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| 1 | Lipophilic phenolic antioxidants: Correlation between antioxidant profile, partition coefficients and redox properties显示文摘 | Fernanda M.F. Roleira Christophe Siquet Elizabeta Orrù E. Manuela Garrido Jorge Garrido Nuno Milhazes Gianni Podda Fátima Paiva-Martins Salette Reis Rui A. Carvalho Elisiário J. Tavares da Silva Fernanda Borges | 2010 | Bioorganic & Medicinal Chemistry2010，，16： | 1 |
| 2 | Functional and patient-reported outcomes of bone-anchored hearing aids (BAHA): A prospective case series study显示文摘Objective:The purpose of this study was to evaluate the functional and patient-reported outcomes,and their correlation,after percutaneous bone-anchored hearing aid(BAHA)implantation.Methods:A prospective study was conducted between January 2018 and December 2020 in a tertiary care center.All adult patients who were implanted with a percutaneous BAHA device during this evaluation period were included in the study.Complete auditory function and patients reported outcome measures(PROMs)were assessed in the preoperative period and 6 months after the implant activation.The PROMs included a generic form(Medical Outcome Study 36 Short Form Healthy Survey(MOS SF-36)),and three disease-specific forms(Hearing Handicap Inventory(HHI),Satisfaction with Amplification in Daily Life Scale(SADLS),and Tinnitus Handicap Inventory(THI)).Results:Twenty-two patients with an average age of 53 years were included in the study.The overall functional gain with the BAHA in sound-field pure tone average(PTA)was 29 dB,with no statistically significant differences according to surgical indication(F(3,18)=2.319,p=0.110).The greater the preoperative air-bone gap,the greater the functional gain obtained(r=0.505,p<0.05).In the PROMs,we found a significant improvement in HHI scores(p<0.005)and a significant increase in overall SADLS scores(p<0.05)with the use of percutaneous BAHA devices.We did not verify any statistically significant correlation between functional and PROMs results.Conclusions:The BAHA is a safe and effective alternative hearing rehabilitation option in selected patients.The PROMs results prove patient's overall satisfaction. | Catia Azevedo Miguel Breda Daniela Ribeiro Fernando Milhazes Mar Sergio Vilarinho Luis Dias | 2023 | Journal of Otology2023，18，1： | 1 |
| 3 | β-Nitrostyrene derivatives:a conformational study by combined Raman spectroscopy and ab initio MO calculations显示文摘 | Calheiros R Milhazes N Borges F | 2004 | Journal of Molecular Structure2004，692，： | 1 |
| 4 | β-Nitrostyrene derivatives as potential antibacterial agents:a structure-property-activity relationship study显示文摘 | Milhazes N Calheiros R Marques M P M | 2006 | Bioorganic & Medicinal Chemistry2006，14，： | 1 |
| 5 | Simple coumarins and analogues in medicinal chemistry:occurrence,synthesis and biological activity显示文摘 | Borges F Roleira F Milhazes N | 2005 | Curr Med Chem2005，12，8： | 1 |
| 6 | Vestibular and cochlear dysfunction in aging:Two sides of the same coin?显示文摘Objective:Nonspecific complaints of hearing loss,vertigo,imbalance,and instability,without a defined etiology,are very prevalent in the elderly population,with a great impact on morbidity and mortality in this age group.The objectives of this study were to verify whether there is age-related vestibular dysfunction and to test the association of vestibular dysfunction with presbycusis in the elderly population.Methods:Original retrospective analytical cross-sectional study,carried out with 80 patients who underwent a videonystagmography and complete audiometric evaluation due to nonspecific vestibular complaints,without a specific vestibular disorder diagnosis.Patients were selected and divided into two distinct age groups(group A:>60 years;group B:18-50 years)and,in both groups,we analyzed the caloric tests and the pure-tone audiometry.Results:In the vestibular evaluation,we found that there was a statistically significant difference(P<0.05)between groups in the prevalence of bilateral vestibular weakness(group A:22.5%;group B:5%),and that the increase in age,above 60 years,is negatively correlated with the mean total caloric response.Additionally,we obtained a reasonable negative and statistically significant correlation(r=-0.320,P<0.05)between the mean bone conduction thresholds at high frequencies and total caloric responses in group A.Conclusions:In patients with hearing loss,it is essential to perform a complete vestibular study to diagnose vestibular disorders and,consequently,prevent adverse outcomes that may result from these alterations. | Catia Azevedo Sergio Vilarinho Ana Sousa Menezes Fernando Milhazes Mar Luis Dias | 2022 | World Journal of Otorhinolaryngology-Head and Neck Surgery2022，8，4： | 0 |
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