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| 1 | An Ebola virus-encoded microRNA-like fragment serves as a biomarker for early diagnosis of Ebola virus disease显示文摘 | Zeliang Chen Hongwei Liang Xi Chen Yuehua Ke Zhen Zhou Mingjuan Yang Ke Zen Ruifu Yang Chao Liu Chen-Yu Zhang | 2016 | Cell Research2016，26，3： | 7 |
| 2 | De Novo Design of Polymeric Carrier to Photothermally Release Singlet Oxygen for Hypoxic Tumor Treatment显示文摘Intratumoral hypoxia extremely limits the clinic applications of photodynamic therapy(PDT).Endoperoxides allow thermally releasing singlet oxygen(1O_(2))in a defned quantity and ofer promising opportunities for oxygen-independent PDT treatment of hypoxic tumors.However,previous composite systems by combining endoperoxides with photothermal reagents may result in unpredicted side efects and potential harmful impacts during therapy in vivo.Herein,we de novo design an all-in-one polymer carrier,which can photothermally release 1O_(2).Te strategy has been demonstrated to efectively enhance the production of 1O_(2) and realize the photodamage in vitro,especially in hypoxic environment.Additionally,the polymer carrier accumulates into tumor afer intravenous injection via the enhanced permeation and retention efects and accelerates the oxygen-independent generation of 1O_(2) in tumors.Te oxidative damage results in good inhibitory efect on tumor growth.Realization of the strategy in vivo paves a new way to construct photothermal-triggered oxygen-independent therapeutic platform for clinical applications. | Tianci Huang Menglong Zhao Qi Yu Zheng Feng Mingjuan Xie Shujuan Liu Kenneth Yin Zhang Qiang Zhao Wei Huang | 2019 | Research2019，，1： | 6 |
| 3 | 螺旋CT与超声造影在肾细胞癌诊断中的对比研究(英文)显示文摘Objective: To investigate the efficiency of helical CT comparing with contrast-enhanced ultrasound, and to im- prove the diagnosis efficiency of renal cell carcinoma (RCC). Methods: Thirty RCCs confirmed pathologically were studied retrospectively. The un-enhanced CT scan and the triphasic enhanced helical CT scan were performed in all cases, the gray-scale US and angiosonography with SonoVue were performed in all cases meantime. Results: 22 cases (73.3%) were diagnosed correctly by helical CT alone before operation. 7 cases (23.3%) were suspected as RCC with helical CT. One case (3.3%) was misdiagnosed with helical CT. 25 cases (83.3%) were diagnosed correctly with contrast-enhanced ultrasound alone pre-operation. One case (3.3%) was suspected as RCC with angiosonography. Four cases (13.3%) were misdiagnosed with angiosonography alone. 29 cases (96.7%) were diagnosed correctly by helical CT combining with angiosonography before operation, one case (3.3%) was diagnosed as renal mass with both helical CT and angiosonography. Conclusion: Contrast-enhanced ultrasound is sensitive in detecting blood flow, it can detect the enhancement of the tumor which cannot be detected by helical CT. CT and angiosonography have strong complement each other in the diagnosis of RCC. | Yan Guo Guangsheng Wan Yaqing Chen Mingjuan Liu Qian Peng Zhaomin Huang | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，2： | 1 |
| 4 | Isolation and functional characterization of the JcERF gene, a putative AP2/ EREBP domain containing transcription factor, in the woody oil plant Jatropha curcas 显示文摘 | Mingjuan Tang Jingwen Sun Yun Liu | 2007 | Plant Mol Biol2007，63，： | 1 |
| 5 | Preoperative versus intraoperative endoscopic sphincterotomy in patients with gallbladder and suspected common bile duct stones: system review and meta-analysis显示文摘 | Bin Wang Zhenying Guo Zhenjie Liu Yuan Wang Yi Si Yuefeng Zhu Mingjuan Jin | 2013 | Surgical Endoscopy2013，，7： | 1 |
| 6 | Dynamic effective elastic modulus of polymer matrix composites with dense piezoelectric nano-fibers considering surface/interface effect显示文摘Based on effective field method,the dynamic effective elastic modulus of polymer matrix composites embedded with dense piezoelectric nano-fibers is obtained,and the interacting effect of piezoelectric surfaces/interfaces around the nano-fibers is considered.The multiple scattering effects of harmonic anti-plane shear waves between the piezoelectric nano-fibers with surface/interface are averaged by effective field method.To analyze the interacting results among the random nano-fibers,the problem of two typical piezoelectric nano-fibers is introduced by employing the addition theorem of Bessel functions.Through numerical calculations,the influence of the distance between the randomly distributed piezoelectric nano-fibers under different surface/interface parameters is analyzed.The effect of piezoelectric property of surface/interface on the effective shear modulus under different volume fractions is also examined.Comparison with the simplified cases is given to validate this dynamic electro-elastic model. | FANG XueQian HUANG MingJuan ZHU ZiTao LIU JinXi FENG WenJie | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，1： | 1 |
