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| 1 | Helicobacter pylori infection is not associated with nonalcoholic fatty liver disease显示文摘AIM: To determine whether Helicobacter pylori(H. pylori) infection confers a higher risk of Nonalcoholic fatty liver disease(NAFLD).METHODS: Healthy people who underwent health screening were analyzed retrospectively. Inclusion criteria were age ≥ 20 years, history of H. pylori infection, and recorded insulin level. Participants were classified as H. pylori positive or negative according to 13 C urea breath tests. NAFLD was defined using the hepatic steatosis index(HSI) and NAFLD liver fat score(NAFLD-LFS). Those with an HSI > 36 or NAFLD-LFS >-0.640 were considered to have NAFLD. Multivariable logistic regression was performed to identify risk factors for NAFLD.RESULTS: Three thousand six hundred and sixtythree people were analyzed and 1636(44.7%) were H. pylori positive. H. pylori infection was associated with older age, male gender, hypertension, higher body mass index, and a dyslipidemic profile. HSI differed significantly between H. pylori positive and negative subjects(median 33.2, interquartile range(IQR) 30.0-36.2 for H. pylori-positive vs median 32.6, IQR 29.8-36.0 for negative participants, P = 0.005), but NAFLD-LSF did not [median-1.7, IQR-2.4--0.7 vs median-1.8, IQR-2.4-(-0.7), respectively, P = 0.122]. The percentage of people with NAFLD did not differbetween infected and uninfected groups: HIS, 26.9% vs 27.1%, P = 0.173; NAFLD-LFS, 23.5% vs 23.1%, P = 0.778. H. pylori infection was not a risk factor, but C-reactive protein concentration and smoking were significant risk factors for NAFLD.CONCLUSION: H. pylori infection is not a risk factor for NAFLD as indicated by HSI or NAFLD-LFS. Prospective, large-scale studies involving liver biopsies should be considered. | Myong Ki Baeg Seung Kew Yoon Sun-Hye Ko Yong-Sun Noh In-Seok Lee Myung-Gyu Choi | 2016 | World Journal of Gastroenterology2016，22，8： | 12 |
| 2 | Increased liver markers are associated with higher risk of type 2 diabetes显示文摘AIM: To investigate the association between liver markers and the risk of type 2 diabetes(T2DM) and impaired fasting glucose(IFG).METHODS: A total of 8863 participants(3408 men and 5455 women) over 30 years of age were analyzed from the fifth Korean National Health and Nutrition Examination Survey(2010-2011). The associations of serum liver markers such as aspartate aminotransferase(AST), alanine aminotransferase(ALT), AST/ALT, and gamma-glutamyltransferase(GGT) with T2 DM and IFG were analyzed using logistic regression models. Participants were divided into sex-specific quartiles on the basis of liver markers.RESULTS: The prevalence of T2 DM and IFG were 11.3% and 18.3%. Increasing quartiles of ALT and GGT were positively and AST/ALT were negatively correlated with T2 DM and IFG. Analysis of the liver marker combinations showed that if any two or more markers were in the highest risk quartile, the risks of both T2 DM and IFG increased significantly. The risk was greatest when the highest ALT and GGT and lowest AST/ALT quartile were combined, with the riskof T2 DM at 3.21(95%CI: 1.829-5.622, P < 0.001) in men and 4.60(95%CI: 3.217-6.582, P < 0.001) in women. Men and women with the highest AST and ALT and lowest AST/ALT quartile had a 1.99 and 2.40 times increased risk of IFG.CONCLUSION: Higher levels of GGT and ALT and lower AST/ALT within the physiological range are independent, additive risk factors of T2 DM and IFG. | Sun-Hye Ko Myong Ki Baeg Kyung-Do Han Seung-Hyun Ko Yu-Bae Ahn | 2015 | World Journal of Gastroenterology2015，21，24： | 8 |
