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| 1 | 104例老年骨质疏松性骨盆骨折的治疗——骨水泥型经髂骨螺钉内固定系统介绍显示文摘目的探讨骨水泥型经髂骨螺钉内固定系统(TIFI)治疗老年骨质疏松性骨盆骨折的方法。方法回顾性分析2004年1月至2014年11月期间收治的104例年龄≥59岁的骨盆骨折患者资料。男11例,女93例;年龄为59~94岁,平均(77.5±7.6)岁。骨折根据Ptommens分型:I型31例,Ⅱ型39例,Ⅲ型19例,Ⅳ型15例。致伤原因:平地摔伤89例,从低于3m高处摔伤8例,无明确外伤史7例。保守治疗65例;手术治疗39例,其中17例患者采用骨水泥型TIFI固定治疗,将宁心钉和SchalIZ钉从髂后卜棘到髂前下棘置入,并固定于髋臼上方。结果65例保守治疗患者出院当天活动度:坐轮椅1例,平地行走26例,可上下楼8例,未记录30例。39例手术治疗患者出院当天活动度:坐轮椅6例,平地行走26例,可上下楼1例,未记录6例。34例Schanz钉固定患者中,有2例固定髂骨时出现螺钉穿透骶髂关节。16例Schanz钉结合骨水泥固定患者中,未观察到骨水泥溢出至骶髂关节。Schanz钉髂骨置钉深度平均为(100±20)mm,连接杆的长度平均为(62±16)mm。17例采用TIFI固定的患者中,2例术后出现血肿,I例出现浅表伤口感染,未出现深层组织感染或内固定感染。结论老午骨质疏松性骨盆骨折可根据Rommens分型来选择治疗方式。骨水泥型TIFI固定是~一种治疗老年骨质疏松性骨笳骨折的微创、可靠方法。 | Paul Schmitz Stephan Luedeek 王博炜 Rupert Schupfner Michael Worlieek Michael Nerlich Michael Bernhard Muller | 2017 | 中华创伤骨科杂志2017，19，5： | 10 |
| 2 | The evolution of corneal and refractive surgery with the femtosecond laser显示文摘The use of femtosecond lasers has created an evolution in modern corneal and refractive surgery.With accuracy,safety,and repeatability,eye surgeons can utilize the femtosecond laser in almost all anterior refractive procedures;laser in situ keratomileusis(LASIK),small incision lenticule extraction(SMILE),penetrating keratoplasty(PKP),insertion of intracorneal ring segments,anterior and posterior lamellar keratoplasty(Deep anterior lamellar keratoplasty(DALK)and Descemet's stripping endothelial keratoplasty(DSEK)),insertion of corneal inlays and cataract surgery.As the technology matures,it will push surgical limits and open new avenues for ophthalmic intervention in areas not yet explored.As we witness the transition from femto-LASIK to femto-cataract surgery it becomes obvious that this innovation is here to stay.This article presents some of the most relevant advances of femtosecond lasers to modern corneal and refractive surgery. | Antonis Aristeidou Elise V.Taniguchi Michael Tsatsos Rodrigo Muller Colm McAlinden Roberto Pineda Eleftherios I.Paschalis | 2015 | Eye and Vision2015，2，1： | 9 |
| 3 | Decreasing nutrient concentrations in soils and trees with increasing elevation across a treelineecotone in Rolwaling Himal, Nepal显示文摘At a global scale, tree growth in alpine treeline ecotones is limited by low temperatures. At a local scale, however, tree growth at its upper limit depends on multiple interactions of influencing factors and mechanisms. The aim of our research was to understand local scale effects of soil properties and nutrient cycling on tree growth limitation, and their interactions with other abiotic and biotic factors in a near-natural Himalayan treeline ecotone. Soil samples of different soil horizons, litter, decomposition layers, and foliage samples of standing biomass were collected in four altitudinal zones along three slopes, and were analysed for exchangeable cations and nutrient concentrations, respectively. Additionally, soil and air temperature, soil moisture, precipitation, and tree physiognomy patterns were evaluated. Both soil nutrients and foliar macronutrient concentrations of nitrogen(N), magnesium(Mg), potassium(K), and foliar phosphorus(P) decrease significantly with elevation. Foliar manganese(Mn) concentrations, bycontrast, are extraordinarily high at high elevation sites. Potential constraining factors on tree growth were identified using multivariate statistical approaches. We propose that tree growth, treeline position and vegetation composition are affected by nutrient limitation, which in turn, is governed by low soil temperatures and influenced by soil moisture conditions. | Simon DROLLINGER Michael MULLER Timo KOBL Niels SCHWAB Jurgen BOHNER Udo SCHICKHOFF Thomas SCHOLTEN | 2017 | Journal of Mountain Science2017，14，5： | 4 |
| 4 | Implications of tree species–environment relationships for the responsiveness of Himalayan krummholz treelines to climate change显示文摘Climate warming is expected to advance treelines to higher elevations. However, empirical studies in diverse mountain ranges give evidence of both advancing alpine treelines as well as rather insignificant responses. In this context, we aim at investigating the sensitivity and responsiveness of the near-natural treeline ecotone in Rolwaling Himal, Nepal, to climate warming. We analysed population densities of tree species along the treeline ecotone from closed forest stands via the krummholz belt to alpine dwarf shrub heaths(3700-4200 m) at 50 plots in 2013 and 2014. We quantified species-environment relationships, i.e. the change ofenvironmental conditions(e.g., nutrient and thermal deficits, plant interactions) across the ecotone by means of redundancy analyses, variation partitioning and distance-based Moran's eigenvector maps. In particular, we focus on explaining the high competitiveness of Rhododendron campanulatum forming a dense krummholz belt and on the implications for the responsiveness of Himalayan krummholz treelines to climate change. Results indicate that treeline trees in the ecotone show species-specific responses to the influence of environmental parameters, and that juvenile and adult tree responses are modulated by environmental constraints in differing intensity. Moreover, the species-environment relationships suggest that the investigated krummholz belt will largely prevent theupward migration of other tree species and thus constrain the future response of Himalayan krummholz treelines to climate warming. | Niels SCHWAB Udo SCHICKHOFF Birgit BURZLE Michael MULLER Jurgen BOHNER Ram Prasad CHAUDHARY Thomas SCHOLTEN Jens OLDELAND | 2017 | Journal of Mountain Science2017，14，3： | 3 |
