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| 1 | Effect of alternative antibiotics in treatment of cefotaxime resistant spontaneous bacterial peritonitis显示文摘AIM:To evaluate effective alternative antibiotics in treatment of cefotaxime-resistant spontaneous bacterial peritonitis.METHODS:One hundred cirrhotic patients with spontaneous bacterial peritonitis [ascitic fluid polymorphonuclear cell count(PMNLs) ≥ 250 cells/mm 3 at admission] were empirically treated with cefotaxime sodium 2 g/12 h and volume expansion by intravenous human albumin.All patients were subjected to history taking,complete examination,laboratory tests(including a complete blood cell count,prothrombin time,biochemical tests of liver and kidney function,and fresh urine sediment),chest X-ray,a diagnostic abdominal paracentesis,and the sample subjected to total and differential cell count,chemical examination,aerobic and anaerobic cultures.Patients were divided after 2 d by a second ascitic PMNL count into group Ⅰ;patients sensitive to cefotaxime(n = 81),group Ⅱ(n = 19);cases resistant to cefotaxime(less than 25% decrease in ascitic PMNL count).Patients of group Ⅱ were randomly assigned into meropenem(n = 11) or levofloxacin(n = 8) subgroups.All patients performed an end of treatment ascitic PMNL count.Patients were considered improved when:PMNLs decreased to < 250 cells/mm 3,no growth in previously positive culture cases,and improved clinical manifestations with at least 5 d of antibiotic therapy.RESULTS:Age,sex,and Child classes showed no significant difference between group Ⅰ and group Ⅱ.Fever and abdominal pain were the most frequent manifestations and were reported in 82.7% and 80.2% of patients in group Ⅰ and in 94.7% and 84.2% of patients in group Ⅱ,respectively.Patients in group Ⅱ had a more severe ascitic inflammatory response than group Ⅰ and this was demonstrated by more ascitic lactate dehydrogenase(LDH) [median:540 IU/L(range:150-1200 IU/L) vs median:240 IU/L(range:180-500 IU/L),P = 0.000] and PMNL [median:15 000 cell/mm 3(range:957-23 822 cell/mm 3) vs 3400 cell/mm 3(range:695-26 400 cell/mm 3),P = 0.000] counts.Ascitic fluid culture was positive in 32% of cases.Cefotaxime failed in 19% of patients;of these patients,11(100%) responded to meropenem and 6(75%) responded to levofloxacin.Two patients with failed levofloxacin therapy were treated according to the in vitro culture and sensitivity(one case was treated with vancomycin and one case was treated with ampicillin/sulbactam).In group Ⅱ the meropenem subgroup had higher LDH(range:108-860 IU/L vs 120-491 IU/L,P = 0.042) and PMNL counts(range:957-23 822 cell/mm 3 vs 957-15 222 cell/mm 3,P = 0.000) at initiation of the alternative antibiotic therapy;there was no significant difference in the studied parameters between patients responsive to meropenem and patients responsive to levofloxacin at the end of therapy(mean ± SD:316.01 ± 104.03PMNLs/mm 3 vs 265.63 ± 69.61 PMNLs/mm 3,P = 0.307).The isolated organisms found in group Ⅱ were;enterococci,acinetobacter,expanded-spectrum β-lactamase producing Escherichia coli,β-lactamase producing Enterobacter and Staphylococcus aureus.CONCLUSION:Empirical treatment with cefotaxime is effective in 81% of cases;meropenem is effective in cefotaxime-resistant cases. | Ahmed Abouelkhair Badawy Tarik Ibrahim Zaher Samar Mahmoud Sharaf Mohamed Hassan Emara Noha Elsaid Shaheen Talaat Fathy Aly | 2013 | World Journal of Gastroenterology2013，19，8： | 13 |
| 2 | Serum autoantibodies positivity prevalence in patients with chronic HCV and impact on pegylated interferon and ribavirin treatment response显示文摘 | Marwa Khairy Maissa El‐Raziky Wafaa El‐Akel Mohamed S. Abdelbary Hany Khatab Badawy El‐Kholy Gamal Esmat Mahassen Mabrouk | 2013 | Liver Int2013，，10： | 2 |
| 3 | Chitosan as antimicrobial agent : Applications and mode of action 显示文摘 | Entsar I Rabea Mohamed E T Badawy | 2003 | Biomacromolecules2003，，6： | 1 |
| 4 | Extracorporeal shock wave lithotripsy as first line treatment for urinary tract stones in children: outcome of 500 cases显示文摘 | Abdelbasset Badawy Mohamed Saleem Ahmad Abolyosr Mohamed Aldahshoury Mohamed Elbadry Medhat Abdalla Abdelmoneim Abuzeid | 2012 | International Urology and Nephrology2012，，： | 1 |
| 5 | Identification and Quantification of 5-Hydroxymethyl Furfural HMF in Some Sugar-Containing Food Prod-ucts by HPLC显示文摘 | SUZAN ZEIN ALABDEEN MAKAWI MOHAMMED IDREES TAHA BADAWI AHMED ZAKARIA | 2009 | Pakistan Journal of Nutrition2009，8，9： | 1 |
| 6 | The role of the tumor necrosis factor (TNF) – Fas L and HCV in the development of hepatocellular carcinoma显示文摘 | Ola Nada Mohamed Abdel-Hamid Alaa Ismail Laila El Shabrawy Karima F.S. Sidhom Nafissa M.A. El Badawy Faten A.A. Ghazal Mai El Daly Sherif El Kafrawy Gamal Esmat Christopher A. Loffredo | 2005 | Journal of Clinical Virology2005，，2： | 1 |