| 3 | Case of inappropriate ADH syndrome:Hyponatremia due to polyethylene glycol bowel preparation显示文摘Colonoscopic screening has been reported to reduce deaths from colorectal cancer.Adequate bowel preparation is essential for this and safety is an important issue in choosing the methods.Polyethylene glycol(PEG)is regarded as a safe method for cleansing,especially compared with oral sodium phosphate.Here,we present a case of hyponatremia caused by the syndrome of inappropriate antidiuretic hormone(ADH)syndrome after PEG precolonoscopic cleansing resulting in generalized tonic-clonic seizures.A 62-year-old women had ingested PEG for precolonoscopic bowel cleansing.While waiting for the colonoscopy,she developed a stuporous mentality and generalized tonic-clonic seizures,which did not correlate with brain magnetic resonance imaging.Her serum sodium level was 113 mEq per liter and laboratory analyses were consistent with inappropriate ADH syndrome.Her thyroid and adrenal functions were normal.There were no malignancies,infections,respiratory disorders or central nervous disorders and she had no history of taking either diuretics or other medications,which might have caused inappropriate ADH syndrome.She was treated with 3%hypertonic saline and showed a complete neurological recovery as her sodium levels recovered.Follow-up visits showed the patient to have a normal sodium level without neurologic deficits.This case shows that inappropriate ADH syndrome can be caused by PEG preparation,which implies that physicians have to be aware of the possible side effects of this colonic cleansing approach and mindful of the possible ensuing symptoms. | Sun-Hye Ko Chul-Hyun Lim Jae-Young Kim Seung Hun Kang Myong Ki Baeg Hyun Jin Oh | 2014 | World Journal of Gastroenterology2014，20，34： | 5 |
| 4 | L形钢管混凝土柱-H型钢梁Z字形拼接节点抗震性能研究显示文摘研究了一种L形钢管混凝土柱-H型钢梁Z字形拼接节点的抗震性能,包括翼缘和腹板均拼接的节点和设置上、下部翼缘加劲肋替代腹板处拼接板的节点。通过对节点的拟静力试验和研究,获得了节点的滞回曲线、滑移荷载、屈服荷载、极限荷载、耗能能力、延性与刚度退化规律,分析腹板处拼接板和翼缘加劲肋对节点抗震性能的影响。研究结果表明:腹板处拼接板可以提高节点的屈服荷载和极限荷载。增加翼缘高强螺栓数量可以提高节点的滑移荷载,但会降低节点的延性性能。垂直加劲肋可以提高节点的屈服荷载、极限荷载和延性。对比有无上、下翼缘加劲肋的两组节点可知,上、下翼缘加劲肋可以提高节点的承载能力,有效传递拼接区的剪力,可代替腹板连接,该节点具有良好的延性和塑性转动能力。 | 刘学春 IM MYONG HAK 陈学森 余少乐 潘钧俊 | 2021 | 建筑结构2021，51，23： | 3 |
| 5 | Analytical solution for one-dimensional nonlinear consolidation of saturated multi-layered soil under time-dependent loading显示文摘This paper presents analytical solutions for one-dimensional nonlinear consolidation of saturated multi-layered soil under time-dependent loading.Analytical solutions are derived for one-dimensional nonlinear consolidation of multi-layered soil subjected to constant loading and ramp loading.The proposed solutions are verified through the comparison with the existing solutions for double-layered soil and singlelayered soil,which shows the proposed solutions are more general ones for one-dimensional nonlinear consolidation of saturated soils subjected to time-dependent loading.Based on the proposed solutions,nonlinear consolidation behavior of saturated multi-layered soil under time-dependent loading is investigated. | Pyol Kim Hyong-Sik Kim Chol-U Pak Chung-Hyok Paek Gun-Hyang Ri Hak-Bom Myong | 2021 | Journal of Ocean Engineering and Science2021，6，1： | 3 |