| 7 | 血供丰富的乏脂肪肾脏错构瘤与肾透明细胞癌的CT鉴别诊断(英文)显示文摘Objective: The aim of our study was to investigate the feature of minimal fat renal angiomyolipoma with sufficient blood supply using CT scans and improve the diagnosis accuracy required to differentiate it from clear cell renal carcinoma.Methods: Retrospective analysis of 24 cases of post-surgery confirmed angiomyolipoma with sufficient blood supply (total of 25 tumors) in our hospital that were used for a pathological comparison study.Results: Among the 24 patients diagnosed with angiomyolipoma,nobody had bloody urine.Of the 96 patients diagnosed with clear cell renal cancer,14 had bloody urine (14.6%).In our studied group,the size of angiomyolipomas with sufficient blood supply was between 1.5 cm × 2.0 cm to 8.0 cm × 10.0 cm.During CT scan analysis,twenty tumors had similar density,and five of them had higher density.Only one tumor had a few dots of calcification (4%).Adipose tissue was not visible in 9 tumors,while 16 tumors had visible dots of adipose tissue,as visualized by CT scan.Intensive scanning indicated that all of the tumors showed a strong enhancement in the renal corticomedullary phase.Twenty tumors had significant heterogeneous enhancement in the early phase,while another set of five cases had homogenous prolonged enhancement.Nineteen patients had surgery to remove the angiomyolipomas,while six patients had single side kidney removal due to misdiagnosis for renal cancer in cases where the tumor severely compromised the renal parenchyma and sinus.All 25 cases were classified as renal angiomyolipoma by pathological analysis.Within the 96 cases of clear cell renal cancer,64 tumors had relatively low density,29 tumors had equal density,and 3 cases had relatively higher density.Fourteen of the tumors had calcification (14.6%),and none of them had visualized adipose tissue.Enhanced CT scans indicated that 69 cases of renal cancer showed significant enhancement in the renal corticomedullary phase,which had the abnormal pattern of 'fast-in-and-fast-out'.Additionally,27 cases had slow and prolonged enhancement.Conclusion: Similar to clear cell renal carcinomas,angiomyolipomas with sufficient blood supply also appear to exhibit abnormal enhancement with a pattern of 'fast-in-and-fast-out' during the early phase,which is easily misdiagnosed as renal cancer.It is difficult to differentiate them merely through CT scans;the key to differentiating them is to identify the adipose tissue within the tumor.Therefore,it is helpful to use thin-layer CT scans to locate the adipose tissue. | Yan Guo Qian Peng Zhuo Wang Mingjuan Liu Xufeng Yang Teng Long | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，1： | 1 |
| 8 | A NEW SINGULARITY EXTRACTION TECHNIQUE FOR TDEFIE显示文摘A new singularity extraction technique is presented to calculate accurately the singular integrals in Time Domain Electric Field Integral Equation (TDEFIE).In singularity extraction pro- cedure,through the aid of the first order Taylor series of time base function including time-retardation,the singularity of the integrand can be removed.The surface current density and backscattered far-field response of a conducting cube illuminated by a Gaussian plane wave is com- puted using the presented technique.Comparisons are made with the results obtained by the Inverse Discrete Fourier Transform (IDFT) of the frequency domain and the results obtained by using Ve- chinski's time averaging technique,which demonstrate that the presented method with this new time domain singularity extraction technique to solve TDEFIE is very accurate and stable. | Liu Feng Zhou Dongming Cai Mingjuan Ren Meng He 3iangguo | 2007 | Journal of Electronics(China)2007，24，5： | 1 |
| 9 | Genetic polymorphisms of transforming growth factor-β1 and its receptors and colorectal cancer susceptibility: A population-based case-control study in China显示文摘 | Yongjing Zhang Bing Liu Mingjuan Jin Qin Ni Xia Liang Xinyuan Ma Kaiyan Yao Qilong Li Kun Chen | 2008 | Cancer Letters2008，，： | 1 |