| 7 | Chitosan as Antimicrobial Agent: Applications and Mode of Action 显示文摘 | Entsar I Rabea Mohamed E T Badawy Christian V Stevens | 2007 | Biomacromolecules2007，6，1： | 1 |
| 8 | Chitosan as antimicrobial agent: Applications and mode of action显示文摘 | Entsar I Rabea Mohamed E T Badawy Christian V Stevens | 2003 | Biomacromolecules2003，4，6： | 1 |
| 9 | Synthesis and fungicidal activity of new N,O-aeyl chitosan derivatives显示文摘 | Mohamed E I Badawy Entsar I Rabea Tina M Rogge | 2004 | Biomacromolecules2004，5，： | 1 |
| 10 | Structure and antirnicrobial activityrelationship of quaternary N-alkyl chitosan derivatives against some plant pathogens显示文摘 | Mohamed E I Badawy | 2010 | Journal of Applied Polymer Science2010，117，： | 1 |
| 11 | Synthesis,Characterization and Biological Activity of Bis(pheny- limine) Schiff Base Ligands and Their Metal Complexes 显示文摘 | MOHAMED G G BADAWY M A OMAR M M | 2006 | Spectrochim Acta Part A2006，64，： | 1 |
| 12 | Chitosan as antimicrobial agent applications and mode of action显示文摘 | Entsar I Rabea Mohamed E T Badawy Christian V Stevens | 2003 | Biomacromolecules2003，6，： | 1 |
| 13 | Synthesis and fungicidal activity of new N, O-acyl ehitosan derivatives显示文摘 | Mohamed E I Badawy Entsar 1 Rabea Tina M Rogge | 2004 | Biomacromolecules2004，5，： | 1 |
| 14 | Structure and antimicrobial activityrelationship of quaternary N-Alkyl Chitosan derivatives againstsome plant pathogens显示文摘 | Mohamed E I Badawy | 2010 | Journal of Applied polymer Science2010，117，： | 1 |
| 15 | Clomiphene citrate or aromatase inhibitors for superovulation in women with unexplained infertility undergoing intrauterine insemination: a prospective randomized trial显示文摘 | Ahmed Badawy Abubaker Elnashar Mohamed Totongy | 2009 | Fertility and Sterility2009，，4： | 1 |
| 16 | Changes in corneal biomechanics and intraocular pressure following Femto-LASIK using Goldman applanation tonometry and ocular response analyzer显示文摘AIM:To compare intraocular pressure(IOP)measurements before and after laser in situ keratomileusis(LASIK)with a femtosecond laser for flap creation using ocular response analyzer(ORA)and Goldmann applanation tonometry,and to identify factors that may influence the preoperative and postoperative IOP.METHODS:A prospective study conducted on myopic patients who underwent LASIK using a femtosecond laser for flap fashioning.Enrolled patients were evaluated preoperatively,6 wk and 3 mo postoperatively for manifest refraction(MR),keratometric(K)readings and central corneal thickness(CCT)using a scheimpflug-based topography.Corneal resistance factor(CRF),corneal hysteresis(CH),Goldmann correlated IOP(IOPg)and corneal compensated IOP(IOPcc)were measured using ORA besides IOP assessment by Goldman applanation tonometry(GAT).RESULTS:There was a statistically significant decrease in measures of IOPg by 3.35±0.83 mm Hg,followed by GAT which decreased by 2.2±0.44 mm Hg,and the least affected by operation was IOPcc which decreased only by 0.87±0.1 mm Hg after 6 wk.After 3 mo follow up there was a statistically significant decrease in IOPcc which decreased only by 0.76±0.4 mm Hg,followed by IOP GAT by 1.6±0.5 mm Hg,and the most affected by operation was IOPg which decreased by 2.3±0.3 mm Hg.Correspondingly,there was a statistically significant decrease in CH and CRF after 6 wk and 3 mo.At 3 mo,the preoperative MR and preoperative GAT were prominent significant predictors of the postoperative GAT changes.The prediction equation was subsumed.CONCLUSION:IOP measurements and corneal biomechanical factors reduce significantly after LASIK with a femtosecond laser for flap creation.The IOPcc values are less influenced by changes in corneal properties than IOPg and GAT,indicating that IOPcc may provide the most reliable measurement of IOP after this procedure. | Ahmed Yassin Hemida Omar M Said Asser A.E.Abdel-Meguid Mohammed Iqbal Amani E Badawi | 2020 | International Journal of Ophthalmology(English edition)2020，13，5： | 1 |
| 17 | A Biopolymer Chitosan and Its Derivatives as Promising Antimicrobial Agents against Plant Pathogens and Their Applications in Crop Protection显示文摘 | Mohamed E. I. Badawy Entsar I. Rabea Bruno Sarmento | 2011 | International Journal of Carbohydrate Chemistry2011，，： | 1 |
| 18 | Chitosan as antimicrobial agent applications and mode of action显示文摘 | Rabea Entsar I Badawy Mohamed E T Stevens Christian V | 2003 | Biomacromolecules2003，6，： | 1 |
| 19 | Identification and quantification of 5-hydroxymcthyl furfural HMF in some sugar-containing food products by HPLC显示文摘 | SUZAN ZEIN ALABDEEN MAKAWI MOHAMMED IDREES TAHA BADAWI AHMED ZAKARIA | 2009 | Pakistan Journal of Nutrition2009，8，9： | 1 |
| 20 | The CBF gene family in hexaploid wheat and its relationship to the phylogenetic complexity of cereal CBFs显示文摘 | Mohamed Badawi Jean Danyluk Barbara Boucho Mario Houde Fathey Sarhan | 2007 | Molecular Genetics and Genomics2007，，5： | 1 |
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