|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Food groups, diet quality and colorectal cancer risk in the Basque Country显示文摘BACKGROUND The results obtained to date concerning food groups,diet quality and colorectal cancer(CRC)risk vary according to criteria used and the study populations.AIM To study the relationships between food groups,diet quality and CRC risk,in an adult population of the Basque Country(North of Spain).METHODS This observational study included 308 patients diagnosed with CRC and 308 ageand sex-matched subjects as controls.During recruitment,dietary,anthropometric,lifestyle,socioeconomic,demographic and health status information was collected.Adherence to the dietary recommendations was evaluated utilizing the Healthy Eating Index for the Spanish Diet and the MedDietScore.Conditional logistic regressions were used to evaluate the associations of food group intakes,diet quality scores,categorized in tertiles,with CRC risk.RESULTS The adjusted models for potential confounding factors showed a direct association between milk and dairy products consumption,in particular high-fat cheeses[odds ratio(OR)third tertile vs first tertile=1.87,95%confidence intervals(CI):1.11-3.16],and CRC risk.While the consumption of fiber-containing foods,especially whole grains(OR third tertile vs first tertile=0.62,95%CI:0.39-0.98),and fatty fish(OR third tertile vs first tertile=0.53,95%CI:0.27-0.99)was associated with a lower risk for CRC.Moreover,higher MD adherence was associated with a reduced CRC risk in adjusted models(OR third tertile vs first tertile=0.40,95%CI:0.20-0.80).CONCLUSION Direct associations were found for high-fat cheese,whereas an inverse relation was reported for fiber-containing foods and fatty fish,as well as adherence to a Mediterranean dietary pattern. | Iker Alegria-Lertxundi Carmelo Aguirre Luis Bujanda Francisco J Fernandez Francisco Polo JoseMªOrdovas MªCarmen Etxezarraga Inaki Zabalza Mikel Larzabal Isabel Portillo Marian M de Pancorbo Koldo Garcia-Etxebarria Ana MªRocandio Marta Arroyo-Izaga | 2020 | World Journal of Gastroenterology2020，26，28： | 3 |
| 2 | Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer:A systematic review of observational studies显示文摘BACKGROUND Dietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer(CRC).However,whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic regulators is still unclear.AIM To improve the current understanding of the molecular basis of CRC.METHODS A literature search in the Medline database,Reference Citation Analysis(http://gffzzb1f9d057b5954674sucb5wf5xvnf06o0w.ffgz.tsg.suse.edu.cn/),and manual reference screening were performed to identify observational studies published from inception to May 2022.RESULTS A total of fourteen case-control studies and five cohort studies were identified.These studies included information on dietary methyl donors,dietary components that potentially modulate the bioavailability of methyl groups,genetic variants of methyl metabolizing enzymes,and/or markers of CpG island methylator phenotype and/or microsatellite instability,and their possible interactions on CRC risk.CONCLUSION Several studies have suggested interactions between methylenetetrahydrofolate reductase polymorphisms,methyl donor nutrients(such as folate)and alcohol on CRC risk.Moreover,vitamin B6,niacin,and alcohol may affect CRC risk through not only genetic but also epigenetic regulation.Identification of specific mechanisms in these interactions associated with CRC may assist in developing targeted prevention strategies for individuals at the highest risk of developing CRC. | Lourdes Pilar Chávez-Hidalgo Silvia Martín-Fernández-de-Labastida Marian M de Pancorbo Marta Arroyo-Izaga | 2023 | World Journal of Gastroenterology2023，29，7： | 1 |
| 3 | Induction of male sterility in plants by a chimeric ribonuclease gene显示文摘 | Mariane C de Beuckeleer M Truettner J | 1990 | Nature1990，347，6295： | 1 |
| 4 | Induction of male sterility in plants by a chimaeric ribonuclease gene显示文摘 | MARIAN C De BEUCKELEER M TRUETTNER J LEEMANS J GOLDBERG R B | 1990 | Nature1990，347，： | 1 |
| 5 | Induction of male sterility in plants by a chimaeric ribonuclease gene 显示文摘 | Marian C De Beuekdeer M Truettner M | 1990 | Nature1990，347，： | 1 |
| 6 | Enzymatic recycling-based amperometric immunosensor for the ultrasensitive detection of okadaic acid in shellfish显示文摘 | Mònica Campàs Pablo de la Iglesia Marie Le Berre Marian Kane Jorge Diogène Jean-Louis Marty | 2008 | Biosensors and Bioelectronics2008，，4： | 1 |
| 7 | Immunogenicity and safety of a pneumococcal conjugate 7-valent vaccine in In- fants with Sickle Cell Disease 显示文摘 | Philippe R Malika B Mariane de M | 2007 | The Pediatric Infectious Dis- ease J2007，26，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员