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| 1 | Oxidative stress and male reproductive health显示文摘有缺点的精子功能的主要原因之一是氧化应力,它不仅破坏精子 DNA 的正直而且在精子血浆膜由于蛋白质和类脂化合物的并行的损坏限制这些房间的使肥沃的潜力。如此的氧化压力的起源看起来包含精子线粒体,它有一个趋势作为一篇序言产生 superoxide 阴离子的高水平到进入内在的 apoptotic 串联。不幸地,这些房间有很小的能力因为他们仅仅在基础切除修理(BER ) 拥有第一酶,对如此的攻击作出回应小径, 8-oxoguanine glycosylase 1 (OGG1 ) 。后者成功地创造一个 abasic 地点,而是精子因为他们缺乏下游的蛋白质,不能进一步处理氧化损害(APE1, XRCC1 ) 需要完成修理过程。在第一个有丝分裂的部门的 S 阶段的开始以前继续 BER 小径是卵母细胞的责任。如果一个错误被卵母细胞在开发的这个阶段犯,一个变化将被创造那将在身体在每个房间被代表。如此的机制可以在在作为年龄的后果在他们的细菌线承受了氧化应力的男性的后代观察的童年癌症和另外的疾病解释增加,环境或生活方式因素。在男不孕病人的精子的氧化 DNA 损坏的高流行可以为在 vitro 构思的孩子的健康有含意并且在细菌线为对免费激进的产生的起源的当前的研究担任一位司机。 | Robert J Aitken Tegan B Smith Matthew S Jobling Mark A Baker Geoffry N De Iuliis | 2014 | Asian Journal of Andrology2014，16，1： | 48 |
| 2 | Update on Cardiovascular Implantable Electronic Device Infections and Their Management: A Scientific Statement From the American Heart Association显示文摘 | Larry M. Baddour Andrew E. Epstein Christopher C. Erickson Bradley P. Knight Matthew E. Levison Peter B. Lockhart Frederick A. Masoudi Eric J. Okum Walter R. Wilson Lee B. Beerman Ann F. Bolger N A. Mark Estes Michael Gewitz Jane W. Newburger Eleanor B. S | 2010 | Circulation2010，，3： | 4 |
| 3 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010，，12： | 2 |
| 4 | 无心血管病者尿钠排泄、血压与未来心血管病及死亡风险显示文摘高血压是心血管病的危险因素。代表膳食钠摄入的尿钠排泄增加与血压相关。但在一些观察性研究中,低钠摄入与死亡率增加相关。进一步研究应评估混杂相关性是否能解释钠摄入与预后的关系。研究者分析英国生物银行参加者(n=457484,平均年龄56.3岁,44.7%为男性)尿电解质与血压的数据。采用Kawasaki公式估算每日尿钠排泄量。研究者分析基线无心血管病、治疗的高血压或糖尿病者(n=322624)钠排泄与血压的关系,并评估钠排泄与致死性及非致死性心血管病、心力衰竭及死亡发生率的关系。 | Welsh CE Welsh P Jhund P Delles C Celis-Morales C Lewsey JD Gray S Lyall D Iliodromiti S Gill JMR Sattar N Mark PB 赵狄 练桂丽 | 2019 | 中华高血压杂志2019，27，6： | 2 |
| 5 | Is There a Housing Crisis? The Incidence and Persistence of Housing Stress 2001 -2006 显示文摘 | Marks G N Sedgwick S T | 2008 | Australian Economic Review2008，41，02： | 1 |
| 6 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 7 | Hyperspectral imaging: an emerging technology as a potential novel adjunct in assessing peripheral peffusion deficits and success of lower extremity revaseularizations显示文摘 | OWEN N J III MARK S PETER K | 2008 | American College of Surgeons2008，207，3： | 1 |
| 8 | Characterization by LC-MSn of four new classes ofp-coumaric acid-containing diacyl chlorogenic acids in green coffee beans显示文摘 | CLIFFORD M N MARKS S KNIGHT S | | 0，，12： | 1 |
| 9 | Sudden cardiac death in athletes显示文摘 | Link M S Mark Estes N A 3rd | 2008 | Prog Cardiovasc Dis2008，51，： | 1 |
| 10 | The richmond agitation sedation scale validity and reliability in adult intensive care unit patients显示文摘 | CURTIS N SESSLER MARK S | 2002 | American Jonrnal of Respiratory and Critical Care Medicine2002，166，9： | 1 |
| 11 | Dual-curable unsaturated polyester inorganic/organic hybrid films显示文摘 | Ahmet N Teng G H Mark D S | 2006 | Journal of Applied Polymer Science2006，99，1： | 1 |
| 12 | The richmond agitation-sedation scale validity and reliability in adult intensive care unit patients 显示文摘 | Curtis N Sessler Mark S | 2002 | American Jonrnal of Respiratory and Critical Care Medi- cine2002，166，10： | 1 |
| 13 | Structure-property relationship of all-cellulose composites 显示文摘 | BENO J C ROGER H N MARK P S | 2009 | Comp Sci Tech2009，69，： | 1 |
| 14 | Measurement of liver fat by MRI and its reduction by dexfenfluramine in NIDDM显示文摘 | Marks S J Moore N R Ryley N G | 1997 | Int J Obes Relat Metab Disord1997，21，4： | 1 |
| 15 | Resistance modelling of ammonia exchange over oilseed rape 显示文摘 | Eiko N Mark A S Jan K S | 2000 | Agricultural and Forest Meteorology2000，105，： | 1 |
| 16 | Three-dimensional analysis of subwavelength diffractive optical elements with the finite-difference time-domain method显示文摘 | Dennis W Prather Joseph N Mait | 2000 | Applied Optics2000，39，6： | 1 |
| 17 | Data Mining Methods,Applications and Tools 显示文摘 | Chen L D Toru S Mark N F | 2000 | Information System Management2000，17，1： | 1 |
| 18 | Review: finishing and polishing procedures of (resin-modified) glass ionomers and compomers in paediatric dentistry显示文摘 | Koupis N S Marks L A Verbeeck R M | 2007 | Eur Arch Paediatr Dent2007，8，1： | 1 |
| 19 | Size effects in axially loaded square-section concrete prisms strengthened using carbon fiber reinforced polymer wrapping 显示文摘 | MARK J M TREVOR N G NIGEL G S | 2004 | Canadian Journal of Civil Engineering2004，35，4： | 1 |
| 20 | Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial显示文摘 | Edward J Gane Stuart K Roberts Catherine AM Stedman Peter W Angus Brett Ritchie Rob Elston David Ipe Peter N Morcos Linda Baher Isabel Najera Tom Chu Uri Lopatin M Michelle Berrey William Bradford Mark Laughlin Nancy S Shulman Patrick F Smith | 2010 | The Lancet2010，，9751： | 1 |
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