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| 1 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012,18,12: | 2 |
| 2 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013,22,: | 1 |
| 3 | Broadband MIMO-OFDM wireless communications 显示文摘 | Stnber G L Barry J R McLaughlin S W | 2004 | Proceedings of the IEEE2004,92,2: | 1 |
| 4 | Smoking and drinking in relation to oral and pha- ryngeal cancer显示文摘 | BLOT W J MCLAUGHLIN J K WINN D M | 1988 | Cancer Res1988,48,: | 1 |
| 5 | Alkaloids in whole plant material:Direct analysis by kinetic energy spectrometry 显示文摘 | Kondrat R W Cooks R Q McLaughlin J L | 1978 | Science1978,199,4332: | 1 |
| 6 | Temporal trends of total and potentially available element concentrations in sewage biosolids: a comparison of biosolid surveys conduc- ted 18 years apart显示文摘 | Oliver I W McLaughlin M J Merrington G | 2005 | Science of The Total Environment2005,337,13: | 1 |
| 7 | Broadband MIMO-OFDM wireless communications显示文摘 | STUBER G L BARRY J R MCLAUGHLIN S W | 2004 | Proceedings of the IEEE2004,92,2: | 1 |
| 8 | Job performance deficits due to depression 显示文摘 | Adler D A McLaughlin T J Rogers W H | 2006 | Am J Psychiatry2006,163,: | 1 |
| 9 | Applying GLOBE measure- ments and resources to the study of marine environments显示文摘 | McLaughlin J W Henderson S | 2005 | Oceans2005,,3: | 1 |
| 10 | Broadband MIMO-OFDM wireless communications显示文摘 | Stuber G L Barry J R Mclaughlin S W | 2004 | Proceedings of the IEEE2004,92,2: | 1 |
| 11 | Evalua-tion of the developmental toxicities of ethanol,acetal-dehyde,and thioacetamide using FETAX显示文摘 | Fort D J McLaughlin D W Rogers R L | 2003 | Drug and Chemical Toxicology2003,26,1: | 1 |
| 12 | Effect of endo- crine disrupting chemicals on germinal vesicle break- down in Xenopus in vitro 显示文摘 | Fort D J McLaughlin D W Rogers R L | 2002 | Drug and Chemical Toxi- cology2002,25,3: | 1 |
| 13 | Biodegradation of Rhamnolipid, EDTA and Citric Acid in Cadmium and Zinc Con- taminated Soils 显示文摘 | JIA W STACEY S P MCLAUGHLIN M J | 2009 | Soil Biology and Biochemistry2009,41,10: | 1 |
| 14 | Plasma actuator force measurements显示文摘 | Porter C O Baughn J W McLaughlin T E | 2007 | AIAA Journal2007,45,7: | 1 |
| 15 | Temperature and relative humidity dependence of radiochromic film dosimeter response to gamma and electron radiation显示文摘 | Mclaughlin W L Puhi J M Miller A | 1995 | Radiation Phys Chem1995,46,46: | 1 |
| 16 | Quantification of selected vapour-phasecompounds using thermal desorption-gas chromatography 显示文摘 | McLaughlin D W J Bell R E Graham D J | 2004 | Beitr Tabakforsch Int2004,21,: | 1 |
| 17 | Broadband MIMO-OFDM wireless communications显示文摘 | Stuber G L Barry J R Mclaughlin S W etal | 2004 | Proceedings of the IEEE2004,92,2: | 1 |
| 18 | Rate-compatible punctu- ring of low-density parity-check codes 显示文摘 | Ha J McLaughlin S W | 2004 | IEEE Trans Inform Theory2004,50,11: | 1 |
| 19 | Broadband MIMO-OFDM Wireless Communications 显示文摘 | Stuber G L Barry J R Mclaughlin S W | 2004 | Proceedings of the IEEE2004,92,2: | 1 |
| 20 | Having fun at workr显示文摘 | Ford R C McLaughlin F S and Newstrom J W | 2004 | Engineering Management2004,14,2: | 1 |