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| 1 | Plasma free amino acid profiling of esophageal cancer using high-performance liquid chromatography spectroscopy显示文摘AIM:To perform plasma free amino acid(PFAA)profiling of esophageal squamous cell carcinoma(ESCC)patients at different pathological stages and healthy subjects.METHODS:Plasma samples from ESCC patients(n=51)and healthy control adults(n=60)were analyzed by high-performance liquid chromatography(HPLC).The ESCC patients included moderate/poorly-differentiation(n=24),lymph node metastasis(n=17)and clinical stage>Ib2(n=36).Partial least squares discriminant analysis was performed to demonstrate that the PFAA metabolic patterns enabled discrimination between ESCC patients and controls,and the Student t test was applied to assess significant differences in PFAA concentrations between the two groups.RESULTS:There were significant differences in the PFAA profiles between controls and ESCC patients.Compared with healthy controls,the levels of Asp,Glu,Gly,His,Thr,Tau,Ala,Met,Ile,Leu,and Phe were decreased in ESCC patients,but Cys was increased.There exists a strong correlation between PFAA profiles and clinicopathological characteristics in ESCC patients.The levels of many PFAAs(i.e.,Glu,Asp,Ser,Gly,Tau,Ala,Tyr,Val,Ile,and Leu)were related to pathological grading,lymph node metastasis,and ESCC clinical stage.Very good discrimination between ESCC patients and control subjects was achieved by multivariate modeling of plasma profiles.CONCLUSION:HPLC-based plasma profiling analysis was shown to be an effective approach to differentiate between ESCC patients and controls.PFAA profiles may have potential value for screening or diagnosing ESCC. | Hong Ma Ayshamgul Hasim Batur Mamtimin Bin Kong Hai-Ping Zhang Ilyar Sheyhidin | 2014 | World Journal of Gastroenterology2014，20，26： | 11 |
| 2 | Near-surface sand-dust horizontal flux in Tazhong-the hinterland of the Taklimakan Desert显示文摘Tazhong is the hinterland and a sandstorm high-frequency area of the Taklimakan Desert. However, little is known about the detailed time-series of aeolian sand transport in this area. An experiment to study the sand-dust horizontal flux of near-surface was carried out in Tazhong from January to December 2009. By measuring the sand-dust horizontal flux throughout sixteen sand-dust weather processes with a 200-cm tall Big Spring Number Eight (BSNE) sampler tower, we quantitatively analyzed the vertical variation of the sand-dust horizontal flux. And the total sand-dust horizontal flux of different time-series that passed through a section of 100 cm in width and 200 cm in height was estimated combining the data of saltation movement continuously recorded by piezoelectric saltation sensors (Sensit). The results indicated that, in the surface layer ranging from 0-200 cm, the intensity of sand-dust horizontal flux decreased with the increase of the height, and the physical quantities obeyed power function well. The total sand-dust horizontal flux of the sixteen sand-dust weather processes that passed through a section of 100 cm in width and 200 cm in height was about 2,144.9 kg, the maximum of one sand-dust weather event was about 396.3 kg, and the annual total sand-dust horizontal flux was about 3,903.2 kg. The high levels of aeolian sand transport occurred during daytime, especially from 13:00 to 16:00 in the afternoon. We try to develop a new method for estimation of the detailed time-series of aeolian sand transport. | XingHua YANG Qing HE Mamtimin ALI Wen HUO XinChun LIU | 2013 | Journal of Arid Land2013，5，2： | 11 |
| 3 | Impact factors of soil wind erosion in the center of Taklimakan Desert显示文摘The development and progress of soil wind erosion are influenced by the factors of climate,terrain,soil and vegetation,etc. This paper,taking Tazhong region,a town in the centre of the Taklimakan Desert,as an example and using comparative and quantitative methods,discussed the effects of climate,surface roughness(including vegetation cover) and surface soil properties on soil wind erosion. The results showed that the climate factor index C of annual wind erosion is 28.3,while the maximum of C is 13.9 in summer and it is only 0.7 in winter. The value of C has a very good exponential relationship with the wind speed. In Tazhong region,the surface roughness height is relatively small with a mean of 6.32 × 10-5 m,which is in favor of soil wind erosion. The wind erosion is further enhanced by its sandy soil types,soil particle size,lacking of vegetation and low soil moisture content. The present situation of soil wind erosion is the result of concurrent effects of climate,vegetation and surface soil properties. | Qing HE XingHua YANG Ali Mamtimin ShiHao TANG | 2011 | Journal of Arid Land2011，3，1： | 8 |