| 5 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 6 | Multicenter analysis of soluble A xl reveals diagnostic value for very early stage hepatocellular carcinoma显示文摘 | Patrick Reichl Meng Fang Patrick Starlinger Katharina Staufer Rudolf Nenutil Petr Muller Kristina Greplova Dalibor Valik Steven Dooley Christine Brostjan Thomas Gruenberger Jiayun Shen Kwan Man Michael Trauner Jun Yu Chun Fang Gao Wolfgang Mikulits | 2015 | Int. J. Cancer2015，，2： | 2 |
| 7 | Self-compacting lightweight con- crete-technology and use 显示文摘 | MUller Harald S Haist Michael | 2005 | Betonwerk und Fertigteil-Technik2005，71，2： | 1 |
| 8 | The effects of oxidative stress on the liver sieve显示文摘 | Victoria C Cogger Michael Muller | 2004 | Journal of Hepatology2004，，41： | 1 |
| 9 | Efficient content-based retrieval of motion capture data显示文摘 | Muller Meinard Roder Tido Clausen Michael | 2005 | ACM Transactions on Graphics2005，24，3： | 1 |
| 10 | Thermal investigations of amber and copal显示文摘 | Michael Feist Ingolf Lamprecht Frank MUller | 2007 | Thermochimica Aeta2007，，458： | 1 |
| 11 | Disciplines, skills and the university显示文摘 | Johan Muller Michael Young | 2014 | Higher Education2014，，2： | 1 |
| 12 | PPARs,Obesity,and Inflammation显示文摘 | Rinke Stienstra Caroline Duval Michael Muller | 2007 | PPAR Research2007，2007，10： | 1 |
| 13 | Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels显示文摘 | Michael S. Lustgarten Arunabh Bhattacharya Florian L. Muller Youngmok C. Jang Takahiko Shimizu Takuji Shirasawa Arlan Richardson Holly Van Remmen | 2012 | Biochemical and Biophysical Research Communications2012，，3： | 1 |
| 14 | [20] Analysis of altered gene expression by differential display显示文摘 | Peng Liang David Bauer Lidia Averboukh Peter Warthoe Markus Rohrwild Heiko Muller Michael Strauss Arthur B. Pardee | 1995 | Methods in Enzymology1995，，： | 1 |
| 15 | An ultra-compact particle size analyser using a CMOS image sensor and machine learning显示文摘Light scattering is a fundamental property that can be exploited to create essential devices such as particle analysers.The most common particle size analyser relies on measuring the angle-dependent diffracted light from a sample illuminated by a laser beam.Compared to other non-light-based counterparts,such a laser diffraction scheme offers precision,but it does so at the expense of size,complexity and cost.In this paper,we introduce the concept of a new particle size analyser in a collimated beam configuration using a consumer electronic camera and machine learning.The key novelty is a small form factor angular spatial filter that allows for the collection of light scattered by the particles up to predefined discrete angles.The filter is combined with a light-emitting diode and a complementary metal-oxide-semiconductor image sensor array to acquire angularly resolved scattering images.From these images,a machine learning model predicts the volume median diameter of the particles.To validate the proposed device,glass beads with diameters ranging from 13 to 125μm were measured in suspension at several concentrations.We were able to correct for multiple scattering effects and predict the particle size with mean absolute percentage errors of 5.09% and 2.5% for the cases without and with concentration as an input parameter,respectively.When only spherical particles were analysed,the former error was significantly reduced(0.72%).Given that it is compact(on the order of ten cm)and built with low-cost consumer electronics,the newly designed particle size analyser has significant potential for use outside a standard laboratory,for example,in online and in-line industrial process monitoring. | Rubaiya Hussain Mehmet Alican Noyan Getinet Woyessa Rodrigo R.Retamal Marin Pedro Antonio Martinez Faiz M.Mahdi Vittoria Finazzi Thomas A.Hazlehurst Timothy N.Hunter Tomeu Coll Michael Stintz Frans Muller Georgios Chalkias Valerio Pruneri | 2020 | Light(Science & Applications)2020，9，1： | 1 |
| 16 | Suction dressings to secure a dermal substitute显示文摘 | Winston McEwan Tim La H Brown Stephen M Mills Michael J Muller | 2003 | Burns2003，，： | 1 |
| 17 | Improved Chemometric Strategies for Quantitative FTIR 显示文摘 | Michael Heise H Uwe Muller Andrea G Gartrer | 2001 | Field Analytical Chemistry and Technology2001，5，1： | 1 |
| 18 | Are there endogenous molecules that protect kidneys from injury? The case from bone morphogenic protein-7 (BMP-7) 显示文摘 | MICHAEL Z GERHARD A MULLER | 2004 | Nephrol Dial Transplant2004，19，4： | 1 |
| 19 | New physical model for thermoelectric generator 显示文摘 | Fueunek Michael Muller Nonika Ungan Tolgay | 2009 | J Electronic Materials2009，38，7： | 1 |
| 20 | Engine Mount and NVH显示文摘 | Michael Muller | 1994 | Automotive Engineering1994，，7： | 1 |
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