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您的检索式：作者名="Masayasu Horibe"
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| 1 | Superiority of urgent vs early endoscopic hemostasis in patients with upper gastrointestinal bleeding with high-risk stigmata显示文摘Background Guidelines recommend that all patients with upper gastrointestinal bleeding(UGIB)undergo endoscopy within 24 h.It is unclear whether a subgroup may benefit from an urgent intervention.We aimed to evaluate the influence of endoscopic hemostasis and urgent endoscopy on mortality in UGIB patients with high-risk stigmata(HRS).Methods Consecutive patients with suspected UGIB were enrolled in three Japanese hospitals with a policy to perform endoscopy within 24 h.The primary outcome was 30-day mortality.Endoscopic hemostasis and endoscopy timing(urgent,6h;early,>6h)were evaluated in a regression model adjusting for age,systolic pressure,heart rate,hemoglobin,creatinine,and variceal bleeding in multivariate analysis.A propensity score of 1:1 matched sensitivity analysis was also performed.Results HRS were present in 886 of 1966 patients,and 35 of 886(3.95%)patients perished.Median urgent-endoscopy time(n=769)was 3.0h(interquartile range[IQR],2.0–4.0 h)and early endoscopy(n紏117)was 12.0h(IQR,8.5–19.0 h).Successful endoscopic hemostasis and urgent endoscopy were significantly associated with reduced mortality in multivariable analysis(odds ratio[OR],0.22;95%confidence interval[CI],0.09–0.52;P=0.0006,and OR,0.37;95%CI,0.16–0.87;P=0.023,respectively).In a propensity-score-matched analysis of 115 pairs,adjusted comparisons showed significantly lower mortality of urgent vs early endoscopy(2.61%vs 7.83%,P<0.001).Conclusions A subgroup of UGIB patients,namely those harboring HRS,may benefit from endoscopic hemostasis and urgent endoscopy rather than early endoscopy in reducing mortality.Implementing triage scores that predict the presence of such lesions is important. | Masayasu Horibe Eisuke Iwasaki Juntaro Matsuzaki Fateh Bazerbachi Tetsuji Kaneko Kazuhiro Minami Seiichiro Fukuhara Tatsuhiro Masaoka Naoki Hosoe Yuki Ogura Shin Namiki Yasuo Hosoda Haruhiko Ogata Takanori Kanai | 2021 | Gastroenterology Report2021，9，6： | 0 |
| 2 | Horibe胃肠出血预测评分(HARBINGER)用于上消化道出血重症患者的内镜治疗效果的预测显示文摘We read with great interest the study by Rao et al.[1]Rao and colleagues showed that the Rockall score,Glasgow-Blatchford score(GBS)and AIMS65 are poorly predictive of 30-day mortality,or the need for endoscopic intervention in intensive care unit(ICU)patients with an upper GI bleed(UGIB).The Rockall[2]score and AIMS65[3]were developed for predicting mortality,whereas the GBS[4]was developed for predicting composite outcomes(The need for a blood transfusion or intervention to control bleeding,rebleeding,or death)We were not surprised to see that these scores were poor predictors of endoscopic intervention,as they were not designed to predict high-risk endoscopic stigmata(HRS),which is arguably a very meaningful endpoint to determine the need for endoscopic intervention. | Fateh Bazerbachi Masayasu Horibe | 2021 | Gastroenterology Report2021，9，1： | 0 |
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