| 4 | Diurnal dynamics of soil respiration and the influencing factors for three land-cover types in the hinterland of the Taklimakan Desert,China显示文摘Knowledge of soil respiration and the influencing factors in desert ecosystems is essential to understanding carbon dynamics and responses of biotic and abiotic processes in soils to climate change. In this study, soil respiration rate(R_s) for three land-cover types(shifting sandy land, sandy land with straw checkerboard barriers, and shelter forest land) in the hinterland of the Taklimakan Desert was measured in May 2015 using an automated soil CO_2 flux system. The effects of soil temperature(T_s) and soil water content(W_s) on R_s were also analyzed. The results showed that R_s values in shifting sandy land, sandy land with straw checkerboard barriers, and shelter forest land were all low and exhibited obvious diurnal fluctuations. The establishment of straw checkerboard barriers in sandy land had no significant effect on R_s, while the establishment of shelterbelts significantly increased R_s. Shifting sandy land and sandy land with straw checkerboard barriers were carbon sinks at night and early morning and were carbon sources in the daytime, while shelter forest land always acted as a carbon source during the whole day. The synergistic effect of T_s and W_s could better explain the diurnal dynamics in R_s than single factor. In shifting sandy land and sandy land with straw checkerboard barriers, W_s was identified as a limiting factor influencing the diurnal dynamics of R_s. Furthermore, a relatively strong hysteresis loop existed between R_s and T_s. In contrast, in shelter forest land, R_s was significantly influenced by T_s, and a relatively weaker hysteresis loop existed between R_s and W_s. | YANG Fan ALI Mamtimin ZHENG Xinqian HE Qing YANG Xinghua HUO Wen LIANG Fengchao WANG Shaoming | 2017 | Journal of Arid Land2017，9，4： | 7 |
| 5 | Decreased blood riboflavin levels are correlated with defective expression of RFT2 gene in gastric cancer显示文摘AIM:To investigate the relationship between blood riboflavin levels and riboflavin transporter 2(RFT2) gene expression in gastric carcinoma(GC) development.METHODS:High-performance liquid chromatography was used to detect blood riboflavin levels in patients with GC.Real-time fluorogenic quantitative polymerase chain reaction and immunohistochemistry were used to analyze the expression of RFT2 mRNA and protein in samples from 60 GC patients consisting of both tumor and normal tissue.RESULTS:A significant decrease in the RFT2 mRNA levels was detected in GC samples compared with those in the normal mucous membrane(0.398 ± 0.149 vs 1.479 ± 0.587;P = 0.040).Tumors exhibited low RFT2 protein expression(75%,16.7%,8.3% and 0% for no RFT2 staining,weak staining,medium staining and strong staining,respectively),which was significantly lower than that in the normal mucous membrane(10%,16.7%,26.7% and 46.7% for no RFT2 staining,weak staining,medium staining and strong staining,respectively;P < 0.05).Tumors with low RFT2 expression were significantly associated with tumor stage and histological grade.Moreover,a significantly decrease in Uyghur patients was observed compared with Han patients.However,other parameters-gender,tumor location and lymph node metastasis-showed no significant relationship with RFT2 expression.Blood riboflavin levels were reverse correlated with development of GC(1.2000 ± 0.97 569 ng/mL in high tumor stage patients vs 2.5980 ± 1.31 129 ng/mL in low tumor stage patients;P < 0.05).A positive correlation of plasma riboflavin levels with defective expression of RFT2 protein was found in GC patients(2 = 2.619;P = 0.019).CONCLUSION:Defective expression of RFT2 is associated with the development of GC and this may represent a mechanism underlying the decreased plasma riboflavin levels in GC. | Maynur Eli De-Sheng Li Wei-Wei Zhang Bing Kong Chen-Song Du Maimaitiaili Wumar Batur Mamtimin Ilyar Sheyhidin Ayshamgul Hasim | 2012 | World Journal of Gastroenterology2012，18，24： | 6 |
| 6 | Sand flux estimation during a sand-dust storm at Tazhong area of Taklimakan Desert, China显示文摘In this paper, the sand transport during a sand-dust storm in the Tazhong area of the central Taklimakan Desert from 11:29 to 23:56 on July 19, 2008 was observed and measured in real time. The sand flux at Tazhong was estimated using sand transport empirical formulas. The critical friction velocity at Tazhong was 0.24 m/s and the functional relation between the wind speed and sediment discharge at the height of 2 m was established. It was also found that the calculated values by Lettau's sediment discharge formula were close to those of the instrument measurements. The horizontal sand flux and the vertical sand flux during this sand-dust storm at Tazhong were respectively 258.67×10-4 kg/(m·s) and 40.07×10-7 kg/(m2·s). | XingHua YANG XiaoLiang XU Qing HE Ali Mamtimin Bo YU ShiHao TANG | 2011 | Journal of Arid Land2011，3，3： | 6 |
