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| 1 | Orthotopic liver transplantation for giant liver haemangioma: A case report显示文摘In liver haemangiomas, the risk of complication rises with increasing size, and treatment can be obligatory. Here we present a case of a 46-year-old female who suffered from a giant haemangioma causing severe portal hypertension and vena cava compression, leading to therapy refractory ascites, hyponatremia and venostasis-associated thrombosis with pulmonary embolism. The patients did not experience tumour rupture or consumptive coagulopathy. Surgical resection was impossible because of steatosis of the non-affected liver. Orthotopic liver transplantation was identified as the only treatment option. The patient's renal function remained stable even though progressive morbidity and organ allocation were improbable according to the patient's lab model for end-stage liver disease(lab MELD) score. Therefore, non-standard exception status was approved by the European organ allocation network 'Eurotransplant'. The patient underwent successful orthotopic liver transplantation 16 mo after admission to our centre. Our case report indicates the underrepresentation of morbidity associated with refractory ascites in the lab MELD-based transplant allocation system, and it indicates the necessity of promptly applying for non-standard exception status to enable transplantation in patients with a severe clinical condition but low lab MELD score. Our case highlights the fact that liver transplantation should be considered early in patients with non-resectable, symptomatic benign liver tumours. | Undine G Lange Julian N Bucher Markus B Schoenberg Christian Benzing Moritz Schmelzle Tanja Gradistanac Steffen Strocka Hans-Michael Hau Michael Bartels | 2015 | World Journal of Transplantation2015，5，4： | 6 |
| 2 | Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization显示文摘血管肉瘤是有差的预后的肝的一个稀罕的主要的恶意的瘤。这里,我们与被紧急情况对待的一个破裂的肝的血管肉瘤报导一个病人的一个案例指导导管的 embolization,由左边的偏身出汗列在后面。 | Christine Leowardi Yura Hormann UIf Hinz Moritz N Wente Peter Hallscheidt Christa Flechtenmacher Markus W Büchler Helmut Friess Matthias HM Schwarzbach | 2006 | World Journal of Gastroenterology2006，12，5： | 4 |
| 3 | Achalasia: will genetic studies provide insights?显示文摘 | Henning R. Gockel Johannes Schumacher Ines Gockel Hauke Lang Thomas Haaf Markus M. N?then | 2010 | Human Genetics2010，，4： | 3 |
| 4 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 5 | A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection显示文摘 | Luca Formichella Laura Romberg Christian Bolz Michael Vieth Michael Geppert Gereon G?ttner Christina N?lting Dirk Walter Wolfgang Schepp Arne Schneider Kurt Ulm Petra Wolf Dirk H. Busch Erwin Soutschek Markus Gerhard | 2013 | Clinical and Vaccine Immunology2013，，11： | 2 |
| 6 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study显示文摘 | Andri Rauch Zoltán Kutalik Patrick Descombes Tao Cai Julia Di Iulio Tobias Mueller Murielle Bochud Manuel Battegay Enos Bernasconi Jan Borovicka Sara Colombo Andreas Cerny Jean–Fran?ois Dufour Hansjakob Furrer Huldrych F. Günthard Markus Heim Bernard Hirs | 2010 | Gastroenterology2010，，4： | 2 |
| 7 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 8 | Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing显示文摘The impact of the microenvironment on innate lymphoid cell(ILC)-mediated immunity in humans remains largely unknown.Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcriptional profiles and heterogeneity of CD127+ILCs across four human tissues.Correlation analysis identified gene modules characterizing the migratory properties of tonsil and blood ILCs,and signatures of tissue-residency,activation and modified metabolism in colon and lung ILCs.Trajectory analysis revealed potential differentiation pathways from circulating and tissue-resident naïve ILCs to a spectrum of mature ILC subsets.In the lung we identified both CRTH2+and CRTH2−ILC2 with lung-specific signatures,which could be recapitulated by alarmin-exposure of circulating ILC2.Finally,we describe unique TCR-V(D)J-rearrangement patterns of blood ILC1-like cells,revealing a subset of potentially immature ILCs with TCR-δ rearrangement.Our study provides a useful resource for in-depth understanding of ILC-mediated immunity in humans,with implications for disease. | Luca Mazzurana Paulo Czarnewski Viktor Jonsson Leif Wigge Markus Ringnér Teresa CWilliams Avinash Ravindran Åsa KBjörklund Jesper Säfholm Gunnar Nilsson Sven-Erik Dahlén Ann-Charlotte Orre Mamdoh Al-Ameri Charlotte Höög Charlotte Hedin Sylwester Szczegielniak Sven Almer Jenny Mjösberg | 2021 | Cell Research2021，31，5： | 2 |
| 9 | Apolipoprotein M is required for pre -HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | Christian Wolfrum Matthew N Poy Markus Stoffel | 2005 | Nature Medicine2005，11，4： | 1 |
| 10 | Associationbetween infection with Helicobacter pylori and chlamydia pneumoniae and risk of ischemie stroke subtypes results from a population-based case-control study显示文摘 | PETER UH DANIEL N MARKUS G | 2001 | Stroke2001，32，5： | 1 |
| 11 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet . 2012 (9859)2012，，9859： | 1 |
| 12 | Ubiquitous service access through adapted user interfaces on multiple devices显示文摘 | Stina N Markus B Annika W | 2005 | Personal and Ubiquitous Computing2005，9，3： | 1 |
| 13 | Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-κB, and STAT3 signaling pathways显示文摘 | JOSEF W MARKUS N JOHANNA W | 2009 | American Journal of Physiology-Gastrointestinal and Liver Physiology2009，297，： | 1 |
| 14 | Prognostic value of preoperative cardiac troponin I in patients undergoing emergency coronary artery bypass surgery with non-ST-elevation or ST-elevation acute coronary syndromes显示文摘 | MATTHIAS T PARWIS M MARKUS N | 2006 | Circulation2006，114，： | 1 |
| 15 | Lotus-effects-surfaces显示文摘 | Edwin N Markus O | 2002 | Macromol Symp2002，187，： | 1 |
| 16 | Satellite observations of Antarctic sea ice thickness and volume 显示文摘 | Kurtz N T Markus T | 2012 | Journal of Geophysical Research2012，117，08： | 1 |
| 17 | Satellite observations of Antarctic sea ice thickness and volume显示文摘 | Kurtz N T Markus T | 2012 | Journal of Geophysical Research2012，117，08： | 1 |
| 18 | Detoxification of wood hydrolysates with wood charcoal for increasing the fermentability of hydrolysates显示文摘 | Hisashi M Herbert D Markus N | 2003 | Enzyme and Microbial Technology2003，32，： | 1 |
| 19 | Optical systems with high-order DPSK and star QAM modulation based on interferometric direct detection显示文摘 | MATTHIAS S MARKUS N ERWlN P | 2007 | Journal of Lightwave Technology2007，25，6： | 1 |
| 20 | A common polymorphism in the methyleneterahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease显示文摘 | Markus HS All N Swaminathan R | 1997 | Stroke1997，28，9： | 1 |
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