| 6 | A case of a duodenal duplication cyst presenting as melena显示文摘Duodenal duplication cysts are benign rare congenital anomalies reported mainly in the pediatric population,but seldom in adults.Symptoms depend on the type and location and can present as abdominal pain,distension,dysphagia or dyspepsia.They have been reported to be responsible for duodenal obstruction,pancreatitis and,in rare cases,gastrointestinal bleeding.We present a case of a duodenal duplication cyst in a 43-year-old man presenting as melena.Initial gastroduodenoscopy and colonoscopy did not reveal any bleeding focus.However,the patient began passing melena after 3 d,with an acute decrease in hemoglobin levels.Subsequent studies revealed a duplication cyst in the second portion of the duodenum which was surgically resected.Histology revealed a duodenal duplication cyst consisting of intestinal mucosa.There was no further bleeding and the patient recovered completely.In rare cases,duodenal duplication cysts might cause gastrointestinal bleeding and should be included in the differential diagnosis. | Seung Yeon Ko Sun Hye Ko Sungeun Ha Mi Sung Kim Hyang Mi Shin Myong Ki Baeg | 2013 | World Journal of Gastroenterology2013，19，38： | 2 |
| 7 | Capacity fading of spinel phase LiMn2O4 with cycling显示文摘 | Myong Y S Dong S A Hye R P | 1999 | J Power Sources1999，83，： | 2 |
| 8 | Suppression of laser-induced choroidal neovascularization by intravitreal injection of tristetraprolin显示文摘AIM: To examine the effect of intravitreal adenoviral vector-mediated tristetraprolin(Ad-TTP) on VEGF m RNA expression in a rat model of laser-induced choroidal neovascularization.METHODS: Ad-TTP was prepared using a commercial kit. Retinal laser-induced photocoagulation(10 spots per eye) was performed on rats in this experimental choroidal neovascularization(CNV) model. Rats were divided into four groups: control(single intravitreal injection of balanced salt solution, n =10), laser-induced CNV(photocoagulation only, n =20), laser-induced CNV plus Ad-TTP injection(photocoagulation plus a single intravitreal Ad-TTP injection, n =20) and Ad-TTP injection only(n =10). Changes in choroidal morphology were evaluated in ten rats in the laser only and the laser plus Ad-TTP groups. Two weeks after laser injury, the size of CNV was calculated by perfusion with high-molecular-weight fluorescein isothiocyanate(FITC)-dextran. VEGF m RNA expression in retina-choroid tissue from ten rats in each group was measured by reverse transcription polymerase chain reaction(RT-PCR). RESULTS: Two weeks after treatment, the area of laser-induced CNV was reduced by approximately 60% in the rats given the Ad-TTP injection compared with that in the laser-only group. There was a tendency toward decreased VEGF m RNA expression in the Ad-TTP injection groups.CONCLUSION: A single intravitreal injection of Ad-TTP significantly suppressed CNV size in this experimental laser-induced CNV model. Ad-TTP injection also decreased VEGF m RNA expression compared with that inthe laser-induced CNV group. The present study is meaningful as the first study to investigate the effect of tristetraprolin delivered via intravitreal injection. | Yong Wun Cho Yong Seop Han In Young Chung Seong Jae Kim Seong Wook Seo Ji Myong Yoo Jong Moon Park | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 2 |
| 9 | Simulated nitrogen inputs influence methane and nitrous oxide fluxes from a young larch plantation in northern Japan显示文摘 | Yong Suk Kim Masakazu Imori Makoto Watanabe Ryusuke Hatano Myong Jong Yi Takayoshi Koike | 2011 | Atmospheric Environment2011，，： | 2 |
