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| 1 | Intraoperative blood loss in orthotopic liver transplantation:The predictive factors显示文摘Liver transplantation has been associated with massive blood loss and considerable transfusion requirements. Bleeding in orthotopic liver transplantation is multifactorial. Technical difficulties inherent to this complex surgical procedure and pre operative derangements of the primary and secondary coagulation system are thought to be the principal causes of perioperative hemorrhage. Intraoperative practices such as massive fluid resuscitation and resulting hypothermia and hypocalcemia secondary to citrate toxicity further aggravate the preexisting coagulopathy and worsen the perioperative bleeding. Excessive blood loss and transfusion during orthotopic liver transplant are correlated with diminished graft survival and increased septic episodes and prolonged ICU stay. With improvements in surgical skills, anesthetic technique, graft preservation, use of intraoperative cell savers and overall perioperative management, orthotopic liver transplant is now associated with decreased intra operative blood losses. The purpose of this review is to discuss the risk factors predictive of increased intra operative bleeding in patients undergoing orthotopic liver transplant. | Chandra Kant Pandey Anshuman Singh Kamal Kajal Mandeep Dhankhar Manish Tandon Vijay Kant Pandey Sunaina Tejpal Karna | 2015 | World Journal of Gastrointestinal Surgery2015，7，6： | 8 |
| 2 | 在有经历非肝的外科的肝疾病的病人的 Perioperative 风险因素显示文摘 The patients with liver disease present for various surgical interventions. Surgery may lead to complications in a significant proportion of these patients. These complications may result in considerable morbidity and mortality. Preoperative assessment can predict survival to some extent in patients with liver disease undergoing surgical procedures. A review of literature suggests nature and the type of surgery in these patients determines the peri-operative morbidity and mortality. Optimization of premorbid factors may help to reduce perioperative mortality and morbidity. The purpose of this review is to discuss the effect of liver disease on perioperative outcome; to understand various risk scoring systems and their prognostic significance; to delineate different preoperative variables implicated in postoperative complications and morbidity; to establish the effect of nature and type of surgery on postoperative outcome in patients with liver disease and to discuss optimal anaesthesia strategy in patients with liver disease. | Chandra Kant Pandey Sunaina Tejpal Karna Vijay Kant Pandey Manish Tandon Amit Singhal Vivek Mangla | 2012 | World Journal of Gastrointestinal Surgery2012，4，12： | 4 |
| 3 | 闪光对于减轻静脉置管痛的作用:一项前瞻性随机安慰剂对照研究显示文摘背景尽管静脉置管时的疼痛经常让人备受困扰,但通常都是在没有任何镇痛措施下进行静脉置管的。临床上曾尝试用一些药物和非药物方法来减轻静脉置管的疼痛,但结果各异。本研究拟评价一次闪光对于减轻静脉置管痛的效果。方法90例拟择期行腹腔镜胆囊切除术的ASAⅠ~Ⅱ级的成年患者(15~60岁),随机分为3组,每组30例,组1为对照组;组2为分散注意力组,即在非优势手的手背静脉进行置管前给患者照相而不使用闪光;组3为闪光组,静脉置管前照相并且使用闪光;在照相后立即使用18G的穿刺针进行静脉置管。结果每组均有2例患者首次静脉穿刺失败,在数据分析中即予以剔除,闪光组疼痛的发生率为50%(28例中14例发生),其他2组为100%(28例全部发生),通过视觉模拟评分评估的疼痛严重程度分散注意力组和闪光组显著低于对照组,而闪光组也显著低于分散注意力组。结论静脉置管前使用闪光是一种减轻疼痛的安全而简单有效的方法。 | Anil Agarwal GhanshvamYadav Devendra Gupta Manish Tandon Prabhat Kumar Singh Uttam Singh 吴志林(译) | 2009 | 麻醉与镇痛2009，，3： | 1 |
| 4 | Role of interstitial cells of Cajal in motility disorders of the bowel显示文摘 | Dhanpat Jain Khalid Moussa Manish Tandon Joan Culpepper-Morgan Deborah D Proctor | 2003 | The American Journal of Gastroenterology2003，，3： | 1 |
| 5 | Current State of Care for Diabetic Retinopathy in India显示文摘 | Kim Ramasamy Rajiv Raman Manish Tandon | 2013 | Current Diabetes Reports2013，，4： | 1 |
| 6 | Role of interstitial cells of Cajal in motility disorders of the bowel显示文摘 | Dhanpat Jain Khalid Moussa Manish Tandon Joan Culpepper-Morgan Deborah D Proctor | 2003 | The American Journal of Gastroenterology2003，，3： | 1 |
| 7 | Iridium(Ⅲ) catalyzed oxidation of toluene and ethyl benzene by cerium( 1V ) in acidic aqueous medium显示文摘 | Praveen K Tandon Manish S | 2009 | J Mol Catal A : Chemical2009，304，： | 1 |
