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| 1 | S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3显示文摘建筑群由 S100 钙绑定蛋白质家庭,的二个成员形成了 S100A8/A9,在不同起源的各种各样的房间施加导致 apoptosis 活动。这里,我们内在的分子的机制包含的现在的证据两个都规划了房间死亡我(PCD 我, apoptosis ) 并且象死亡一样的 PCD II (autophagy ) 。有 S100A8/A9 的房间的处理引起了 Beclin-1 表示以及 Atg12-Atg5 形成的增加。S100A8/A9-induced 房间死亡被特定的 PI3-kinase 班 III 禁止者部分禁止, 3-methyladenine (3 麻省) ,并且由液泡 H+-ATPase 禁止者, bafilomycin-A1 (Baf-A1 ) 。S100A8/A9 挑起了 BNIP3 的 translocation, BH3 仅仅 pro-apoptotic Bcl2 家庭成员,到线粒体。与这发现一致,螖 T M-BNIP3 overexpression 部分禁止了 S100A8/A9-induced 细胞死亡,减少的反应的氧种(ROS ) 产生,并且部分在 S100A8/A9-treated 细胞在 mitochondrial transmembrane 潜力免于减少。另外,任何一个螖 T M-BNIP3 overexpression 或 N-acetyl-L-cysteine 合作处理减少了在与 S100A8/A9 对待的房间的 lysosomal 激活。我们的数据显示 S100A8/A9-promoted 房间死亡通过线粒体的串音发生,经由 ROS 和这个过程的 lysosomes 包含 BNIP3。 | Saeid Ghavami Mehdi Eshragi Sudharsana R Ande Walter J Chazin Thomas Klonisch Andrew J Halayko Karol D Mcneill Mohammad Hashemi Claus Kerkhoff Marek Los | 2010 | Cell Research2010，20，3： | 13 |
| 2 | HALOMETHYLATION OF POLYSTYRENE AND SUBSEQUENT PYRIDINATION VIA A HOMOLYTIC PATHWAY显示文摘Chloromethylation of polystyrene (PS) with two different chloromethylating systems methylal/thionyl chloride and paraformaldehyde/trimethylchlorosilane was studied. Soluble chloromethylated polystyrene with a degree of substitution of 89% was obtained. The Conant-Finkelstein reaction on the chloromethylated PS afforded soluble iodomethylated polystyrene with a degree of substitution as high as 96%. The reaction conditions of Minisci were employed to radically pyridinate PS via its iodomethylated derivative. Polyelectrolytes were formed which could be converted to normal polymers by treatment with a 20% aqueous solution of NaOH. | Sad Moulay Nadia Mehdi | 2006 | Chinese Journal of Polymer Science2006，24，6： | 3 |
| 3 | Impaired expression of peroxisome proliferator-activated receptor γ in ulcerative colitis显示文摘 | Laurent Dubuquoy Emmelie ? Jansson Samir Deeb Sabine Rakotobe Mehdi Karoui Jean-Frédéric Colombel Johan Auwerx Sven Pettersson Pierre Desreumaux | 2003 | Gastroenterology2003，，5： | 2 |
| 4 | An empirical study on the influence of environmental labels on consumers 显示文摘 | Clare D' Souza Mehdi Taghian Peter Lamb | 2006 | Corporate Communications: An International Journal2006，11，2： | 1 |
| 5 | Robust stability and stabilization of a class of singular systems with multiple time varying delays显示文摘 | Saadni S M Chaabane M Mehdi D | 2006 | Asian J of Control2006，8，1： | 1 |
| 6 | Serological survey ofToxoplasma gondii in schizophrenia patients referred to Psychi-atric Hospital,Sari City,Iran显示文摘 | Ahmad D Mehdi S Sayed HH | 2010 | Trop Biomed2010，27，3： | 1 |
| 7 | Distributed topology control algorithm based on one-and two-hop neighbors' information for ad hoc networks 显示文摘 | Mehdi K Shiri M E Mehdi D | 2009 | Computer Communications2009，32，2： | 1 |
| 8 | Direct numerical method for an inverse problem of a parabolic parical differential equation显示文摘 | Liao Wenyuan Mehdi D Akbar M | 2009 | Journal of Computational and Applied Mathematics2009，3232，： | 1 |
| 9 | Robustness and Optimality of Linear Quadratic Controller for Uncertain Systems显示文摘 | Mehdi D Mohammed A H Francois P | 1996 | Automatic1996，32，7： | 1 |
| 10 | Robust stabilization for uncertain time-varying delay constrained systems with delay-dependence显示文摘 | HAN Q L MEHDI D | 1999 | Applied Mathematics and Computer Science1999，9，2： | 1 |
| 11 | Imidazolium ionic liquids as solvents for cerium (IV) -mediated oxidation reactions 显示文摘 | MEHDI H BODOR A LANTOS D | 2007 | Journal of Organic Chemistry2007，72，2： | 1 |
| 12 | Finite iterative algorithms for the reflexive and anti-reflexive solutions of the matrix equation A1X1B1+ A2X2B2 =C显示文摘 | Mehdi D Masoud H | | 0，，： | 1 |
| 13 | Comments on robust control for parameter uncertain delay systems in state and control input显示文摘 | Han Q L Mehdi D | 1998 | Automatica1998，32，12： | 1 |
| 14 | Adverse associations between CX3CR1 polymorphisms and risk of cardiovascular or cerebrovascular disease显示文摘 | Elise L Julien L Mehdi D | 2005 | Arterioscler Thromb Vasc Biol2005，25，： | 1 |
| 15 | An iterative method for solving the generalized coupled Sylvester matrix equations over generalized bisymmetric matrices显示文摘 | Mehdi D Masoud H | | 0，，： | 1 |
| 16 | An efficient algorithm for solving general couplcd matrix equations and its application显示文摘 | Mehdi D Masoud H | | 0，，： | 1 |
| 17 | Two algorithms for finding the Hermitian reflexive and skew-Hermitian solutions of Sylvester matrix equations显示文摘 | Mehdi D Masoud H | | 0，，： | 1 |
| 18 | Green products and corporate strategy: an empirical investigation显示文摘 | Clare D’Souza Mehdi Taghian Peter Lamb Roman Peretiatkos | 2006 | Society and Business Review2006，，： | 1 |
| 19 | Green advertising effects on attitude and choice of advertising themes显示文摘 | Clare D' Souza and Mehdi Taghian | 2005 | Asia Pacific of Market ing and Logistics2005，17，3： | 1 |
| 20 | Application of He's variational iteration method for solving the Cauchy reaction-diffusion problem显示文摘 | MEHDI D FATE S | 2008 | J Compu Appl Math2008，214，2： | 1 |
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