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| 1 | HDL signaling and protection against coronary artery atherosclerosis in mice显示文摘Atherosclerosis is a leading underlying factor in cardiovascular disease and stroke,important causes of morbidity and mortality across the globe.Abundant epidemiological studies demonstrate that high levels of high density lipoprotein(HDL) are associated with reduced risk of atherosclerosis and preclinical,animal model studies demonstrate that this association is causative.Understanding the molecular mechanisms underlying the protective effects of HDL will allow more strategic approaches to development of HDL based therapeutics.Recent evidence suggests that an important aspect of the ability of HDL to protect against atherosclerosis is its ability to trigger signaling responses in a variety of target cells including endothelial cells and macrophages in the vessel wall.These signaling responses require the HDL receptor,scavenger receptor class B type 1(SR-B1),an adaptor protein(PDZK1) that binds to the cytosolic C terminus of SR-B1,Akt1 activation and(at least in endothelial cells) activation of endothelial NO synthase(eNOS).Mouse models of atherosclerosis,exemplified by apolipoprotein E or low density lipoprotein receptor gene inactivated mice(apoE or LDLR KO) develop atherosclerosis in their aortas but appear generally resistant to coronary artery atherosclerosis.On the other hand,inactivation of each of the components of HDL signaling(above)in either apoE or LDLR KO mice renders them susceptible to extensive coronary artery atherosclerosis suggesting that HDL signaling may play an important role in protection against coronary artery disease. | Bernardo L Trigatti Mark Fuller | 2016 | The Journal of Biomedical Research2016,30,2: | 8 |
| 2 | Excision of heterotopic ossification from the knee:a functional outcome study显示文摘 | Fuller DA Mark A Keenan MA | 2005 | Clin Orthop Relat Res2005,438,: | 1 |
| 3 | Bidding Strategies in a Bilateral Monopoly with Two-Sided Incomplete Information 显示文摘 | Rapoport Amnon Fuller Mark A | 1995 | Journal of Mathematical Psychology1995,39,2: | 1 |
| 4 | Collaborative Strategic Manage-ment :Strategy Formulation and Implementation by Multi-Or-ganizational Cross-Sector Social Partnerships 显示文摘 | Clarke Amelia Fuller Mark | 2010 | Journal ofBusiness Ethics2010,94,1: | 1 |
| 5 | Relative bioavailability of β-carotene from supplement sources显示文摘 | Cindy J Fuller Dale N Butterfoss Mark L Failla | 2001 | Nutrition Research2001,21,: | 1 |
| 6 | Excision of heterotopic ossifica- tion from the knee: a functional out 显示文摘 | Fuller DA Mark A Kneenan MA | 2005 | Clin Orthop Relat Res2005,,438: | 1 |
| 7 | Relative Bioavailability ofβ-carotene from supplement sources显示文摘 | Cindy J Fuller Dale N Butterfoss Mark L Failla | 2001 | Nutrition Research2001,21,: | 1 |
| 8 | Sub-Nyquist spectrum sensing and learning challenge显示文摘1 Introduction The fact that the spectrum resource is underutilised in certain bands has motivated the dynamic spectrum access(DSA)approach,which enables unlicensed secondary users(SUs)equipped with cognitive radio(CR)devices to access the spectrum without causing significant interference to primary users(PUs).Nowadays,the increasing bandwidth for wireless communication in millimetre-wave and Terahertz frequency bands puts higher requirements on the performance of spectrum sensing technique,the primary enabler of DSA. | Yue GAO Zihang SONG Han ZHANG Sean FULLER Andrew LAMBERT Zhinong YING Petri MAHONEN Yonina ELDAR Shuguang CUI Mark D.PLUMBLEY Clive PARINI Arumugam NALLANATHAN | 2021 | Frontiers of Computer Science2021,15,4: | 0 |
| 9 | Numerical evaluation on sub-Nyquist spectrum reconstruction methods显示文摘1 Introduction As wireless technology continues to expand,there is a growing concern about the efficient use of spectrum resources.Even though a significant portion of the spectrum is allocated to licensed primary users(PUs),studies indicate that their actual utilization is often limited to between 5%to 10%[1].The underutilization of spectrum has given rise to cognitive radio(CR)technology,which allows secondary users(SUs)to opportunistically access these underused resources[2].However,wideband spectrum sensing,the key of CR,is limited by the need for high-speed analog-to-digital converters(ADCs),which are costly and power-hungry.Compressed spectrum sensing(CSS)addresses this challenge by employing sub-Nyquist rate sampling.The efficiency of active transmission detection heavily depends on the quality of spectrum reconstruction. | Zihang SONG Han ZHANG Sean FULLER Andrew LAMBERT Zhinong YING Petri MAHONEN Yonina ELDAR Shuguang CUI Mark DPLUMBLEY Clive PARINI Arumugam NALLANATHAN Yue GAO | 2023 | Frontiers of Computer Science2023,17,6: | 0 |