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| 1 | Burden of Clostridium difficile infection between 2010 and 2013:Trends and outcomes from an academic center in Eastern Europe显示文摘AIM:To analyze the incidence and possible risk factors in hospitalized patients treated with Clostridium difficile infection(CDI).METHODS:A total of 11751 patients were admitted to our clinic between 1 January 2010 and 1 May2013.Two hundred and forty-seven inpatients were prospectively diagnosed with CDI.For the risk analysis a 1:3 matching was used.Data of 732 patients matched for age,sex,and inpatient care period and unit were compared to those of the CDI population.Inpatient records were collected from an electronic hospital database and comprehensively reviewed.RESULTS:Incidence of CDI was 21.0/1000 admissions(2.1%of all-cause hospitalizations and 4.45%of total inpatient days).The incidence of severe CDI was 12.6%(2.63/1000 of all-cause hospitalizations).Distribution of CDI cases was different according to the unit type,with highest incidence rates in hematology,gastroenterology and nephrology units(32.9,25 and24.6/1000 admissions,respectively) and lowest rates in 1.4%(33/2312) in endocrinology and general internal medicine(14.2 and 16.9/1000 admissions)units.Recurrence of CDI was 11.3%within 12 wk after discharge.Duration of hospital stay was longer in patients with CDI compared to controls(17.6 ± 10.8d vs 12.4 ± 7.71 d).CDI accounted for 6.3%of allinpatient deaths,and 30-d mortality rate was 21.9%(54/247 cases).Risk factors for CDI were antibiotic therapy[including third-generation cephalosporins or fluoroquinolones,odds ratio(OR) = 4.559;P < 0.001],use of proton pump inhibitors(OR = 2.082,P< 0.001),previous hospitaiization within 12 mo(OR = 3.167,P < 0.001),previous CDI(OR = 15.32;P < 0.001),while presence of diabetes mellitus was associated with a decreased risk for CDI(OR = 0.484;P< 0.001).Treatment of recurrent cases was significantly different from primary infections with more frequent use of vancomycin alone or in combination(P < 0.001),and antibiotic therapy duration was longer(P < 0.02).Severity,mortality and outcome of primary infections and relapsing cases did not significantly differ.CONCLUSION:CDI was accounted for significant burden with longer hospitaiization and adverse outcomes.Antibiotic,PPI therapy and previous hospitaiization or CDI were risk factors for CDI. | Zsuzsanna Kurti Barbara D Lovasz Michael D Mandel Zoltan Csima Petra A Golovics Bence D Csako Anna Mohas Lorant Gnczi Krisztina B Gecse Lajos S Kiss Miklos Szathmari Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，21： | 6 |
| 2 | 氟化处理对植入材料Mg-Ca二元合金腐蚀行为的影响(英文)显示文摘在室温下,将Mg-0.5Ca合金在不同浓度的氢氧化钠和HF溶液浸渍不同的时间,研究HF处理对合金腐蚀行为的影响。采用原子力显微镜、X射线衍射、场发射扫描电子显微镜表征样品的微观组织变化。通过动电位极化和Kokubo溶液浸泡试验测试样品的耐腐蚀性。结果表明,与35%HF处理的样品相比,经40%HF溶液处理的Mg-0.5Ca合金具有更均匀、更致密、更薄的涂层(12.6μm)。电化学测试表明,在Kokubo溶液中,经氟化物处理的Mg-0.5Ca合金样品的耐腐蚀性比未处理样品的高35倍;前者的体外降解速率远远低于后者的。在40%HF溶液处理过的样品表面只出现了一些腐蚀点,而未经处理的样品完全被腐蚀产物覆盖且出现了分层现象。40%HF处理的Mg-0.5Ca合金,具有低的降解速率和良好的生物相容性,是一种有潜力的植入材料。 | Hamid Reza Bakhsheshi-Rad Mohd Hasbullah Idris Moha mmed Rafiq Abdul Kadir Mohammadreza Daroonparvar | 2013 | Transactions of Nonferrous Metals Society of China2013，23，3： | 3 |
