper, the hydro-mechanical behavior and physical properties of mature fine tailings(MFT) under atmospheric drying are investigated through a column study. In the study, evaporation takes place in the development of suction in the upper parts of the column and increasing suction leads to higher strength in the tailings. After 5 days, the suction in the first lift is around 17 k Pa in the upper part of the column.When a second lift is added, the first lift initially loses strength but over a 30 days' period, the strength is recovered to its prior value and suction in the second lift reaches 500 k Pa. The vane shear strength values show a substantial increase in the strength of the MFT after 30 days under atmospheric drying and drainage. The 90% strength found in the column exceeds the threshold(5 k Pa). The hydraulic-mechanical properties of the deposited tailings are closely coupled due to several mechanisms, such as evaporation,drainage, self-consolidation, suction and crack development. The findings of this study will provide a better understanding of the placement behavior of multiple lifts of MFT and thus contribute to reclamation design standards and reduce the use of dedicated disposal areas. | Anis Roshani Mamadou Fall Kevin Kennedy | 2017 | International Journal of Mining Science and Technology2017，27，2： | 2 |
| 10 | Geotechnical characterization of peat-based landfill cover materials显示文摘Natural methane(CH_4) oxidation that is carried out through the use of landfill covers(biocovers) is a promising method for reducing CH_4 emissions from landfills.Previous studies on peat-based landfill covers have mainly focused on their biochemical properties(e.g.CH_4 oxidation capacity).However,the utilization of peat as a cover material also requires a solid understanding of its geotechnical properties(thermal,hydraulic,and mechanical),which are critical to the performance of any biocover.Therefore,the objective of this context is to investigate and assess the geotechnical properties of peat-based cover materials(peat,peat-sand mixture),including compaction,consolidation,and hydraulic and thermal conductivities.The studied materials show high compressibility to the increase of vertical stress,with compression index(C_c) values ranging from 0.16 to 0.358.The compressibility is a function of sand content such that the peat-sand mixture(1:3) has the lowest C_c value.Both the thermal and hydraulic conductivities are functions of moisture content,dry density,and sand content.The hydraulic conductivity varies from 1.74 × 10^(-9) m/s to 7.35 × 10^(-9) m/s,and increases with the increase in sand content.The thermal conductivity of the studied samples varies between 0.54 W/(m K) and 1.41 W/(m K) and it increases with the increases in moisture and sand contents.Increases in sand content generally increase the mechanical behavior of peat-based covers;however,they also cause relatively high hydraulic and thermal conductivities which are not favored properties for biocovers. | Afshin Khoshand Mamadou Fall | 2016 | Journal of Rock Mechanics and Geotechnical Engineering2016，8，5： | 2 |
| 11 | Natural History of Pediatric Crohn’s Disease: A Population-Based Cohort Study显示文摘 | Gwenola Vernier–Massouille Mamadou Balde Julia Salleron Dominique Turck Jean Louis Dupas Olivier Mouterde Véronique Merle Jean Louis Salomez Julien Branche Raymond Marti éric Lerebours Antoine Cortot Corinne Gower–Rousseau Jean Frédéric Colombel | 2008 | Gastroenterology2008，，4： | 2 |
| 12 | 蜂巢轻质墙体结构与自承重结构体系研究与应用显示文摘2009年,经多学科专家评审,上海建筑建材业市场管理总站发行了我国第一本《海尔斯蜂巢轻质墙体建筑结构》产品推荐性应用图集(2009沪J/T-147)。并以沪建市管(2009)31号文通知各大建筑设计院和建设市场单位推广应用,先后在江、浙地区备案。201O年上海世博会上集中推介与科普宣传了该高科技仿生低碳的建材产品。各地的工程示范应用,也扩大其行业的认知度,蜂巢轻质墙体项目建设正在国内9t4ia然兴起。 | 邱玉东 Mamadou Bobo BALDE | 2013 | 建设科技2013，，21： | 2 |
| 13 | An Institutional Innovation for Agricultural Technology Adaptation and Adoption: Rice in West and Central Africa显示文摘 | Sidi Sanyang Moussa Sie Aliou Diagne Marie-Noelle Ndjiondjop Dogbe Selome Yawovi Mamadou MBare Coulibaly Patrice Ygue Adegbola | 2012 | Journal of Sociology Study2012，2，11： | 1 |
| 14 | Comparison of an Organophosphate Insecticide with a Mycoinsectieide or the Control of Oedaleus senegalensis (Orthoptera: Acrididae) and Other Sahelian Grasshoppers at an Operational Scale显示文摘 | LANGEWALD J OUAMBAMA Z MAMADOU A | 1999 | Biocontrol Sci Technol1999，，9： | 1 |
| 15 | The thalamostriatal system: a highly specific network of the basal ganglia circuitry显示文摘 | Yoland Smith Dinesh V. Raju Jean-Francois Pare Mamadou Sidibe | 2004 | Trends in Neurosciences2004，，9： | 1 |
| 16 | A multiphysics-viscoplastic cap model for simulating blast response of cemented tailings backfill显示文摘Although a large number of previous researches have significantly contributed to the understanding of the quasi-static mechanical behavior of cemented tailings backfill,an evolutive porous medium used in underground mine cavities,very few efforts have been made to improve the knowledge on its response under sudden dynamic loading during the curing process.In fact,there is a great need for such information given that cemented backfill structures are often subjected to blast loadings due to mine exploitations.In this study,a coupled thermo-hydro-mechanical-chemical(THMC)-viscoplastic cap model is developed to describe the behavior of cementing mine backfill material under blast loading.A THMC model for cemented backfill is adopted to evaluate its behavior and evolution of its properties in curing processes with coupled thermal,hydraulic,mechanical and chemical factors.Then,the model is coupled to a Perzyna type of viscoplastic model with a modified smooth surface cap envelope and a variable bulk modulus,in order to reasonably capture the nonlinear and rate-dependent behaviors of the cemented tailings backfill under blast loading.All of the parameters required for the variable-modulus viscoplastic cap model were obtained by applying the THMC model to reproducing evolution of cemented paste backfill(CPB)properties in the curing process.Thus,the behavior of hydrating cemented backfill under high-rate impacts can be evaluated under any curing time of concern.The validation results of the proposed model indicate a good agreement between the experimental and the simulated results.The authors believe that the proposed model will contribute to a better understanding of the performance of hydrating cemented backfill under blasting,and also to practical risk management of backfill structures associated with such a dynamic condition. | Gongda Lu Mamadou Fall Liang Cui | 2017 | Journal of Rock Mechanics and Geotechnical Engineering2017，9，3： | 1 |
| 17 | Involvement of dopamine loss in extrastriatal basal ganglia nuclei in the pathophysiology of Parkinson's disease 显示文摘 | Benazzouz A Mamad O Abedi P | 2014 | Front Aging Neurosci2014，6，： | 1 |
| 18 | Changes in soluble carbohydrates,lipid peroxidation and antioxidant enzyme activities in the embryo during aging in wheat grains显示文摘 | LEHNER A MAMADOU N POELS P | 2008 | Journal of Cereal Science2008，47，： | 1 |
| 19 | Oil extraction from coriander fruits by extrusion and comparison with solvent extraction processes显示文摘 | Jazia S Thierry T Mamadou F | 2011 | Industrial crops and products2011，，33： | 1 |
| 20 | Red wine polphenols prevent angiotensin Ⅱ-induced hypertension and endothelial dysfunction in rats ; role of NADPH oxidase 显示文摘 | Mamadou S Malta C Sandrine M | 2006 | Cardiovasc Res2006，71，： | 1 |
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