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257篇 您的检索式:作者名="Murphy I"
    题名 作者 年代 出处 被引量
1成人、儿童及孕妇特发性血小板减少性紫癜诊治指南显示文摘特发性血小板减少性紫癜(ITP)是一种自体免疫性疾病,以持续性血小板减少为特征(血小板<150×109/L).其发病机理是自身抗体与血小板抗原结合导致它们在未成熟时即被网状内皮系统,特别是在脾脏中被破坏引起血小板减少.Provan D Newland A Norfolk D Bolton-Maggs P Lilleyman J Greer I May A Murphy M Ouwehand W Watson S 李振宇 徐开林 2004国外医学(输血及血液学分册)2004,27,4:25
2Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting.Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov 2014World Journal of Gastroenterology2014,20,45:9
3系统性药物治疗儿童银屑病的安全性显示文摘银屑病是一种常见的慢性炎症性皮肤病。成年人的发病率为2%~3%,其中大约有三分之一的患者在18岁之前发病。在儿童期,该病的发病率呈线性增长。从1970年至2000年,儿童银屑病的发病率增加了一倍多。尽管对许多轻度银屑病患儿而言,局部治疗已足够,但对更多可能影响生活质量的重度或顽固性的银屑病患儿,则往往需要系统性治疗。bronckers imgj seyger mmb west dp lara-corrales i tollefson m tom wl hogeling m belazarian l zachariae c mahé e siegfried e philipp s szalai z vleugels ra holland k murphy r baselga e cordoro k lambert j alexopoulos a mrowietz u kievit w paller as 邓婕(编译) 张锡宝(审校) 2017皮肤性病诊疗学杂志2017,24,5:3
4Identification of phase separation in solid dispersions of itraconazole and Eudragit(R) E100 using microthermal analysis显示文摘 Murphy J Weuts I 2003Pharm Res2003,20,1:1
5LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware 1998Immunity1998,,:1
6Nonsurgical breast enlargement using an external soft-tissue expansion system显示文摘Khouri RK Schlenz I Murphy BJ 2000Plast Reconstr Surg2000,105,7:1
7Fractional metals in street dust of a mixed land use sewershed, Hamilton, Ontario 显示文摘Droppo I G Irvine K N Murphy T P 1998Hydrology in a Changing Environment Ⅲ1998,,:1
8Geochemistry of pelagic and hemipelagic carbonates:criteria for identifying systems tracts and sea-level change显示文摘JARVIS I MURPHY A M GALE A S 2001Journal of Geological Society2001,158,:1
9Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial显示文摘WHUTE R I CROWNOVER R MURPHY M J 2003Ann Thorac Surg2003,75,4:1
10Toxicity of engineered nanoparticles in the environment显示文摘Maurer-Jones M A Gunsolus I L Murphy C J 2013Anal Chem2013,85,6:1
11Aortoiliac insufficiency: long - term experience with stent placement for treatment 显示文摘MURPHY T P ARIARATNAM N S CARNEY W I 2004Radiology2004,23,1:1
12Use of bacteriophage for the selective isolation of thermophilic actinomycetes from composted eucalyptus bark显示文摘KURTBOKE D I MURPHY N E SIVASITHAMPARAM K 1993Canadian Journal of Microbiology1993,39,:1
13Nitrogen-form and endophyte-infection effects on growth, nitrogen uptake, and alkaloid content of chewings fescue turfgrass显示文摘Richardson M D Cabrera R I Murphy J A 1999J Plant Nutrition1999,22,1:1
14Geochemistry of pelagic and hemipelagic carbonates: Criteria for identifying systems tracts and sea-level change显示文摘Jarvis I Murphy A M Gale A S 2001Journal of the Geological Society2001,158,4:1
15Metastasis to the adrenal gland:the emerging role of laparoscopic surgery显示文摘Sarela AI Murphy I Coit DG 2003Ann Surg Oncol2003,10,:1
16Metastasis to the adrenal gland:the emerging role of laparoscopic surgery显示文摘Sarela AL Murphy I Coit DG 2003Ann Surg Oncol2003,10,:1
17The effect of ecological rehabilitation on vegetation recruitment:some observations from the wettropics of North Queensland显示文摘Tucker N I J Murphy T M 1997Forestry Ecology and Management1997,99,:1
18Continuing Medical Education: MOOCs (Massive Open Online Courses) and Their Implica- tions for Radiology Learning 显示文摘I Murphy K Munk P L 2013Canadian Association of Radiologists Journal2013,64,3:1
19Application of frameless stereotaxy to pedicle screw fixation of the spine显示文摘Kalfas I Kormos D Murphy M 1995J Neurosurg1995,83,:1
20Biotechnology Progress 显示文摘Murphy J C JeweU D L White K I 200319(3): 982-9862003,19,3:1
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