| 10 | Flammable carbon nanotube transistors on a nitrocellulose paper substrate for transient electronics显示文摘短暂电子学代表包括能响应刺激以一种控制方式消失的材料的技术的一个新兴的班。与被设计在最长可能的时期上操作的常规电子设备相对照,短暂电子学被操作在一个短、明确的时期上典型地定义;当不再需要时,短暂电子学经历 self-deconstruction 并且完全消失。在这个工作,明确地,我们基于纸底层表明热地触发的短暂电子设备的制造一份硝化纤维素报纸。因为它由被暴露被 nitrating 纤维素形成到硝酸的高度易燃的部件组成,硝化纤维素纸经常在魔力的行为被使用。因此,没有生产任何残余,在硝化纤维素纸上制作的电子设备的完全、快速的破坏是可能的(即,灰) 。顷刻率能被控制收音机频率修改被用于银(Ag ) 的导致信号的电压抵抗加热器,它在硝化纤维素纸的背后上被印上。Ag 抵抗加热器被简单、便宜踩的制造准备,它不要求严厉化学药品或复杂热处理。为硝化纤维素纸底层上的电子学,我们采用了半导体的碳 nanotube (CNT ) 在为优异电、机械的性质的晶体管的网络隧道。 | Jinsu Yoon Juhee Lee Bongsik Choi Dongil Lee Dae Hwan Kim Dong Myong Kim Dong-II Moon Meehyun Lim Sungho Kim Sung-Jin Choi | 2017 | Nano Research2017，10，1： | 2 |
| 11 | Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice显示文摘AIM: To evaluate the efficacy of Myelophil, an extract containing Astragali Radix and Salviae Radix, for reducing complications induced by 5-fluorouracil (5-FU) in a gastrointestinal cancer model. METHODS: We injected 5-FU into mice and then administered Myelophil to examine the ability of the drug to treat the side effects of 5-FU in mice. Peripheral blood counts, histological examinations, and colony-forming assays of bone marrow were conducted, followed by swimming tests and assessment of survival times. RESULTS: Myelophil restored red and white blood cells and platelets in blood, and recovered cell density in bone marrow to levels comparable to those observed within the control group. In addition, Myelophil significantly increased colony-forming unit granulocyte-macrophage (CFU-GM) and CFU-erythroid (CFU-E) compared to the control group. We confirmed that interleukin-3 gene expression was upregulated by Myelophil in spleen cells. Myelophil administration also doubled the survival rate of mice that were severely myelosuppressed as a result of 5-FU injection at a lethal dose of 70%. Finally, the swimming performance of mice significantly improved as a result of Myelophil treatment. CONCLUSION: These results provide experimentalevidence in support of clinical applications of Myelophil to minimize 5-FU-induced myelosuppression and improve general post-chemotherapy health. | Jang Woo Shin Myong Min Lee Jin Young Son Nam Heon Lee Chong Kwan Cho Won Kyu Chung Jung Hyo Cho Chang Gue Son | 2008 | World Journal of Gastroenterology2008，14，15： | 2 |
| 12 | Effect of DA-9701 on gastric emptying in a mouse model: Assessment by ^(13)C-octanoic acid breath test显示文摘AIM:To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the 13C-octanoic acid breath test in a mouse model. METHODS:Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 mg of egg yolk labeled with 1.5 L/g 13C-octanoic acid. The mice were placed in a 130 mL chamber flushed with air at a flow speed of 200 mL/min. Breath samples were collected for 6 h. The half-emptying time and lag phase were calculated using a modified power exponential model. To assess the reproducibility of the 13C-octanoic acid breath test, the breath test was performed two times at intervals of one week in ten mice without drug treatment. To assess the gastrokinetic effects of DA-9701, the breath test was performed three times in another twelve mice, with a randomized crossover sequence of three drug treatments:DA-9701 3 mg/kg, erythromycin 6 mg/kg, or saline. Each breath test was performed at an interval of one week. RESULTS:Repeatedly measured half gastric emptying time of ten mice without drug treatment showed 0.856 of the intraclass correlation coefficient for the half gastric emptying time (P = 0.004). The mean cumulative excretion curve for the 13C-octanoic acid breath test showed accelerated gastric emptying after DA-9701 treatment compared with the