| 3 | Tobacco Transplants part 3 :Effect of clipping and undercuttingon yield, value, chemistry and growth显示文摘 | SUGGS C W MOHA PATRA S C JOHNSON W H | 1998 | Tob Sci1998，，47： | 1 |
| 4 | Retroinverso analogs of spadin display increased antidepressant effects 显示文摘 | Veyssiere J Moha Ou Maati H Mazella J | 2015 | Psychopharma- cology (Berl)2015，232，3： | 1 |
| 5 | Antihyper- glycemic Effect of Orthosiphon Stamineus Benth Leaves Ex-tract and Its Bioassay-Guided Fractions 显示文摘 | Moha ned E A H Mohamed A J Asmawi M | 2011 | Molecules2011，16，5： | 1 |
| 6 | Additive value of immunoassay-measured fibrinogen and high - sensitivity creactive protein lev-els for predicting incident cardiovascular events显示文摘 | MOHA S RIFAI N RIDKER P M | 2006 | Circulation2006，114，： | 1 |
| 7 | In-line sorting of irregular potatoes by using automated computer-based machine vision system 显示文摘 | Gamal ElMasry Sergio Cubero Enrique Moha | 2012 | Journal of Food Engineering2012，112，： | 1 |
| 8 | Adaptive Kalman filtering for INS/GPS 显示文摘 | Mohaed H Schwarz K P | 1999 | Journal of Geodesy1999，73，4： | 1 |
| 9 | Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation:a key role for I(Ks)显示文摘 | Ducroq J Moha ou Maati H Guilbot | 2010 | British Journal of Pharmacology2010，159，1： | 1 |
| 10 | Heavy metal pollution: source impact and remedies 显示文摘 | Moha Tnmed A S Kapri A Goel R | 2011 | Environmental Pollution2011，20，： | 1 |
| 11 | One-step iterative process for a finite family of multivalu, ed mappings显示文摘 | Moha Esla All Abkar | 2011 | Math and Comp Mode2011，54，： | 1 |
| 12 | Chemical composition of the seed oil of Zanthoxylum alatum Roxb 显示文摘 | Moha R Velassco N | 1998 | Journal of Essential Oil Research1998，10，20： | 1 |
| 13 | Decor:A method for the specification and detection of code and design smells显示文摘 | Moha N Guhneuc Y G | 2010 | Software Engineer2010，36，1： | 1 |
| 14 | Serum total LDH activity and LDH-2 isozyme in nephrotie syndrome 显示文摘 | Mohas M Szigeti N Marko L | 2008 | Kidney Blood Press Res2008，31，1： | 1 |
| 15 | History and future of food irradiation显示文摘 | JO’ZSEF FARKAS CSILLA MOHA'CSI-FARKAS | 2011 | Trends in Food Science&Technology2011，22，： | 1 |
| 16 | Novel anticarcinogenic activity of an organosulfide from Garlic: inhibition of H-ras oncogene transformed tummer growth in vivo by dissulfide is associated with inhibition of p21ras processing显示文摘 | Mohas RR Agrral R | 1996 | Biochem Biophys Res Commu1996，225，2： | 1 |
| 17 | Haplotype analysis of the apolipoprotein a5 gene in patients with the metabolic syndrome显示文摘 | Kisfali P Mohas M Maasz A | | 0，，07： | 1 |
| 18 | Retinol- binding protein- 4: a possible role in cardiovascular complications 显示文摘 | Moha pa tra J Sharma M Acharya A | 2011 | Br J Pharrnacol2011，164，8： | 1 |
| 19 | Grazing induced biodiversity in the highland ecozone of East Africa 显示文摘 | Woldu Z Mohaed Saleem M A | 2000 | Agriculture Ecosystems and Environment2000，79，1： | 1 |
| 20 | Novel antiearcinogenic activity of an organosulfide from Garlic: inhibition of H-ras oncogene transformed tummer growth in vivo by dissulfide is associated with inhibition of p21ras procession显示文摘 | Mohas RR Agrral R | 1996 | Biochem Biophys Res Commu1996，225，： | 1 |
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