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| 1 | Hepatic intra-arterial infusion of yttrium-90 microspheres in the treatment of recurrent hepatocellular carcinoma after liver transplantation: A case report显示文摘Hepatocellular carcinoma (HCC) recurs with a reported frequency of 12%-18% after liver transplantation. Recurrence is associated with a mortality rate exceeding 75%. Approximately one-third of recurrences develop in the transplanted liver and are therefore amenable to local therapy. A variety of treatment modalities have been reported including resection, transarterial chemo- embolization (TACE), radiofrequency ablation (RFA), ethanol ablation, cryoablation, and external beam irradiation. Goals of treatment are tumor control and the minimization of toxic effect to functional parenchyma. Efficacy of treatment is mitigated by the need for ongoing immunosuppression. Yttrium-90 microspheres have been used as a treatment modality both for primary HCC and for pre-transplant management of HCC with promising results. Twenty-two months after liver transplantation for hepatitis C cirrhosis complicated by HCC, a 42-year old man developed recurrence of HCC in his transplant allograft. Treatment of multiple right lobe lesions with anatomic resection and adjuvant chemotherapy was unsuccessful. Multifocal recurrence in the remaining liver allograft was treated with hepatic intra-arterial infusion of yttrium-90 microspheres (SIR-Spheres, Sirtex Medica Inc., Lake Forest, IL, USA). Efficacy was demonstrated by tumor necrosis on imaging and a decrease in alpha-fetoprotein (AFP) level. There were no adverse consequences of initial treatment. | Louis Rivera Huan Giap William Miller Jonathan Fisher Donald J Hillebrand Christopher Marsh Randolph L Schaffer | 2006 | World Journal of Gastroenterology2006，12，35： | 6 |
| 2 | The Changing Cold Regions Network:Observation,diagnosis and prediction of environmental change in the Saskatchewan and Mackenzie River Basins,Canada显示文摘Climate change is causing rapid and severe changes to many Earth systems and processes,with widespread cryospheric,ecological,and hydrological impacts globally,and especially in high northern latitudes.This is of major societal concern and there is an urgent need for improved understanding and predictive tools for environmental management.The Changing Cold Regions Network(CCRN)is a Canadian research consortium with a focus to integrate existing and new experimental data with modelling and remote sensing products to understand,diagnose,and predict changing land,water,and climate,and their interactions and feedbacks over the geographic domain of the Mackenzie and Saskatchewan River Basins in Canada.The network operates a set of 14 unique and focused Water,Ecosystem,Cryosphere and Climate(WECC)observatories within this region,which provide opportunities to observe and understand processes and their interaction,as well as develop and test numerical simulation models,and provide validation data for remote sensing products.This paper describes this network and its observational,experimental,and modelling programme.An overview of many of the recent Earth system changes observed across the study region is provided,and some local insights from WECC observatories that may partly explain regional patterns and trends are described.Several of the model products being developed are discussed,and linkages with the local to international user community are reviewed—In particular,the use of WECC data towards model and remote sensing product calibration and validation is highlighted.Some future activities and prospects for the network are also presented at the end of the paper. | Chris M DEBEER Howard S WHEATER William L QUINTON Sean K CAREY Ronald E STEWART Murray D MACKAY Philip MARSH | 2015 | Science China Earth Sciences2015，58，1： | 5 |
| 3 | Effects of grading leniency and low workload on students' evaluations of teaching: popular myth, bias, validity, or innocent by standers显示文摘 | Roche L A | 2002 | Journal of Educational Psychology2002，92，1： | 1 |
| 4 | Terminal restriction fragment length polymorphism an analysis program,a web-based research tool for microbial community analysis显示文摘 | Marsh T L Saxman P Cole J | 2000 | Appl Environ Microbiol2000，66，8： | 1 |
| 5 | Structural evolution and conductivity of PEO: LiBF4-MgO composite electrolytes显示文摘 | Kmnar B Scanlon L Marsh R | 2001 | Electrockimica Acta2001，46，1011： | 1 |
| 6 | 显示文摘 | Rieke P C Marsh B D Wood M L | 1995 | Langmuir1995，11，1： | 1 |
| 7 | Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer显示文摘 | Dawson LA Anzai Y Marsh L | 2000 | lnt J Radiat Oncol Biol Phys2000，46，5： | 1 |
| 8 | The application of polymer crystal growth theory to be kinetics of formation of the 13-amylose polymoph in a 50% wheat-starch gel显示文摘 | MARSH D L BLANSHARD J M V | 1988 | Carbonhydrate Polymers1988，8，： | 1 |
| 9 | Neuropsychiatric aspects of Parkinson' s disease显示文摘 | Marsh L | | 0，，： | 1 |
| 10 | An experimental study on the effect of ultrasonication on viscosity and heat transfer performance of multi-wall carbonnanotube-based aqueous nanofluids 显示文摘 | Garg P Alvarado J L Marsh C | 2009 | International Journal of Heat and Mass Transfer2009，52，21： | 1 |
| 11 | Neuropsychiatric symptoms in Parkinson's disease显示文摘 | Aarsland D Marsh L Schrag A | 2009 | Mov Disord2009，24，15： | 1 |
| 12 | Myocardial Infarction in young patients显示文摘 | Choudhury L Marsh JD | 1999 | Am J Med1999，107，3： | 1 |
| 13 | 显示文摘 | MUNICHANDRAIAH N SCANLON L G MARSH R A | 1995 | J Appl Electrochem1995，25，9： | 1 |
| 14 | Characterization of microbial diversity by determining terminal restriction fragment length polymorphisms of genes encoding 16S rRNA显示文摘 | Liu W T Marsh T L Cheng H | 1997 | Applied and Environmental Microbiology1997，63，11： | 1 |
| 15 | Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma显示文摘 | Holcombe R F Marsh J L Waterman M L | 2002 | Mol Pathol2002，55，4： | 1 |
| 16 | Effects of grading leniency and low workload on students' evaluation of teaching: popular myth, bias, validity or innocent bystanders? 显示文摘 | MARSH H W ROCHE L A | 2000 | Journal of Educational Psychology2000，，92： | 1 |
| 17 | Characterization of microbial diversity determining terminal restrictionfragment length polymorphisms of genes encoding 16S RNA 显示文摘 | Liu W T Marsh T L Cheng H | 1997 | Appl Envion Microbiol1997，63，： | 1 |
| 18 | Characterization of microbial diversity by determining terminal restriction fragment length polymorphisms of genes encoding 16S rRNA显示文摘 | LIU W T MARSH T L CHENG H | 1997 | Appl Environ Mierobiol1997，63，11： | 1 |
| 19 | endometrial endothelin:regulator of uterine bleeding and endometriar repair 显示文摘 | Salamonsen L A Marsh M M | 1999 | Clin Exp Pharm Physi Cal1999，26，2： | 1 |
| 20 | A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer 显示文摘 | Winsey S L Haldar N A Marsh H P | 2000 | Cancer Res2000，60，20： | 1 |
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