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| 1 | Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses:A multicenter study显示文摘AIM:To evaluate the ability of endoscopic ultrasound(EUS) elastography to distinguish benign from malignant pancreatic masses and lymph nodes.METHODS:A multicenter study was conducted and included 222 patients who underwent EUS examination with assessment of a pancreatic mass(n=121) or lymph node(n=101).The classification as benign or malignant,based on the real time elastography pattern,was compared with the classif ication based on the B-mode EUS images and with the fi nal diagnosis obtained by EUS-guided fi ne needle aspiration(EUS-FNA) and/or by surgical pathology.An interobserver study was performed.RESULTS:The sensitivity and specificity of EUS elastography to differentiate benign from malignant pancreatic lesions are 92.3% and 80.0%,respectively,compared to 92.3% and 68.9%,respectively,for the conventional B-mode images.The sensitivity and specificity of EUS elastography to differentiate benign from malignant lymph nodes was 91.8% and 82.5%,respectively,compared to 78.6% and 50.0%,respectively,for the B-mode images.The kappa coefficient was 0.785 for the pancreatic masses and 0.657 for the lymph nodes.CONCLUSION:EUS elastography is superior compared to conventional B-mode imaging and appears to be able to distinguish benign from malignant pancreatic masses and lymph nodes with a high sensitivity,specificity and accuracy.It might be reserved as a second line examination to help characterise pancreatic masses after negative EUS-FNA and might increase the yield of EUS-FNA for lymph nodes. | Marc Giovannini Botelberge Thomas Bories Erwan Pesenti Christian Caillol Fabrice Esterni Benjamin Monges Geneviève Arcidiacono Paolo Deprez Pierre Yeung Robert Schimdt Walter Schrader Hanz Szymanski Carl Dietrich Christoph Eisendrath Pierre Van Laethem Jean-Luc Devière Jacques Vilmann Peter Saftoiu Andrian | 2009 | World Journal of Gastroenterology2009，15，13： | 48 |
| 2 | Usefulness of staging systems and prognostic scores for hepatocellular carcinoma treatments显示文摘Therapeutic management of hepatocellular carcinoma(HCC) is quite complex owing to the underlying cirrhosis and portal vein hypertension. Different scores or classification systems based on liver function and tumoral stages have been published in the recent years. If none of them is currently 'universally' recognized, the Barcelona Clinic Liver Cancer(BCLC) staging system has become the reference classification system in Western countries. Based on a robust treatment algorithm associated with stage stratification, it relies on a high level of evidence. However, BCLC stage B and C HCC include a broad spectrum of tumors but are only matched with a single therapeutic option. Some experts have thus suggested to extend the indications for surgery or for transarterial chemoembolization. In clinical practice, many patients are already treated beyond the scope of recommendations. Additional alternative prognostic scores that could be applied to any therapeutic modality have been recently proposed. They could represent complementary tools to the BCLC staging system and improve the stratification of HCC patients enrolled in clinical trials, as illustrated by the NIACE score. Prospective studies are needed to compare these scores and refine their role in the decision making process. | Xavier Adhoute Guillaume Penaranda Jean Luc Raoul Patrice Le Treut Emilie Bollon Jean Hardwigsen Paul Castellani Hervé Perrier Marc Bourlière | 2016 | World Journal of Hepatology2016，8，17： | 7 |
| 3 | Hepatitis B virus genotypes and extrahepatic manifestations显示文摘 | Patrice Cacoub David Saadoun Marc Bourlière Hacene Khiri Agnes Martineau Yves Benhamou Marina Varastet Stanislas Pol Vincent Thibault Michel Rotily Philippe Halfon | 2005 | Journal of Hepatology2005，，5： | 5 |
