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您的检索式：作者名="Mingjun Qiu"
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| 1 | miR-183 inhibits the metastasis of osteosarcoma via downregulation ofthe expression of Ezrin in F5M2 cells显示文摘 | Haien Zhao Mingjun Guo Guangyi Zhao Qiong Ma Baoan Ma Xiuchun Qiu Qingyu Fan | 2012 | International Journal of Molecular Medicine2012，，5： | 1 |
| 2 | A SLC31A1-MEK-DNMT1-miR-124 feedback loop contributes to pancreatic cancer progression显示文摘Although the role of copper (Cu) in promoting KRas- or BRaf-mutation driven cancers via activating MEK1/2 kinases is known, the mechanism by which the copper transporter SLC31A1 (CTR1) is upregulated in pancreatic cancer (PDAC, KRas mutation) is not defined. In this study, we provide evidence that MEK signal maintains a high level of SLC31A1 through silencing the expression of miR-124-3P (miR-124) via a novel MEK-DNMT1-miR-124 feedback loop in PDAC cells. Further, we reveal that miR-124 directly targets suppression of SLC31A1, and miR-124 introduction together with tetrathiomolybdate (TM) treatment hampered pancreatic cancer growth in vitro and in vivo. Our results demonstrate that a SLC31A1-MEK-DNMT1-miR-124 feedback loop is an important pathway to maintain copper absorption and promote pancreatic cancer progression, and we hope to provide a Cu-chelation as an adjuvant treatment strategy, to block the progression in Kras mutant PDAC patients. | Jing Jin Mingjun Ma Bingru Yan Botao Qiu Shounan Lu Lin Yang Yuzhe Nie Sheng Tai Ze Yu Chun-Bo Teng | 2023 | Genes & Diseases2023，10，3： | 0 |
| 3 | Inter-Museum Collaboration Mechanisms and Approaches--A Case Study of Longquan Museum's Partnership with Other Museums显示文摘Longquan Museum in Zhejiang province has capitalized on its unique cultural asset of Longquan Celadon to promote inter-museum collaboration.It has so far established partnership with the Palace Museum in Beijing,the Song Porcelain Museum in Sichuan,the Maritime Silk Road Museum in Guangdong,Zhejiang Provincial Museum,Fudan University,China National Silk Museum,and Beijing Art Museum. | Qiu Xiaoxiang Ji Xiaoyan Wu Mingjun | 2022 | China & The World Cultural Exchange2022，88，6： | 0 |
| 4 | Temperature-mediated structural evolution of vapor–phase deposited cyclosiloxane polymer thin films for enhanced mechanical properties and thermal conductivity显示文摘Polymer-derived ceramic(PDC) thin films are promising wear-resistant coatings for protecting metals and carbon-carbon composites from corrosion and oxidation.However,the high pyrolysis temperature hinders the applications on substrate materials with low melting points.We report a new synthesis route for PDC coatings using initiated chemical vapor deposited poly(1,3,5-trivinyl-1,3,5-trimethylcyclotrisiloxane)(pV_3D_3) as the precurs or.We investigated the changes in siloxane moieties and the network topology,and proposed a three-stage mechanism for the thermal annealing process.The rise of the connectivity number for the structures obtained at increased annealing temperatures was found with strong correlation to the enhanced mechanical properties and thermal conductivity.Our PDC films obtained via annealing at 850℃ exhibit at least 14.6% higher hardness than prior reports for PDCs synthesized below 1100℃.Furthermore,thermal conductivity up to 1.02 W(mK)^(-1) was achieved at the annealing temperature as low as 700℃,which is on the same order of magnitude as PDCs obtained above 1100℃.Using minimum thermal conductivity models,we found that the thermal transport is dominated by diffusons in the films below the percolation of rigidity,while ultra-short mean-free path phonons contribute to the thermal conductivity of the films above the percolation threshold.The findings of this work provide new insights for the development of wear-resistant and thermally conductive PDC thin films for durable protection coatings. | Weiwei Du Jing Tu Mingjun Qiu Shangyu Zhou Yingwu Luo Wee-Liat Ong Junjie Zhao | 2023 | International Journal of Extreme Manufacturing2023，5，2： | 0 |
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