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| 1 | Acute effects of physical exercise in type 2 diabetes: A review显示文摘The literature has shown the efficiency of exercise in the control of type 2 diabetes(T2D), being suggested as one of the best kinds of non-pharmacological treatments for its population. Thus, the scientific production related to this phenomenon has growing exponentially. However, despite its advances, still there is a lack of studies that have carried out a review on the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in individuals with T2 D, not to mention that in a related way, these themes have been very little studied today. Therefore, the aim of this study was to organize and analyze the current scientific production about the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in T2 D individuals. For such, a research with the following keywords was performed:-exercise; diabetes and post-exercise hypotension; diabetes and excess post-exercise oxygen consumption; diabetes and acute effects in PUBMED, SCIELO and HIGHWIRE databases. From the analyzed studies, it is possible to conclude that, a single exercise session can promote an increase in the bioavailability of nitric oxide and elicit decreases in postexercise blood pressure. Furthermore, the metabolic stress from physical exercise can increase the oxidation of carbohydrate during the exercise and keep it, in high levels, the post exercise consumption of O2, this phenomenon increases the rate of fat oxidation during recovery periods after exercise, improves glucose tolerance and insulin sensitivity and reduces glycemia between 2-72 h, which seems to be dependent on the exercise intensity and duration of the effort. | Ricardo Yukio Asano Marcelo Magalhes Sales Rodrigo Alberto Vieira Browne José Fernando Vila Nova Moraes Hélio José Coelho Júnior Milton Rocha Moraes Hebert Gustavo Simoes | 2014 | World Journal of Diabetes2014，5，5： | 8 |
| 2 | Chronic stress sensitizes rats to pancreatitis induced by cerulein:Role of TNF-α显示文摘AIM:To investigate chronic stress as a susceptibility factor for developing pancreatitis,as well as tumor necrosis factor-α (TNF-α) as a putative sensitizer.METHODS:Rat pancreatic acini were used to analyze the influence of TNF-α on submaximal (50 pmol/L) cholecystokinin (CCK) stimulation.Chronic restraint (4 h every day for 21 d) was used to evaluate the effects of submaximal (0.2 μg/kg per hour) cerulein stimulation on chronically stressed rats.RESULTS:In vitro exposure of pancreatic acini toTNF-α disorganized the actin cytoskeleton.This was further increased by TNF-α/CCK treatment,which additionally reduced amylase secretion,and increased trypsin and nuclear factor-κB activities in a protein-kinase-C δ and ε-dependent manner.TNF-α/CCK also enhanced caspases' activity and lactate dehydrogenase release,induced ATP loss,and augmented the ADP/ATP ratio.In vivo,rats under chronic restraint exhibited elevated serum and pancreatic TNF-α levels.Serum,pancreatic,and lung inflammatory parameters,as well as caspases' activity in pancreatic and lung tissue,were substantially enhanced in stressed/cerulein-treated rats,which also experienced tissues' ATP loss and greater ADP/ATP ratios.Histological examination revealed that stressed/cerulein-treated animals developed abundant pancreatic and lung edema,hemorrhage and leukocyte infiltrate,and pancreatic necrosis.Pancreatitis severity was greatly decreased by treating animals with an anti-TNF-αantibody,which diminished all inflammatory parameters,histopathological scores,and apoptotic/necrotic markers in stressed/cerulein-treated rats.CONCLUSION:In rats,chronic stress increases susceptibility for developing pancreatitis,which involves TNF-α sensitization of pancreatic acinar cells to undergo injury by physiological cerulein stimulation. | Marcelo G Binker Andres A Binker-Cosen Daniel Richards Herbert Y Gaisano Rodica H de Cosen Laura I Cosen-Binker | 2010 | World Journal of Gastroenterology2010，16，44： | 7 |
