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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Longevity of optically activated, high gain gaas photoconductive semiconductor switches 显示文摘 | LOUBRIEL G ZUTAVERN F MAR A | 1998 | IEEE transactions on Plasma science1998，26，5： | 1 |
| 3 | Genetic variability related to serum uric acid concentration and risk of Parkinson’s disease显示文摘 | Isabel González‐Aramburu Pascual Sánchez‐Juan Silvia Jesús Ana Gorostidi Eduardo Fernández‐Juan Fátima Carrillo María Sierra Pilar Gómez‐Garre María T. Cáceres‐Redondo José Berciano Javier Ruiz‐Martínez Onofre Combarros Pablo Mir Jon Infante | 2013 | Mov Disord2013，，： | 1 |
| 4 | Crystal structure and DNA interaction of the facial-type rac-tris[2-(aminomethyl) benzimidazole] cobalt(Ⅲ) complex显示文摘 | JORDI G S MARíA J P MERCèF B | | 0，，25： | 1 |
| 5 | Sandoval genetic algorithms for optimal placement of phasor measurement units in electrical networks显示文摘 | Marín F J García-Lagos F Joya G | 2003 | Electronics Letters2003，39，19： | 1 |
| 6 | 查看详情显示文摘 | María L G P Patricia P B Roberto R G José L M V Antonia G F | | 0，，27： | 1 |
| 7 | Rejection after conversion to a proliferation signal inhibitor in chronic heart transplantation显示文摘 | Francisco González‐Vílchez José A. Vázquez de Prada María J. Paniagua Luis Almenar Sonia Mirabet Manuel Gómez‐Bueno Beatriz Díaz‐Molina Jose M. Arizón Juan Delgado Félix Pérez‐Villa María G. Crespo‐Leiro Luis Martínez‐Dolz Eulalia Roig Javier Segovia José | 2013 | Clin Transplant2013，，6： | 1 |
| 8 | Doped contacts for high longevity optically activated, high-gain GaAs photoconductive semiconductor switehes显示文摘 | Mar A Loubriel G M Zutavern F J | 2000 | IEEE Transactions on Plasma Science2000，28，5： | 1 |
| 9 | Performance of deep phase modulation interferometry显示文摘 | F Guzmán Cervantes G Heinzel A F García Marín | 2010 | Opt Express2010，，4： | 1 |
| 10 | Stopped flow kinetic-spectrophotometric determination of Diquat in waters显示文摘 | Teresa G D Isabel D M María F | 2002 | Water Research2002，36，3： | 1 |
| 11 | Longevity of optically activated, high gain GaAs photoconductive semiconductor switches 显示文摘 | Loubriel G M Zutavern F J Alan Mar et al | 1998 | IEEE Transactions on Plasma Science1998，26，5： | 1 |
| 12 | Longevity of optically activated high gain GaAs photoconductive semiconductor switches显示文摘 | Loubriel G Zutavern F Mar A | 1998 | IEEE Transactions on Plasma Science1998，26，5： | 1 |
| 13 | Synthesis gas generation by chemical-looping reforming using a Ni based oxygen carrier显示文摘 | LUIS F D MARíA O FRANCISCO G L JUAN A ALBERTO A PILAR G | 2009 | Energy Procedia2009，1，1： | 1 |
| 14 | Synthesis gas generation by chemical-looping reforming in a batch fluidized bed reactor using Ni-based oxygen carriers显示文摘 | LUIS F D MARíA O FRANCISCO G L JUAN A ALBERTO A PILAR G | 2008 | Chem Eng J2008，144，2： | 1 |
| 15 | Temperature and particle-size dependent viscosity data for water-based nanofluids-hysteresis phenomenon显示文摘 | Nguyen C T Desgranges F Roy G Galanis N Maré T Boucher S Angue Mintsa H | | 0，，06： | 1 |
| 16 | Effects of plasma surface treatments of diamond-like carbon and polymeric substrata on the cellular behavior of human fibroblasts显示文摘 | Carmen L S Mar F G Francisco Y | 2013 | J Biol Appl2013，27，2： | 1 |
| 17 | Hydrogen production with CO2 capture by coupling steam reforming of methane and chemical-looping combustion: Use of an iron-based waste product as oxygen carrier burning a PSA tail gas显示文摘 | MARíA O PILAR G LUIS F D FRANCISCO G L ALBERTO A | 2011 | J Power Sources2011，196，9： | 1 |
| 18 | Surface area of compressed expanded graphite显示文摘 | Celzard A MarêchéJ F Furdin G | 2002 | Carbon2002，40，14： | 1 |
| 19 | A low computational-cost method to fuse IKONOS images using the spectral response function of its sensors显示文摘 | María G Xavier O Octavi F | 2006 | IEEE Transaction on Geoscience and Remote Sensing2006，44，6： | 1 |
| 20 | Serological ev- idence of an early seroconversion to Simian virus 40 in healthy children and adolescents显示文摘 | Taronna A Mazzoni E Corallini A Bononi I Pietro bon S Guerra G Palmonari C Borgna Pignatti C Co mar M Bovenzi M Casali F Marci R Rezza G Barbanti-Brodano G Tognon M Martini F | 2013 | PLoS One2013，8，61： | 1 |
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