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318篇 您的检索式:作者名="Manley M"
    题名 作者 年代 出处 被引量
1非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 1998英国医学杂志中文版1998,0,3:11
2Aquaporin-4 detection in mice reduces brain edema after acute water intoxication and ischemic stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,:2
3Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and iachemic stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
4Aquaporin-4 deletion in mice reduces brain edema after acute water toxication and ischemic stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
5Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke 显示文摘 Fujimura M Ma T 2000Nat Med2000,6,1:1
6New experience with alumi- na - on - alumina ceramic bearing for total hip arthroplasty 显示文摘D' Antonio J Capello W Manley M 2002J Arthroplasty2002,17,:1
7Greatly impaired migration of implanted aquapor in-4-deficient astroglial cells in mouse brain toward a site of in jury显示文摘Auguste K I Jin S Uchida K Yan D Manley G T Papadopou los M C etal 2007FASEB J2007,21,:1
8Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemia stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
9Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,:1
10Early amidation approach to 3- -2-indolinones 显示文摘Manley JM Kalman M J Conway BG 2003J Org Chem2003,68,16:1
11Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
12Aquaporin 4 deletion in mice reduces brain edema after acute water intoxi- cation and isehemic stroke 显示文摘MANLEY G T FUJIMURA M MA T 2000Nat Med2000,6,2:1
13Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
14Key influences on construction innovation显示文摘BLAYSE A M MANLEY K 2004Construction Innovation:Information Process Management2004,4,3:1
15Near-infrared spectroscopy and hyperspectral imaging:non-destructive analysis of biological materials显示文摘Manley M 2014Chemical Society Reviews2014,43,:1
16Vapor-liquid equilibrium data for the NH3-H2O system and its description with a modified cubic equation of state显示文摘Smolen T M Manley D B Poling B E 1991J Chem Eng Data1991,36,2:1
17Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain显示文摘Zador Z Magzoub M Jin S Manley G T Papadopoulos M C Verkman A S 2008FASEB J2008,22,:1
18Clinical intervention in tobacco control显示文摘Manley M Epps RP Husten C 1991JAMA1991,266,22:1
19Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke 显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
20Aquaporin4 deletion in mice reduces brain edema after acute water intoxication and ischemie stroke 显示文摘Manley GT Fujimura M Ma T 2000Nat Med2000,6,2:1
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