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| 1 | Spatial patterns of vegetation and climate in the North China Plain during the Last Glacial Maximum and Holocene climatic optimum显示文摘Reconstructing the spatial patterns of regional climate and vegetation during specific intervals in the past is important for assessing the possible responses of the ecological environment under future global warming scenarios. In this study, we reconstructed the history of regional vegetation and climate based on six radiocarbon-dated pollen records from the North China Plain. Combining the results with existing pollen records, we reconstruct the paleoenvironment of the North China Plain during the Last Glacial Maximum(LGM) and the Holocene Climatic Optimum(HCO). The results show that changes in the regional vegetation since the LGM were primarily determined by climatic conditions, the geomorphic landscape and by human activity.During the LGM, the climate was cold and dry;mixed broadleaf-coniferous forest and deciduous-evergreen broadleaf forest developed in the southern mountains, and cold-resistant coniferous forest and mixed broadleaf-coniferous forest were present in the northern mountains. The forest cover was relatively low, with mesophytic and hygrophilous meadow occupying the southern part of the plain, and temperate grassland and desert steppe were distributed in the north;Chenopodiaceae-dominated halophytes grew on the exposed continental shelf of the Bohai Sea and Yellow Sea. During the HCO, the climate was warm and wet;deciduous broadleaf forest and deciduous-evergreen broadleaf forest, with subtropical species, developed in the southern mountains, and deciduous broadleaf forest with thermophilic species was present in northern mountains. Although the degree of forest cover was greater than during the LGM, the vegetation of the plain area was still dominated by herbs, while halophytes had migrated inland due to sea level rise. In addition, the expansion of human activities, especially the intensification of cultivation,had a significant influence on the natural vegetation. Our results provide data and a scientific basis for paleoclimate modelling and regional carbon cycle assessment in north China, with implications for predicting changes in the ecological environment under future global warming scenarios. | Manyue LI Shengrui ZHANG Qinghai XU Jule XIAO Ruilin WEN | 2019 | Science China Earth Sciences2019，62，8： | 4 |
| 2 | Cytosolic phospholipase A2α modulates cell-matrix adhesion via the FAK/paxillin pathway in hepatocellular carcinoma显示文摘Objective: To explore the effect of cytosolic phospholipase A2α(cPLA2α) on hepatocellular carcinoma(HCC) cell adhesion and the underlying mechanisms.Methods: Cell adhesion, detachment, and hanging-drop assays were utilized to examine the effect of cPLA2α on the cell-matrix and cell-cell adhesion. Downstream substrates and effectors of cPLA2α were screened via a phospho-antibody microarray.Associated signaling pathways were identified by the functional annotation tool DAVID. Candidate proteins were verified using Western blot and colocalization was investigated via immunofluorescence. Western blot and immunohistochemistry were used to detect protein expression in HCC tissues. Prognosis evaluation was conducted using Kaplan-Meier and Cox-proportional hazards regression analyses.Results: Our findings showed that cPLA2α knockdown decreases cell-matrix adhesion but increases cell-cell adhesion in HepG2 cells. Microarray analysis revealed that phosphorylation of multiple proteins at specific sites were regulated by cPLA2α. These phosphorylated proteins were involved in various biological processes. In addition, our results indicated that the focal adhesion pathway was highly enriched in the cPLA2α-relevant signaling pathway. Furthermore, cPLA2α was found to elevate phosphorylation levels of FAK and paxillin, two crucial components of focal adhesion. Moreover, localization of p-FAK to focal adhesions in the plasma membrane was significantly reduced with the downregulation of cPLA2α. Clinically, cPLA2α expression was positively correlated with p-FAK levels. Additionally, high expression of both cPLA2α and p-FAK predicted the worst prognoses for HCC patients.Conclusions: Our study indicated that cPLA2α may promote cell-matrix adhesion via the FAK/paxillin pathway, which partly explains the malignant cPLA2α phenotype seen in HCC. | Piao Guo Yuchao He Lu Chen Lisha Qi Dongming Liu Ziye Chen Manyu Xiao Liwei Chen Yi Luo Ning Zhang Hua Guo | 2019 | Cancer Biology & Medicine2019，16，2： | 2 |
| 3 | A parallel algorithm based on Galerkin theory block-tridiagonal liner systems显示文摘 | Lv Quanyi Xiao Manyu Zhou Min | 2007 | Applied Mathematics and Computation2007，187，： | 1 |
| 4 | A parallel iterative method for solving periodical block-tridiagonal linear equations显示文摘 | Xiao Manyu Lu Quanyi | 2007 | Applied Mathematics and Computation2007，184，： | 1 |
| 5 | A parallel algorithm based on Galerkin theory for block-tridiagonal linear systems显示文摘 | Lu Quanyi Xiao Manyu Zhou Min | 2007 | Applied Mathematics and Computation2007，187，： | 1 |
| 6 | A parallel algorithm based on Galerkin theory for block-tridiagonal linear sys- tems显示文摘 | LV Quanyi XIAO Manyu ZHOU Min | 2007 | Applied Mathematics and Computation2007，187，： | 1 |
| 7 | A parallel algorithm based on Galerkin theory for block-tridiagonal linear systems显示文摘 | LU Quanyi XIAO Manyu ZHOU Min | 2007 | Applied Mathematics and Computation2007，187，： | 1 |