| 4 | Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) – NCT01514890<!-- Doctopic: VH -->显示文摘 | Christophe Hézode Hélène Fontaine Céline Dorival Dominique Larrey Fabien Zoulim Valérie Canva Victor de Ledinghen Thierry Poynard Didier Samuel Marc Bourlière Jean-Pierre Zarski Jean-Jacques Raabe Laurent Alric Patrick Marcellin Ghassan Riachi Pierre-Henr | 2013 | Journal of Hepatology2013，，： | 2 |
| 5 | Ultrasound diagnosis of occult pneumothorax显示文摘 | Daniel A. Lichtenstein Gilbert Mezière Nathalie Lascols Philippe Biderman Jean-Paul Courret Agnès Gepner Ivan Goldstein Marc Tenoudji-Cohen | 2005 | Critical Care Medicine2005，，： | 1 |
| 6 | EUS-guided pancreatogastrostomy and pancreatobulbostomy for the treatment of pain in patients with pancreatic ductal dilatation inaccessible for transpapillary endoscopic therapy显示文摘 | Geneviève Tessier Erwan Bories Marianna Arvanitakis Axel Hittelet Christian Pesenti Olivier Le Moine Marc Giovannini Jacques Devière | 2007 | Gastrointestinal Endoscopy2007，，2： | 1 |
| 7 | Neural remodeling in retinal degeneration显示文摘 | Marc RE Jones BW Watt CB | 2003 | Prog Retin Eye Res2003，22，5： | 1 |
| 8 | Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial显示文摘 | Peter Malfertheiner Franco Bazzoli Jean-Charles Delchier Krysztof Celi?ski Monique Giguère Marc Rivière Francis Mégraud | 2011 | The Lancet2011，，9769： | 1 |
| 9 | Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) – NCT01514890<!-- Doctopic: VH -->显示文摘 | Christophe Hézode Hélène Fontaine Céline Dorival Dominique Larrey Fabien Zoulim Valérie Canva Victor de Ledinghen Thierry Poynard Didier Samuel Marc Bourlière Jean-Pierre Zarski Jean-Jacques Raabe Laurent Alric Patrick Marcellin Ghassan Riachi Pierre-Henr | 2013 | Journal of Hepatology2013，，： | 1 |
| 10 | Neural remodeling inretinal degen- eration显示文摘 | Marc RE Jones BW Watt CB | 2003 | Prog Retin Eye Res2003，22，5： | 1 |
| 11 | Protease inhibitor‐based triple therapy in chronic hepatitis C: guidelines by the French Association for the Study of the Liver显示文摘 | Vincent Leroy Lawrence Serfaty Marc Bourlière Jean‐Pierre Bronowicki Patrick Delasalle Alexandre Pariente Stanislas Pol Fabien Zoulim Georges‐Philippe Pageaux | 2012 | Liver Int2012，，10： | 1 |
| 12 | The chromatic organization of the goldfishcone mosaic显示文摘 | Marc RE Sperling HG | 1976 | Vision Rea1976，16，11： | 1 |
| 13 | Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration 显示文摘 | Marc RE Jones BW Watt CB Vazquez-Chona F Vaughan DK Organisciak DK | 2008 | Mol Vision2008，25，14： | 1 |
| 14 | Relationships between endosonographic appearance and clinical or manometric features in patients with achalasia显示文摘 | Marc Barthet Pierre Mambrini Patrick Audibert Christian Boustière Thierry Helbert Jean-Guy Bertolino Jacques Peyrot Jacques Salducci Jean-Charles Grimaud | 1998 | European Journal of Gastroenterology & Hepatology1998，，7： | 1 |
| 15 | Extreme retinal remodeling triggered by light damage:implications for age related macular degeneration显示文摘 | MARC RE JONES BW WATT CB | | 0，，93： | 1 |
| 16 | Neural remodeling in retinal degeneration 显示文摘 | Marc RE Ones BW Watt CB | 2003 | Prog Retin Eye Res2003，22，5： | 1 |
| 17 | Extreme retinal remodeling triggered by light damage : implications for age related maeular de- generation 显示文摘 | Marc RE Jones BW Watt CB | 2008 | Mol Vis2008，14，： | 1 |
| 18 | Neural remodeling in retinal degeneration显示文摘 | Marc RE Jones BW Watt CB | 2003 | Prog Retin Eye Res2003，22，： | 1 |
| 19 | Recent Developments in Myofibroblast Biology显示文摘 | Boris Hinz Sem H. Phan Victor J. Thannickal Marco Prunotto Alexis Desmoulière John Varga Olivier De Wever Marc Mareel Giulio Gabbiani | 2012 | The American Journal of Pathology2012，，4： | 1 |
| 20 | A multicenter randomized phase II study of sequential epirubicin/cyclophosphamide followed by docetaxel with or without celecoxib or trastuzumab according to HER2 status, as primary chemotherapy for localized invasive breast cancer patients显示文摘 | Jean-Yves Pierga Suzette Delaloge Marc Espié Etienne Brain Brigitte Sigal-Zafrani Marie-Christine Mathieu Philippe Bertheau Jean Marc Guinebretière Marc Spielmann Alexia Savignoni Michel Marty | 2010 | Breast Cancer Research and Treatment2010，，2： | 1 |
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