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3篇 您的检索式:作者名="Muhammad Aqeel BHUTTO"
    题名 作者 年代 出处 被引量
1Production of pectinase by Bacillus subtilis EFRL 01 in a date syrup medium显示文摘Abdul Sattar Qureshi Muhammad Aqeel Bhutto Yusuf Chisti 0,,62:1
2Double‑Layer Nanofibrous Sponge Tube via Electrospun Fiber and Yarn for Promoting Urethral Regeneration显示文摘Insufficient bionic performance is a structural obstacle and makes urethral repair unobtainable.To overcome this challenge,we mimicked the urethral matrix and applied two electrospinning techniques to build a double-layer sponge tube of nanofib-ers and nanoyarns.Intriguingly,silk fibroin(SF)and vitamin B5(VitB5)could be introduced to increase the elasticity of the outer layer and reduce the hydrophobicity to further improve mesenchymal cell proliferation.Systematic experiments validated the bionic structure,biocompatibility,and exosome delivery capacity in this scaffold.We achieved scarless urethral repair by delivering the bioactive growth factors from adipose-derived stem cell exosomes by physical absorption.Biological regeneration of the urethra can be accomplished with continuous epithelium in animals.Furthermore,bioinformatics studies revealed that the expression of cell proliferation and fibrotic genes(e.g.,Wnt7a,cfa-miR-574)was responsible for the bio-logical regeneration of the adipose-derived stem cells exosomes(ADSC-exos)by delivering poly l-lactide-co-caprolactone/SF/VitB5 bilayer sponge(PSVBS)via reduced fibrosis gene expression,as well as improved epithelial formation and blood vessel formation.Therefore,the PSVBS design appeared to be an instructive approach for urethral and other tubular organ regeneration.Kaile Zhang Muhammad Aqeel Bhutto Liyang Wang Kai Wang Jie Liu Wenyao Li Wenguo Cui Qiang Fu 2023Advanced Fiber Materials2023,5,2:0
3Fabrication and characterization of Antheraea pernyi silk fibroin-blended P(LLA-CL) nanofibrous scaffolds for peripheral nerve tissue engineering显示文摘Juan WANG Binbin SUN Muhammad Aqeel BHUTTO Tonghe ZHU Kui YU Jiayu BAO Yosry MORSI Hany EL-HAMSHARY Mohamed EL-NEWEHY Xiumei MO 2017Frontiers of Materials Science2017,11,1:0
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