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1Formation mechanism of carbonate cemented zones adjacent to the top overpressured surface in the central Junggar Basin,NW China显示文摘Carbonate cemented zones are normally adjacent to the top overpressured surface in the central Junggar Basin,NW China.Stable carbon and oxygen isotopic compositions and petrological investigations of carbonate cements in the carbonate cemented zones indicate that:(1) carbonate cements are composed dominantly of ferrocalcite,ferroan dolomite,and ankerite;(2) carbonate cements are formed under a high temperature circumstance in the subsurface,and organic fluid migration has an important effect on the formation of them;and(3) carbon and oxygen ions in the carbonate cements migrate from the underlying overpressured system.This suggests that the occurrence of carbonate cemented zones in this region results from multiple phases of organic fluid expulsion out of the overpressure compartment through geological time.This study provides a plausible mechanism of the formation of carbonate cemented zones adjacent to the top overpressured surface in the clastic sedimentary basins,and has an important implication for understanding the internal correlation between the formation of carbonate cemented zones adjacent to top overpressured surface and geofluids expulsion out of overpressured system.YANG Zhi1,2,ZOU CaiNeng1,3,HE Sheng2,LI QiYan1,HE ZhiLiang3,WU HengZhi5,CAO Feng1,MENG XianLong4,WANG FuRong2 & XIAO Qilin21 State Key Laboratory of EOR,Research Institute of Petroleum Exploration & Development,PetroChina,Beijing 100083,China 2 Key Laboratory of Tectonics and Petroleum Resources of Ministry of Education,China University of Geosciences,Wuhan 430074,China 3 State Key Laboratory of EOR,Research Institute of Petroleum Exploration & Development,Petrochina,Beijing 100083,China 4 Research Institute of Petroleum Exploration and Production,SINOPEC,Beijing 100083,China 5 Southwest Branch Company,SINOPEC,Chengdu 610051,China 2010Science China Earth Sciences2010,53,4:12
2Arsenic trioxide promotes mitochondrial DNA mutation and cell apoptosis in primary APL cells and NB4 cell lines显示文摘This study aimed to investigate the effects of arsenic trioxide(As2O3) on the mitochondrial DNA(mtDNA) of acute promyelocytic leukemia(APL) cells.The NB4 cell line was treated with 2.0 μmol/L As2O3 in vitro,and the primary APL cells were treated with 2.0 μmol/L As2O3 in vitro and 0.16 mg kg-1 d-1 As2O3 in vivo.The mitochondrial DNA of all the cells above was amplified by PCR,directly sequenced and analyzed by Sequence Navigatore and Factura software.The apoptosis rates were assayed by flow cytometry.Mitochondrial DNA mutation in the D-loop region was found in NB4 and APL cells before As2O3 use,but the mutation spots were remarkably increased after As2O3 treatment,which was positively correlated to the rates of cellular apoptosis,the correlation coefficient:rNB4-As2O3=0.973818,and rAPL-As2O3=0.934703.The mutation types include transition,transversion,codon insertion or deletion,and the mutation spots in all samples were not constant and regular.It is revealed that As2O3 aggravates mtDNA mutation in the D-loop region of acute promyelocytic leukemia cells both in vitro and in vivo.Mitochondrial DNA might be one of the targets of As2O3 in APL treatment.MENG Ran1,ZHOU Jin2,SUI Meng3,LI ZhiYong4,FENG GuoSheng1 & YANG BaoFeng2 1 Division of Neurology,the Ninth Clinical Medical College of Beijing University(Shijitan Hospital),Beijing 100038,China 2 The First Hospital of Harbin Medical University,Harbin 150001,China 3 Management Information System,University of International Business and Economics,Beijing 100029,China 4 Department of Radiology,Cambridge University Hospitals NHS Foundation Trust Box 219 Level 5,Addenbrooke’s Hospital Cambridge CB2 0QQ,UK 2010Science China(Life Sciences)2010,53,1:10
3Oxidative stress in Dahl salt?sensitive hypertension显示文摘Meng 5 Cason G W Gannon A W 2003Hypertension2003,41,6:1
4Optimization of the imaginary time step evolution for the Dirac equation显示文摘Taking the single neutron levels of 12C in the Fermi sea as examples,the optimization of the imaginary time step(ITS) evolution with the box size and mesh size for the Dirac equation is investigated.For the weakly bound states,in order to reproduce the exact single-particle energies and wave functions,a relatively large box size is required.As long as the exact results can be reproduced,the ITS evolution with a smaller box size converges faster,while for both the weakly and deeply bound states,the ITS evolutions are less sensitive to the mesh size.Moreover,one can find a parabola relationship between the mesh size and the corresponding critical time step,i.e.,the largest time step to guarantee the convergence,which suggests that the ITS evolution with a larger mesh size allows larger critical time step,and thus can converge faster to the exact result.These conclusions are very helpful for optimizing the evolution procedure in the future self-consistent calculations.LI FangQiong1,ZHANG Ying2,LIANG HaoZhao2,3 & MENG Jie4,2,5 1Guizhou University for Nationalities,Guiyang 550025,China 2State Key Lab Nuclear Physics & Technology,School of Physics,Peking University,Beijing 100871,China 3Institut de Physique Nucle’aire,IN2P3-CNRS and Universite’ Paris-Sud,F-91406 Orsay Cedex,France 4School of Physics and Nuclear Energy Engineering,Beihang University,Beijing 100191,China 5Department of Physics,University of Stellenbosch,Stellenbosch,South Africa 2011Science China(Physics,Mechanics & Astronomy)2011,54,2:1
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