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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Exprimental campaigns on textile wastewater for reuse by means of different membrane processes显示文摘 | MARCUCCI M CIARDELLI G MATTEUCCI A | 2002 | Desalination2002，149，123： | 1 |
| 3 | Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity显示文摘 | Laurent D Marcucci M | 1999 | J Clin Invest1999，103，： | 1 |
| 4 | Propolis:chemical composition biological properties and the rapeutical activity显示文摘 | M C Marcucci | 1995 | Apidologie1995，26，2： | 1 |
| 5 | Patient-level meta-analysis: effect of measurement timing, threshold, and patient age on ability of D-dimer testing to assess recurrence risk after unprovoked venous thromboembolism显示文摘 | Douketis J Tosetto A Marcucci M | 2010 | Ann Intern Med2010，153，8： | 1 |
| 6 | Exprimental campaigns on textile wastewater for reuse by means of different membrane processes显示文摘 | Marcucci M Ciardelli G Matteucci A | 2002 | Desalination2002，149，： | 1 |
| 7 | Effects of free fatty acids on glucose transport and IRS-1 associated phosphatidylinositol 3-kinase activity显示文摘 | Laurent D Marcucci M | 1999 | J Clin Invest1999，103，2： | 1 |
| 8 | Free fatty acid-in- duced insulin resistance is associated with activation of protein ki- nase C theta and alterations in the insulin signaling cascade 显示文摘 | Griffin M E Marcucci M J Cline G W | 1999 | Diabetes1999，48，6： | 1 |
| 9 | Effects of free fatty acids on glucose transport and IRS-1-assiated phosphatidylinositol 3-kinase activity显示文摘 | Dresner A Laurent D Marcucci M | 1999 | J Clin Invest1999，103，： | 1 |
| 10 | MicroRNA expression in cytogenetically normal acute myeloid leukaemia 显示文摘 | Marcucci G Radmacher M D Maharry K | 2008 | N EnglJMed2008，358，18： | 1 |
| 11 | Phenolic compounds from Brazilian propolis with pharmacological activities显示文摘 | Marcucci M C Ferres F Garcia-Viguera | 2001 | Journal of Ethnophamacology2001，74，： | 1 |
| 12 | Effects of free fatty acids on glucose transport and IRS-l-associated phosphatidylinositol 3-kinase activity 显示文摘 | Dresner A Laurent D Marcucci M | 1999 | J Clin Invest1999，103，2： | 1 |
| 13 | Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade显示文摘 | Griffin M E Marcucci M J Cline G W | 1999 | Diabetes1999，48，： | 1 |
| 14 | Propolis: Chemical composition, biological properties and therapeutic activity 显示文摘 | MARCUCCI M C | 1995 | Apiologie1995，26，： | 1 |
| 15 | Treatment and reuse of textile effluents based on new ultrafiltration and other membrane technologies显示文摘 | | 2001 | Desalination2001，138，： | 1 |
| 16 | Propolis : Chemical Composition, Biological Properties and Therapeutic Activity 显示文摘 | Marcucci M C | 1995 | Apidologie1995，26，： | 1 |
| 17 | Free fatty acid induced insulin resistance is associated with activation of protein kinase C and alterations in the insulin signaling cascade显示文摘 | Griffin M E Marcucci M J Gary W | 1999 | DIABETES1999，48，： | 1 |
| 18 | Propolis-chemical composition, biological properties and therapeutic activity 显示文摘 | Marcucci M C | 1995 | Apidologie1995，26，： | 1 |
| 19 | Risk ofrecurrence after venous thromboembolism in men andwomen:patient level meta-analysis显示文摘 | DOUKETIS J TOSETTO A MARCUCCI M | 2011 | BMJ2011，342，： | 1 |
| 20 | Treatment and reuse of textile effluents based on new ultrafiltration and other membrane technologies显示文摘 | Marcucci M Nosenzo G Capannelli G | 2001 | Desalination2001，138，： | 1 |
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