| 7 | An magnetic resonance-based plasma metabonomic investigation on abnormal Savda in different complicated diseases显示文摘OBJECTIVE: To provide potential evidence for the existence of abnormal Savda, we assessed host metabonomic responses and dynamic changes occurring in various diseases using1H nuclear magnetic resonance(NMR)-based metabonomics.METHODS: Plasma samples taken from patients with complicated diseases with abnormal Savda(n=140, including 35 cases each of diabetes, asthma,breast cancer, and cervical carcinoma) and from healthy controls(n=35) were analyzed by1H NMR(600 MHz), and the spectral profiles were analyzed by multivariate analysis using orthogonal projection to latent structure with discriminant analysis.RESULTS: Supervised modeling of the data provided very good discrimination between patients and healthy controls. Compared with the healthy controls, the patient groups with different disease conditions displayed similar metabolic changes, characterized by lower creatine, creatinine, lactate, and amino acid levels(including isoleucine, leucine, valine, alanine, and 1-methylhistidine) and higher lipid levels(very low-density lipoproteins and unsaturated lipids). Additionally, cancer patients(breast and cervical) showed decreased myo-inositol,α-glucose, and β-glucose, and increased pyruvate and carnitine in plasma.CONCLUSION:The data indicate that decreased oxidative defense, liver function abnormalities, amino acid deficiencies, and energy metabolism disorders are common characteristics of complicated diseases, which may be related to the formation of abnormal Savda. | Batur Mamtimin Mawlanjan Hizbulla Nazuk Kurbantay Li You Xinghai Yan Halmurat Upur | 2014 | Journal of Traditional Chinese Medicine2014，34，2： | 5 |
| 8 | Analyses of temperature and humidity profiles and heat balance of the surface boundary-layer in the hinterland of the Taklimakan Desert显示文摘The daily variation regularities of micro-meteorological features, such as the surface layer temperature and humidity profiles of the inner desert in summer, the temperature of sand bed, the radiation of the earth's surface and the heat balance, were analyzed by combination method and logarithm regression according to the data obtained from the Atmospheric Environmental Observation Station of Taklimakan Desert in July―August of 2006 and 2007. It has been shown that temperature inversion occurred near the surface layer at night in summer, the temperature increased with the height within a certain altitude range, and the reverse was true during the daytime. The ground surface radiation balance of the Taklimakan Desert was mainly positive; other radiation components (the global radiation, the reflective radiation, the ground upward long wave radiation and the net radiation) exhibited daily variation char- acteristics evidently and showed normal diurnal cycle, except for the downward atmospheric long-wave radiation. The heat exchange of the surface layer of the desert was dominated by turbulence sensible heat, and only a small portion of heat was transferred to the atmospheric surface layer in the form of latent heat. The surface sensible heat and latent heat changed with the increase and decrease of sun elevation angle, with maximum of the latent heat appearing in wee hours and the peak value of the sensible heat appearing at noon. Observation and analysis showed that heating effect of the underlying surface of the desert was great on the aerosphere; the surface was a high heat source during the day and became a weak cold source at night. | WEI WenShou WANG MinZhong HE Qing LEI JiaQiang ALI Mamtimin | 2008 | Chinese Science Bulletin2008，53，S2： | 4 |
| 9 | Vertical distribution characteristics of dust aerosol mass concentration in the Taklimakan Desert hinterland显示文摘The different height mass concentrations of dust aerosol data from the atmosphere environment observation station(Tazhong Station)was continuously observed by instruments of Grimm 1.108,Thermo RP 1400a and TSP from January of2009 to February of 2010 in the Taklimakan Desert hinterland.Results show that:(1)The mass concentration value of 80m PM10was higher,but PM2.5and PM1.0concentrations at 80 m was obviously lower than 4 m PM10,and the value of 80 m PM1.0mass concentration was the lowest.(2)The PM mass concentrations gradually decreased from night to sunrise,with the lowest concentration at 08:00,with the mass concentration gradually increased,up to the highest concentration around18:00,and then decreased again.It was exactly the same with the changes of wind speed.