| 8 | Tongue thickness in health vs cirrhosis of the liver:Prospective observational study显示文摘BACKGROUNDMalnutrition affects 40%-90% of patients with cirrhosis of the liver. L3 skeletalmuscle index (L3SMI) is presently accepted as the most objective and quantitativemeasure available for sarcopenia, a surrogate marker of malnutrition. L3SMIapplication is, however, limited by non-availability of computed tomographyscanning in remote areas, cost, need for extensive training, and the risk ofexposure to radiation. Therefore, an alternative dependable measure with wideravailability is needed. Malnutrition causes sarcopenia not only in skeletal musclesbut also in other muscular structures such as the psoas muscle, diaphragm andtongue. We therefore hypothesised that the tongue, being easily accessible forinspection and for measurement of thickness using ultrasonography, may be usedto document sarcopenia.AIMTo measure and compare tongue thickness in healthy individuals and in patientswith cirrhosis of the liver and to study its correlation with conventionalprognostic scores for patients with cirrhosis of the liver.METHODSTongue thickness was measured using ultrasonography. One hundred twentysubjects of either gender aged 18 to 65 years were studied, with 30 subjects in eachgroup. The tongue thickness was compared between groups based on “ChildTurcotte Pugh” (CTP) scores. The correlations between measured tonguethickness and “Model for end stage liver disease” (MELD) score and between age and measured tongue thickness were also assessed.RESULTSMean tongue thickness (mean ± SD) in patients with CTP class A, B and C was4.39 ± 0.39 cm, 4.19 ± 0.53 cm, and 3.87 ± 0.42, respectively, and was 4.33 ± 0.49 cmin normal healthy individuals. Significant differences were seen in tonguethickness between patients with CTP class C and those with CTP class A and B (P< 0.05). Patients with CTP class C also had a significantly reduced tonguethickness than normal individuals (P < 0.05). However, no significant differencewas seen in tongue thickness between patients with CTP class A and B andnormal individuals. A statistically significant, negative correlation was foundbetween MELD score and tongue thickness (r = -0.331) (P < 0.001). No correlationwas observed between L3SMI and MELD score (r = 0.074, P = 0.424). L3SMI(mean ± SD) in healthy subjects was 39.66 ± 6.8 and was 38.26 ± 8.88 in patientswith CTP class C, and the difference was not significant. No significant correlationwas found between age of the patients and tongue thickness. Intra-classcorrelation coefficient was used to determine the reliability of the tonguethickness measurements. The intra-class correlation coefficient was 0.984 (95%CI:0.979-0.989) and was indicative of good reliability.CONCLUSIONTongue thickness measured by ultrasonography, correlates significantly with theseverity of liver disease, as assessed by CTP and MELD scores. The patients with aCTP score ≥ 10 have significantly reduced tongue thickness as compared tonormal individuals and those with less severe liver disease and CTP scores of 5-9.No significant difference in tongue thickness was found between healthyindividuals and CTP class A and B patients. | Manish Tandon Harshita Singh Nishant Singla Priyanka Jain Chandra Kant Pandey | 2020 | World Journal of Gastrointestinal Pharmacology and Therapeutics2020，11，3： | 0 |
| 9 | Diagnostic and therapeutic challenge of heart failure after liver transplant:Case series显示文摘Heart failure(HF) following liver transplant(LT) surgery is a distinct clinical entity with high mortality. It is known to occur in absence of obvious risk factors. No preoperative workup including electrocardiogram, echocardiography at rest and on stress, reasonably prognosticates the risk. In patients of chronic liver disease, cirrhotic cardiomyopathy, alcoholic cardiomyopathy, and stress induced cardiomyopathy have each been implicated as a cause for HF after LT. However distinguishing one etiology from another not only is difficult, several etiologies may possibly coexist in a given patient. Diagnostic dilemma is further compounded by the fact that presentation and management of HF irrespective of the possible underlying cause, remains the same. In this case series, 6 cases are presented and in the light of existing literature modification in the preoperative workup are suggested. | Manish Tandon Sunaina Tejpal Karna Chandra Kant Pandey Ravindra Chaturvedi | 2017 | World Journal of Hepatology2017，9，33： | 0 |
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