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| 1 | Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide显示文摘AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METHODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful surgeries.RESULTS: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model. | Tomohide Hori Justin H Nguyen Yasuhiro Ogura Toshiyuki Hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara Motohiko Yasutomi Shinji Uemoto | 2010 | World Journal of Gastroenterology2010，16，25： | 14 |
| 2 | Dynamic viscoelastic study on the gelation of 7S globulin from soybean 显示文摘 | Takao N Motohiko H Hiroyuki M | 1992 | Journal of Agricultural and Food Chemistry1992，48，： | 1 |
| 3 | Hypoxia-indueed changes in the expression of VEGF, HIF-1α and cell eyele-ralated molecules in ovarian cancer cell显示文摘 | Akiko H Tsutomu I Motohiko S | 2002 | Antieaeer Res2002，22，5： | 1 |
| 4 | Hypoxia-induced changes in the expression of VEGF,HIF-1 aand cell cycle-related molecules in ovarian cancer cell显示文摘 | Akiko H Tsutoran l Motohiko S | 2002 | Anticaeer Res2002，22，： | 1 |
| 5 | Hypoxia-induced changes in the expression of VEGF,HIF-1αand cell cycle-ralated molecules in ovarian cancer cell显示文摘 | Akiko H Tsutomu I Motohiko S | 2002 | Anticacer Res2002，22，： | 1 |
| 6 | simulation of concrete-frame collapse dynamic loading显示文摘 | Motohiko H akuno K imiro Meguo | 1993 | Journal of Engineering Mechanics1993，119，9： | 1 |
| 7 | Simulation of concrete frame collapse due to dynamic loading 显示文摘 | Motohiko H Kimiro M | 1993 | Journal of Engi- neering Mechanics1993，119，9： | 1 |
| 8 | Multi-layered flyer accelerated by laser induced shock waves显示文摘 | Tanaka K A Motohiko H Norimasa O | 2000 | Physics of Plasmas2000，7，2： | 1 |
| 9 | Simulation of concrete-frame collapse due to dynamic loading显示文摘 | Motohiko H Kimiro M | 1993 | Journal of Engi- neering Mechanics1993，119，： | 1 |
| 10 | Wind-induced dynamic response and resultant load estimation of a circular flat roof 显示文摘 | YASUSHI U KEISUKE W AKIHIRO S MOTOHIKO Y TAKESHI H | 1999 | Journal of Wind Engineering and Industrial Aerodynamic1999，83，： | 1 |
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