(3)The high monthly average mass concentration of TSP mainly appeared from March to September,and the highest concentration was in April and May,subsequently gradually decreased.Also,March–September was a period with high value area of PM monthly average mass concentration,with the highest monthly average mass concentration of 846.0μg/m3for 4 m PM10appeared in May.The concentration of PM10was much higher than those of PM2.5and PM1.0at 80 m.There is a small difference between the concentration of PM2.5and PM1.0.Dust weather was the main factor which influenced the concentration content of the different diameter dust aerosol,and the more dust weather days,the higher content of coarse particle,conversely,fine particle was more.(4)The mass concentration of different diameter aerosols had the following sequence during dust weather:clear day | XinChun Liu YuTing Zhong Qing He XingHua Yang Ali Mamtimin Wen Huo | 2013 | Research in Cold and Arid Regions2013，5，6： | 3 |
| 10 | Analysis of mass concentration of atmospheric particulate matter in a sandstorm course and its affecting factors in the Taklimakan Desert显示文摘During the course of a major sandstorm from April 17 to April 23,2008 in the Taklimakan Desert,data pertaining to the mass concentrations of different-sized atmospheric particulate matter were observed continuously with Grimm 1.108,Thermo RP 1400a,TSP,and CAWS-600 instruments.The results showed that:(1) during the entire sandstorm process there were some differences between the daily mean particle concentration peaks and the hourly mean particle concentration peaks because the actual sandstorm lasted for only about 4 hr,whereas more particles were accumulated in the floating dust days before and after the actual sandstorm;(2) the intensity of the sandstorm was enhanced with the increase of wind speed,and this was related to the peak mass concentrations of atmospheric particulate matter;the wind speed directly affected the concentration of atmospheric particulate matter:the higher the wind speed,the higher the mass concentration(>0.23 μm was 39,496.5 μg/m 3,and >20.0 μm was 5,390.7 μg/m 3);(3) the concentration changes of PM 10 and TSP were also related to the course and intensity of the sandstorm;and(4) the mass concentration of atmospheric particulate matter had the following sequence during the dust weather:clear day < floating dust < floating and blowing dust < sandstorm.Temperature,relative humidity,and barometric pressure are important factors affecting the strength of storms,which could also indirectly affect the concentration change of atmospheric particulate matter. | XinChun Liu YuTing Zhong Qing He XingHua Yang Ali Mamtimin Wen Huo | 2012 | Research in Cold and Arid Regions2012，4，3： | 3 |
| 11 | Estimation of the Land Surface Emissivity in the Hinterland of Taklimakan Desert显示文摘An accurate accounting of land surface emissivity(ε) is important both for the retrieval of surface temperatures and the calculation of the longwave surface energy budgets.Since ε is one of the important parameterizations in land surface models(LSMs),accurate accounting also improves the accuracy of surface temperatures and sensible heat fluxes simulated by LSMs.In order to obtain an accurate emissivity,this paper focuses on estimating ε from data collected in the hinterland of Taklimakan Desert by two different methods.In the first method,ε was derived from the surface broadband emissivity in the 8–14 μm thermal infrared atmospheric window,which was determined from spectral radiances observed by field measurements using a portable Fourier transform infrared spectrometer,the mean ε being 0.9051.The second method compared the observed and calculated heat fluxes under nearneutral atmospheric stability and estimated ε indirectly by minimizing the root-mean-square difference between them.The result of the second method found a mean value of 0.9042,which is consistent with the result by the first method.Although the two methods recover ε from different field experiments and data,the difference of meanvalues is 0.0009.The first method is superior to the indirect method,and is also more convenient. | LIU Yong-qiang Ali MAMTIMIN HUO Wen YANG Xing-hua LIU Xin-chun MENG Xian-yong HE Qing | 2014 | Journal of Mountain Science2014，11，6： | 3 |