| 10 | Attenuation mechanism of Brucella melitensis M5-10,implications for vaccine development and differential diagnosis显示文摘Brucellosis is a worldwide zoonosis.Vaccination is the most efficient means to prevent and control brucellosis.The current licensed attenuated vaccines for animal use were developed by sequential passage in nonnatural hosts that decreased virulence in its original hosts.The attenuation mechanism of these strains remains largely unknown.In the present study,we sequenced the genome of Brucella melitensis vaccine strain M5-10.Sequence analysis showed that a large number of genetic changes occurred in the vaccine strains.A total of 2854 genetic polymorphic sites,including 2548 SNP,241 INDEL and 65 MNV were identified.Of the 2074 SNPs in coding regions,1310(63.2%)were non-synonymous SNPs.Gene number,percent and N/S ratios were disproportionally distributed among the cog categories.Genetic polymorphic sites were identified in genes of the virB operon,flagella synthesis,and virulence regulating systems.These data indicate that changes in some cog categories and virulence genes might result in the attenuation.These attenuation mechanisms also have implications for screening and development of new vaccine strains.The genetic changes in the genome represent candidate sites for differential diagnosis between these vaccine strains and other virulence ones.Transcription analysis of virulence genes showed that expression of dnaK,vjbR were reduced in M5-10 strain when compared with that in 16M.A duplex PCR targeting virB6 and dnaK was successfully used to differentiate between M5-10 and the virulent 16M strain.The genome re-sequencing technique represents a strong strategy not only for evaluation of vaccines,but also for development of new vaccines. | Yuanqiang ZHENG Yanchun SHI Chang AN Ruisheng LI Dongjun LIU Yuehua KE Kairong MAO Mingjuan YANG Zeliang CHEN Shorgan BOU | 2014 | Frontiers of Agricultural Science and Engineering2014，1，4： | 0 |
| 11 | Effect of drying-wetting cycles on pore characteristics and mechanical properties of enzyme-induced carbonate precipitation-reinforced sea sand显示文摘Enzyme-induced carbonate precipitation(EICP)is an emanating,eco-friendly and potentially sound technique that has presented promise in various geotechnical applications.However,the durability and microscopic characteristics of EICP-treated specimens against the impact of drying-wetting(D-W)cycles is under-explored yet.This study investigates the evolution of mechanical behavior and pore charac-teristics of EICP-treated sea sand subjected to D-W cycles.The uniaxial compressive strength(UCS)tests,synchrotron radiation micro-computed tomography(micro-CT),and three-dimensional(3D)recon-struction of CT images were performed to study the multiscale evolution characteristics of EICP-reinforced sea sand under the effect of D-W cycles.The potential correlations between microstructure characteristics and macro-mechanical property deterioration were investigated using gray relational analysis(GRA).Results showed that the UCS of EICP-treated specimens decreases by 63.7% after 15 D-W cycles.The proportion of mesopores gradually decreases whereas the proportion of macropores in-creases due to the exfoliated calcium carbonate with increasing number of D-W cycles.The micro-structure in EICP-reinforced sea sand was gradually disintegrated,resulting in increasing pore size and development of pore shape from ellipsoidal to columnar and branched.The gray relational degree suggested that the weight loss rate and UCS deterioration were attributed to the development of branched pores with a size of 100-1000 m m under the action of D-W cycles.Overall,the results in this study provide a useful guidancee for the long-term stability and evolution characteristics of EICP-reinforced sea sand under D-W weathering conditions. | Ming Huang Kai Xu Zijian Liu Chaoshui Xu Mingjuan Cui | 2024 | Journal of Rock Mechanics and Geotechnical Engineering2024，16，1： | 0 |
| 12 | Synthesis and Electrochemical Properties of a Novel Poly(ether sulfone) with Oligoaniline Pendants显示文摘 | LI Fangfei WANG Jiayu ZHOU Mingjuan LIU Xincai WANG Ce CHAO Danming | 2015 | Chemical Research in Chinese Universities2015，31，6： | 0 |
| 13 | Hydrogen Bonding Assembled 3D Supramolecular Structures Formed by 5-Amino-2,4,6-triiodoisophthalic Acid and TV-Heterocyclic Aromatic Ligands显示文摘Three salts constructed by 5-amino-2,4,6-triiodoisophthalic acid(ATIPA) with N-heterocycles aromatic coformers such as pyridine tetrazolium, tetramethylpyraziiie and cyanuric acid were synthesized by slowing evaporation of solvent. X-Ray single crystal analysis shows that hydrogen protons of the carboxyl groups transfer to nitrogen atoms of the N-heterocyclic coformers to form N-H…0 hydrogen bonds in all the three compounds. A huge amount of H-bonds play significant role in tlie construction of these compounds and all of them generate 3D structures through strong O-H…N, O-H…O, N-H…O and weak C-H…O hydrogen bonds. Moreover, solvent water molecules are indispensable in the formation of compounds 1 and 3, which constitutes different supramolecular synthons to bridge individual molecules and chains to form stable structures. In addition, these crystal structures were further characterized by themiogravimetric analysis and infrared spectroscopy. | YU Wenli ZHANG Mingjuan LIU Kang YANG Yu WANG Lei | 2019 | Chemical Research in Chinese Universities2019，35，5： | 0 |
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