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| 1 | Metabolic,autonomic and immune markers for cardiovascular disease in posttraumatic stress disorder显示文摘Posttraumatic stress disorder(PTSD) has been associated with significantly greater incidence of heart disease.Numerous studies have indicated that health problems for individuals with PTSD occur earlier in life than in the general population. Multiple mechanistic pathways have been suggested to explain cardiovascular disese(CVD)risk in PTSD,including neurochemical,behavioral,and immunological changes. The present paper is a review of recent research that examines cardiovascular and immune risk profiles of individuals with PTSD. First,we address the relatively new evidence that the constellation of risk factors commonly experienced in PTSD fits the profile of metabolic syndrome. Next we examine the findings concerning hypertension/blood pressure in particular. The literature on sympathetic and parasympathetic responsivity in PTSD is reviewed. Last,we discuss recent findings concerning immune functioning in PTSD that may have a bearing on the high rates of CVD and other illnesses. Our primary goal is to synthesize the existing literature by examining factors that overlap mechanistically to increase the risk of developing CVD in PTSD. | Jeffrey L Kibler Mischa Tursich Mindy Ma Lydia Malcolm Rachel Greenbarg | 2014 | World Journal of Cardiology2014，6，6： | 2 |
| 2 | Structural Characterization and Photocatalytic Activity of Synthesized Carbon Modified TiO2 for Phenol Degradation显示文摘To promote the photocatalytic performance TiO2 and enlarge its application in visible region, carbon doped TiO2 (C/TiO2) composites were synthesized by wet impregnation method using sucrose as a precursor and used for phenol photocatalytic reaction. The synthesized products were characterized by Nitrogen adsorption-desorption isotherms (BET), X-ray diffraction (XRD), transmission electron microscopy (TEM) and UV-visible diffuse reflectance spectroscopy (UV-vis) techniques. The results showed that the obtained TiO2 was anatase phase in the C/TiO2 products, and its crystallite size was 11.7 nm, respectively. Carbon amount and calcined temperature of C/TiO2 can promote phenol removal. In this experiment, 5% carbon and 500 ℃ are the best choice for photocatalyst preparation. Under the UV light irradiation, 5%C/TiO2 (500 ℃, 2 h) exhibited the efficiency of 70.0% for phenol degradation within 150 min whereas TiO2 (500 ℃, 2 h) had 53.0% in the same duration of time. Also 5%C/TiO2 (500 ℃, 2 h) has higher photocatalytic performance under sunlight than pure TiO2. A combination of factors that include the smallest crystalline size, higher anatase percent, less band gap energy value and more oxygen vacant resulted in higher photocatalytic activities of 5%C/TiO2 (500 ℃, 2 h). | 张金源 ZHENG Yanbing MA Mindi 李惠娟 | 2020 | Journal of Wuhan University of Technology(Materials Science)2020，35，3： | 2 |
| 3 | PET imaging on neurofunctional changes after optogenetic stimulation in a rat model of panic disorder显示文摘Panic disorder (PD) is an acute paroxysmal anxiety disorder with poorly understood pathophysiology. The dorsal periaqueductal gray (dPAG) is involved in the genesis of PD. However, the downstream neurofunctional changes of the dPAG during panic attacks have yet to be evaluated in vivo. In this study, optogenetic stimulation to the dPAG was performed to induce panic-like behaviors, and in vivo positron emission tomography (PET) imaging with ,8F-flurodeoxyglucose (18F-FDG) was conducted to evaluate neurofunctional changes before and after the optogenetic stimulation. Compared with the baseline, post-optogenetic stimulation PET imaging demonstrated that the glucose metabolism significantly increased (P < 0.001) in dPAG, the cuneiform nucleus, the cerebellar lobule, the cingulate cortex, the alveus of the hippocampus, the primary visual cortex, the septohypothalamic nucleus, and the retrosplenial granular cortex but significantly decreased (P < 0.001) in the basal ganglia, the frontal cortex, the forceps minor corpus callosum, the primary somatosensory cortex, the primary motor cortex, the secondary visual cortex, and the dorsal lateral geniculate nucleus. Taken together, these data indicated that in vivo PET imaging can successfully detect downstream neurofunctional changes involved in the panic attacks after optogenetic stimulation to the dPAG. | Xiao He Chentao Jin Mindi Ma Rui Zhou Shuang Wu Haoying Huang Yuting Li Qiaozhen Chen Mingrong Zhang Hong Zhang Mei Tian | 2019 | Frontiers of Medicine2019，13，5： | 0 |
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