| 12 | Observation of saltation activity at Tazhong area in Taklimakan Desert,China显示文摘A two-year field observation of saltation activity was carried out at Tazhong area,the hinterland area of the Taklimakan Desert with highly frequent dust storms.From 1 September 2008 to 31 August 2010,a piezoelectric saltation sensor(Sensit) was used to continuously collect the data on saltation activity at a level sand surface.Analysis on the data suggests that saltation activity can occur at any time of the year when conditions are favorable;however,the necessary conditions are rarely satisfied in most time.In the daytime of spring or summer,saltation activity can persist even over a continuous one-hour-or-so period.It is found that,from 1 September 2008 to 31 August 2010,saltation activity accounts for more than 3% of the total yearly time,and it tends to peak in spring and summer months with strong winds.During winter months when winds are weak,however,it is often at a minimum.It seems that precipitation does not appear to be significant in reducing saltation activity in arid regions like Tazhong. | Ali MAMTIMIN | 2013 | Journal of Arid Land2013，5，1： | 3 |
| 13 | Analysis on the temporal-spatial distribution character and effect factors of PM10 in the hinterland of Taklimakan Desert and surrounding area显示文摘In recent years, the physical and chemical properties of dust aerosols from the dust source area in northern China have attracted increased attention. In this paper, Thermo RP 1400a was used for online continuous observation and study of the hinterland of Taklimakan, Tazhong, and surrounding areas of Kumul and Hotan from 2004 to 2006. In combination with weather analysis during a sandstorm in the Tazhong area, basic characteristics and influencing factors of dust aerosol PM10 have been summarized as below: (1) The occurrence days of floating dust and blowing dust appeared with an increasing trend in Kumul, Tazhong and Hotan, while the number of dust storm days did not significantly change. The frequency and intensity of dust weather were major factors affecting the concentration of dust aerosol PM10 in the desert. (2) The mass concentration of PM10 had significant regional distribution characteristics, and the mass concentration at the eastern edge of Taklimakan, Kumul, was the lowest; second was the southern edge of the desert, Hotan; and the highest was in the hinterland of the desert, Tazhong. (3) High values of PM10 mass concentration in Kumul was from March to September each year; high values of PM10 mass concentration in Tazhong and Hotan were distributed from March to August and the average concentration changed from 500 to 1,000 μg/m3, respectively. (4) The average seasonal concentration changes of PM10 in Kumul, Tazhong and Hotan were: spring > summer > autumn > winter; the highest average concentration of PM10 in Tazhong, was about 1,000 μg/m3 in spring and between 400 and 900 μg/m3 in summer, and the average concentration was lower in autumn and winter, basically between 200 and 400 μg/m3. (5) PM10 concentration during the sandstorm season was just over two times the concentration of the non-sandstorm season in Kumul, Tazhong and Hotan. The average concentrations of sandstorm season in Tazhong were 6.2 and 3.6 times the average concentrations of non-sandstorm season in 2004 and 2008, respectively. (6) The mass concentration of PM10 had the following sequence during the dust weather: clear day < floating dust < floating and blowing dust < sandstorm. The wind speed directly affects the concentration of PM10 in the atmosphere, the higher the wind speed, the higher the mass concentration. Temperature, relative humidity and barometric pressure are important factors affecting the strength of storms, which could also indirectly affect the concentration change of PM10 in the atmosphere. | Ali Mamtimin | 2011 | Research in Cold and Arid Regions2011，3，6： | 1 |
| 14 | A field experiment on dust emission by wind erosion in the Taklimakan Desert 显示文摘 | Yang Xinghua He Qing All Mamtimin | 2012 | Acta Meteorologiea Siniea2012，26，2： | 1 |
| 15 | Air pollution and meteorological processes in the growing dryland city of Urumqi (Xin-jiang, China)显示文摘 | MAMTIMIN B MEIXNER F X | 2011 | Science of the Total Environment2011，409，： | 1 |
| 16 | Air pollution and meteorological processes in the growing dry land city of Urumqi(Xinjiang,China)显示文摘 | Mamtimin B Meixner F X | | 0，，： | 1 |
| 17 | Highly Sensitive and Selective Optical HCl Gas Sensor Based on Polymer Thin Film with Immobilized Congo Red显示文摘 | Mamtimin Mahmut Abliz Yimit Abdukadir Abudukayum Mariya Mamut and Kiminori Itoh | 2008 | Sensors Letters2008，6，2： | 1 |
| 18 | A Planar Optical Waveguide Sensor for Hydrogen Sulfide Detection显示文摘 | Abdukader Abdukayum Abliz Yimit Mamtimin Mahmut and Kiminori Itoh | 2007 | Sensors Letters2007，5，2： | 1 |
| 19 | The Strength Evaluation and eliability Analysis of Periodic Symmetric Struts Support显示文摘 | JINGAXIANG Yang YAXIN Zhang MAMTIMIN Geni | 2011 | Key Engineering Materials2011，，： | 1 |
| 20 | The characteristics of air pollution in the semi-arid city of Urumqi ( NW China) and its relation to climatological process 显示文摘 | Mamtimin B Meixner F X | 2007 | Geophysical Research Abstracts2007，9，06： | 1 |
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