| 3 | Effects of salinity on Brazilian flounder Paralichthys orbignyanus from fertilization to juvenile settlement 显示文摘 | Lufs A S Luciano S F Marcelo H O | 2007 | Aquaculture2007，262，24： | 1 |
| 4 | Raman spectroscopic investigation of maghemite ferrofluids modified by the adsorption of zinc tetrasulfonated phthalocyanine显示文摘 | Jean C O Silva Marcelo H Sousa Francisco A Tourinho | 2002 | Langmuir2002，18，14： | 1 |
| 5 | Stabilizing controller design for uncertain nonlinear system using fuzzy models显示文摘 | Marcelo C M Teixeira Stanislaw H Zak | 1999 | IEEE Trans on Fuzzy System1999，7，2： | 1 |
| 6 | Characterization of the Peri-Infarct Zone by Contrast-Enhanced Cardiac Magnetic Resonance Imaging Is a Powerful Predictor of Post–Myocardial Infarction Mortality显示文摘 | Andrew T. Yan Adolphe J. Shayne Kenneth A. Brown Sandeep N. Gupta Carmen W. Chan Tuan M. Luu Marcelo F. Di Carli H Glenn Reynolds William G. Stevenson Raymond Y. Kwong | 2006 | Circulation2006，，1： | 1 |
| 7 | Stabilizing Controller Design for Uncertain Nonlinear Systems Using Fuzzy Models 显示文摘 | Marcelo C M Teixeira Stanislaw H Zak | 1999 | IEEE TRANSACTIONS ON FUZZY SYSTEMS (S1063~6706)1999，7，2： | 1 |
| 8 | Development and characterization of a tissue-engineered human oral mucosa equivalent produced in a serum-free culture system 显示文摘 | Izumi K Tefashi H Marcelo CL | 2000 | J Dent Res2000，79，3： | 1 |
| 9 | Stabilizing controller design for uncertain nonlinear systems using fuzzy models 显示文摘 | MARCELO C M TEIXEIRA STANISLAW H ZAK | 1999 | IEEE Trans Fuzzy Systems1999，7，2： | 1 |
| 10 | Time resolved fluorescence spectroscopy of quercetin and morin complexes with Al3+显示文摘 | Amanda C Gutierrez Marcelo H | 2002 | Spectrochimica Acta Part A2002，58，： | 1 |
| 11 | Role of hormonal levelson hospital mortality for male patients with severe traumaticbrain injury显示文摘 | Alexandre H Marcelo F Rodrigo D | 2014 | Brain Inj2014，28，10： | 1 |
| 12 | Part-whole dissemination of large multimedia contents in opportunistic networks显示文摘 | Nadjet B Marcelo D Luís H M | 2012 | Computer Communications2012，35，： | 1 |
| 13 | Development and characterization of a tissue-engineered human oral mucosa equivalent produced in a serum-free culture system显示文摘 | Izumi K Terashi H Marcelo CL | 2000 | J Dent Res2000，79，3： | 1 |
| 14 | Animal response to drastic changes in oxygen availability and physiological oxidative stress显示文摘 | Marcelo H L Tania Z S | 2002 | Comparative Biochemistry and Physiology Part C2002，133，： | 1 |
| 15 | Singularity robust algorithm in serial manipulators显示文摘 | Oetomo Denny Marcelo H | 2009 | Robotics and Computer-Integrate Manufacturing2009，25，1： | 1 |
| 16 | Current knowledge and management of vascular anomalies显示文摘 | Marcelo H Denise MA Travis DR | | 0，，03： | 1 |
| 17 | Time-resolved fluorescence spectroscopy of cationic dyes incor- porated in silica matrix by high pressure compaction 显示文摘 | Marcelo H Gehlen Robson V Pereira Marcia R Gallas | 2006 | Jour- nal of Photochemistry and Photobiology A: Chemistry2006，181，： | 1 |
| 18 | Peroxisome proliferator-activated receptor-γ ligand,15-deoxy-△12,14-prostaglandin J2,reduces neutrophil migration via a nitric oxide pathway显示文摘 | Marcelo H Napimoga Silvio M Vieira | 2008 | J Immunol2008，180，： | 1 |
| 19 | Membrane changes during different stages of a freeze–thaw protocol for equine semen cryopreservation显示文摘 | Deborah M Neild Bart M Gadella Mar??a Graciela Chaves Marcelo H Miragaya Ben Colenbrander Alicia Agüero | 2002 | Theriogenology2002，，8： | 1 |
| 20 | Hyperbranched Polyamines for Transfection显示文摘 | Wiebke F Marcelo C Rainer H | 2010 | Top Curr Chem2010，296，： | 1 |
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