| 8 | A parallel algorithm based on Galerkin theory for block-tridiagonal linear systems显示文摘 | Lv Quanyi Xiao Manyu Zhou Min | 2007 | Applied Mathematics and Communication2007，187，2： | 1 |
| 9 | A Gaussian process regression‐based surrogate model of the varying workpiece dynamics for chatter prediction in milling of thin‐walled structures显示文摘Since the dynamics of thin‐walled structures instantaneously varies during the milling process,accurate and efficient prediction of the in‐process workpiece(IPW)dynamics is critical for the prediction of chatter stability of milling of thin‐walled structures.This article presents a surrogate model of the IPW dynamics of thin‐walled structures by combining Gaussian process regression(GPR)with proper orthogonal decomposition(POD)when IPW dynamics at a large number of cutting positions has to be predicted.The GPR method is used to learn the mapping between a set of the known IPW dynamics and the corresponding cutting positions.POD is used to reduce the order of the matrix assembled by the mode shape vectors at different cutting positions,before the GPR model of the IPW mode shape is established.The computation time of the proposed model is mainly composed of the time taken for predicting a known set of IPW dynamics and the time taken for training GPR models.Simulation shows that the proposed model requires less computation time.Moreover,the accuracy of the proposed model is comparable to that of the existing methods.Comparison between the predicted stability lobe diagram and the experimental results shows that IPW dynamics predicted by the proposed model is accurate enough for predicting the stability of milling of thin‐walled structures. | Yun Yang Yang Yang Manyu Xiao Min Wan Weihong Zhang | 2022 | International Journal of Mechanical System Dynamics2022，2，1： | 0 |
| 10 | Spatial and Temporal Change of Habitat Quality of Poyang Lake Basin in China at Small Watershed Scale and Its Multidimensional Response to Landscape Pattern显示文摘The health and function of ecosystems are largely determined by the quality of habitat,and the optimal regulation of landscape patterns has become an important way to improve regional habitat quality.This article takes the Poyang Lake Basin of China as a case,reveals the spatial and temporal change of its habitat quality at the small watershed scale,and attempts to examine the multidimensional response of habitat quality to landscape pattern changes with respect to landscape compositions and landscape configuration.The results show:1)from 2000 to 2020,the overall landscape fragmentation of the basin decreased,the landscape aggregation in the central small watersheds changed significantly,and the spatial distribution of landscape elements in the central and southern small watersheds were relatively homogeneous.2)The overall habitat quality of the Poyang Lake Basin is at a middle to high level,with significant spatial differentiation,showing the distribution characteristics of‘high in the periphery,low in the center,high in the south and low in the north’.3)Both landscape compositions and landscape configurations influenced habitat quality,but there were obvious differences in the response degree.From the landscape composition and configuration dimension,the influence of landscape composition on habitat quality was greater than that of landscape configuration;from the multilevel landscape configuration dimension,compared to landscape level,landscape configuration at the class level impacted habitat quality more deeply.To the end,this article proposes a differentiated regulation strategy for habitat quality conservation in small watersheds from the perspective of landscape patterns to improve the ecological service level of Poyang Lake Basin. | BI Manyu ZHONG Yexi XIAO Zeping FENG Xinghua MA Hongzhi | 2023 | Chinese Geographical Science2023，33，3： | 0 |
| 11 | Scalable Core–Sheath Yarn for Boosting Solar Interfacial Desalination Through Engineering Controllable Water Supply显示文摘Tailoring water supply to achieve confined heating has proven to be an effective strategy for boosting solar interfacial evaporation rates.However,because of salt clogging during desalination,a critical point of constriction occurs when controlling the water rate for confined heating.In this study,we demonstrate a facile and scalable weaving technique for fabricating core-sheath photothermal yarns that facilitate controlled water supply for stable and efficient interracial solar desalination.The core-sheath yarn comprises modal fibers as the core and carbon fibers as the sheaths.Because of the core-sheath design,remarkable liquid pumping can be enabled in the carbon fiber bundle of the dispersed superhydrophilic modal fibers.Our woven fabrics absorb a high proportion(92%)of the electromagnetic radiation in the solar spectrum because of the weaving structure and the carbon fiber sheath.Under one-sun(1 kW·m^(-2))illumination,our woven fabric device can achieve the highest evaporation rate(of 2.12kg·m^(-2)·h^(-1) with energy conversion efficiency:93.7%)by regulating the number of core-sheath yarns.Practical application tests demonstrate that our device can maintain high and stable desalination performance in a 5 wt%NaCl solution. | Xingfang Xiao Luqi Pan Tao Chen Manyu Wang Lipei Ren Bei Chen Yingao Wang Qian Zhang Weilin Xu | 2023 | Engineering2023，，11： | 0 |
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