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7篇 您的检索式:作者名="Mechi R"
    题名 作者 年代 出处 被引量
1Extension of the zonal method to inhomogeneous non-grey semi-transparent medium 显示文摘Mechi R Farhat H Guedri K 2010Energy2010,35,1:1
2Lithospheric and upper mantle structure of southern Tibet from a seismo logical passive source experiment显示文摘Yuan X Ni J Kind R Mechie J Sandolev E 1997J Geophys Res1997,102,27:1
3The seismological structure of the Tibet- an Plateau crust and mantle down to 700 km depth显示文摘Mechie J Kind R Saul J 2011Geolog- ical Society of London2011,353,:1
4Seismic mapping of crustal structures beneath the Indus-Yarlung Suture, Tibet显示文摘Zhao W Mechie J Guol J Wenzel F Meissner R Ratschbacher L Steentoft H Husen S 1997Terra Nova1997,9,2:1
5Predictability of IL-28B-polymorphism on protease-inhibitor-based triple-therapy in chronic HCV-genotype-1 patients: A meta-analysis显示文摘AIM: To investigate the predictability of interleukin-28 B single nucleotide polymorphism rs12979860 with respect to sustained virological response(SVR) in chronically hepatitis C virus(HCV) genotype-1 patients treated with a protease-inhibitor and pegylated interferon-α(Peg-INF-α) based triple-therapy. METHODS: We searched PubMed, the Cochrane Library and Web of Knowledge for studies regarding the interleukin 28B(IL-28B)-genotype and protease-inhibitor based triple-therapy. Ten studies with 2707 patients were included into this meta-analysis. We used regression methods in order to investigate determinants of SVR.RESULTS: IL-28B-CC-genotype patients achieved higher SVR rates(odds 5.34, 95%CI: 3.81-7.49) than IL-28B-non-CC-genotype patients(1.88, 95%CI: 1.43-2.48) receiving triple-therapy. The line of therapy(treatment-nave or-experienced for Peg-INF-α) did not affect the predictive value of IL-28B(P = 0.1). IL-28BCC-genotype patients treated with protease inhibitorbased triple-therapy consisting of Boceprevir, Simeprevir, Telaprevir or Vaniprevir showed odds of 3.38, 14.66, 7.84 and 2.91, respectively. The odds for CC genotype patients treated with Faldaprevir cannot be quantified, as only a single study with a 100% SVR rate was available.CONCLUSION: IL-28B-SNP predicts the outcome for chronic HCV genotype-1 patients receiving protease inhibitor-based triple-therapy. The predictive value varies between the different protease inhibitors.Nicolae-Catalin Mechie Christian Rver Silke Cameron Ahmad Amanzada 2014World Journal of Hepatology2014,6,10:1
6Lithospheric and upper mantle structure of southern Tibet form a seismological passive source experiment 显示文摘Yuan X Ni J Kind R Mechie J Sandvol E 1997Journal of Geophysical Research1997,102,27:1
7INDEPTH Ⅲ seismic data:From surface observations to deep crustal processes in Tibet显示文摘Haines S.S Klemperer S.L Brown L Jingru G Mechie J Meissner R Ross A Wenjin Z Tectonics0,,:1
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