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| 1 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 2 | Bias correction for individual realization laser Doppler measurements in turbulent flows显示文摘 | Tiedermann W G | 1973 | Phys of Fluids1973，16，： | 1 |
| 3 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 4 | A restricted Backlund transformation 显示文摘 | MCLAUGHLIN D W SCOTT A C | 1973 | J Math Phys1973，14，12： | 1 |
| 5 | Smoking and drinking in relation to oral and pha- ryngeal cancer显示文摘 | BLOT W J MCLAUGHLIN J K WINN D M | 1988 | Cancer Res1988，48，： | 1 |
| 6 | Job performance deficits due to depression 显示文摘 | Adler D A McLaughlin T J Rogers W H | 2006 | Am J Psychiatry2006，163，： | 1 |
| 7 | Treatment of nasopharyngeal papillomatosis with coblation:a case series显示文摘 | PETERS G MCLAUGHLIN K NUSS D W | 2011 | Int Forum Allergy Rhinol2011，1，： | 1 |
| 8 | Evalua-tion of the developmental toxicities of ethanol,acetal-dehyde,and thioacetamide using FETAX显示文摘 | Fort D J McLaughlin D W Rogers R L | 2003 | Drug and Chemical Toxicology2003，26，1： | 1 |
| 9 | Effect of endo- crine disrupting chemicals on germinal vesicle break- down in Xenopus in vitro 显示文摘 | Fort D J McLaughlin D W Rogers R L | 2002 | Drug and Chemical Toxi- cology2002，25，3： | 1 |
| 10 | Quantification of selected vapour-phasecompounds using thermal desorption-gas chromatography 显示文摘 | McLaughlin D W J Bell R E Graham D J | 2004 | Beitr Tabakforsch Int2004，21，： | 1 |
| 11 | Genome sequence of Streptococcus mutans UA159,a cariogenic dental pathogen 显示文摘 | Ajdic D McShan W M McLaughlin R E Savie G Chang J Carson M B | 2002 | Proc Natl Aead Sci USA2002，99，14： | 1 |
| 12 | Persistent homoclinic orbits for a perturbed nonlinear Schr(o)dinger equation显示文摘 | Li Y Mclaughlin D W Shatahm J | 1996 | Pure Appl Math1996，49，11： | 1 |
| 13 | Foliar amino acid accumulation as an indicator of ecosystem stress for flint - year sugar maple seedlings 显示文摘 | McLaughlin J W Reed D D Bagley S T | 1994 | Journal of Environmental Quality1994，23，： | 1 |
| 14 | Soil factors related to dissolved organic carbon concentrations in a black spruce swamp Michigan显示文摘 | Mclaughlin J W Lewin J C Reed D | 1994 | Soil Science1994，158，6： | 1 |
| 15 | Single-stage antero-posterior decompression and stabilization for complex cervical spine disorder显示文摘 | Schultz K D Mclaughlin M R Haid R W | 2000 | J Neurosurg2000，93，2： | 1 |
| 16 | A Model of Consumer Perceptions and Store Loyalty Intentions for a Supermarket Retailer显示文摘 | SIROHI N MCLAUGHLIN E W WITTINK D R | 1998 | Journal of Retailing1998，74，4： | 1 |
| 17 | Direct Approach to Study of Soliton Pertrubations of the Generalized Kdv Equation显示文摘 | Keener J P McLaughlin D W | 1977 | Phys Rev A1977，16，： | 1 |
| 18 | Direct Approach to Study of Soliton Perturbations of the Generalized Kdv Equation显示文摘 | Keener J P McLaughlin D W | 1977 | J Math Phys1977，18，： | 1 |
| 19 | Broadband MIMO-OFDM wireless communications显示文摘 | SG L tuber R Barry S W Mclaughlin Li Ye D Brunelli and T G Pratt | | 0，，02： | 1 |
| 20 | Persistent homoclinic orbits for perturbed nonlinear Schrodinger equations显示文摘 | Li Y Mclaughlin D W Q Shatan J | 1996 | Comm Pure Appl Math1996，49，1： | 1 |
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