saline control (P = 0.028). The median half gastric emptying time after the DA-9701 treatment was significantly shorter than after the saline treatment [122.4 min (109.0-137.9 min) vs 134.5 min (128.4-167.0 min), respectively; P = 0.028] and similar to that after the erythromycin treatment [123.3 min (112.9-138.2 min)]. The lag phase, which was defined as the period taken to empty 15% of a meal, was significantly shorter after the DA-9701 treatment than after the saline treatment [48.1 min (44.6-57.1 min) vs 52.6 min (49.45-57.4 min), respectively; P = 0.049]. CONCLUSION:The novel prokinetic agent DA-9701 accelerated gastric emptying, assessed with repeated measurements in the same mouse using the 13Coctanoic acid breath test. Our findings suggest that DA-9701 has therapeutic potential for the treatment of functional dyspepsia. | Chul-Hyun Lim Myung-Gyu Choi Hyeyeon Park Myong Ki Baeg Jae Myung Park | 2013 | World Journal of Gastroenterology2013，19，27： | 2 |
| 13 | Low noise bipolar photodiode array protein chip based on on-chip bioassay for the detection of E. coli O157:H7显示文摘 | Min Jung Kim Min-Sung Yang Ho Taik Kwon Joon Myong Song | 2007 | Biomedical Microdevices2007，，4： | 2 |
| 14 | Enhanced photocatalytic degradation of lindane using metal–semiconductor Zn@ZnO and ZnO/Ag nanostructures显示文摘To achieve enhanced photocatalytic activity for the degradation of lindane, we prepared metal–semiconductor composite nanoparticles(NPs). Zn@ZnO core–shell(CS) nanocomposites, calcined ZnO, and Ag-doped ZnO(ZnO/Ag) nanostructures were prepared using pulsed laser ablation in liquid, calcination, and photodeposition methods, respectively, without using surfactants or catalysts. The as-prepared catalysts were characterized by using X-ray diffraction(XRD), field-emission scanning electron microscopy, high-resolution transmission electron microscopy, ultraviolet–visible(UV–vis) spectroscopy, and photoluminescence spectroscopy. In addition, elemental analysis was performed by energy dispersive X-ray spectroscopy. The obtained XRD and morphology results indicated good dispersion of Zn and Ag NPs on the surface of the ZnO nanostructures. Investigation of the photocatalytic degradation of lindane under UV–vis irradiation showed that Zn@ZnO CS nanocomposites exhibit higher photocatalytic activity than the other prepared samples. The maximum degradation rate of lindane was 99.5% in 40 min using Zn@ZnO CS nanocomposites. The radical trapping experiments verified that the hydroxyl radical(·OH) was the main reactive species for the degradation of lindane. | Hyeon Jin Jung Ravindranadh Koutavarapu Seulki Lee Ju Hyun Kim Hyun Chul Choi Myong Yong Choi | 2018 | Journal of Environmental Sciences2018，30，12： | 2 |
| 15 | Adaptive support vector regression analysis of closed-loop inspection accuracy显示文摘 | Yongjin Kwon Myong K Jeong Olufemi A Omitaomu | 2006 | International Journal of Machine Tools& Manufacture2006，46，： | 1 |
| 16 | Investigation of curing kinetics of various cycloaliphatic epoxy resins using dynamic thermal analysis显示文摘 | Myong J Y Sang H K Seong D | 2010 | European Polymer Journal2010，46，5： | 1 |
| 17 | The clinical significance of hepatic parenchymal metastasis in patients with primary epithelial ovarian cancer显示文摘 | Myong CL Sokbom K Kyung SL | 2009 | Gynecol Oncol2009，112，1： | 1 |
| 18 | A Wavelet-based Freeway Incident Detection Algorithmwith Adapting Threshold Parameters显示文摘 | Jeong Young-Seon Manoel Castro-Neto Myong K Jeong | 2011 | Transportation Research Part C2011，，19： | 1 |
| 19 | Factors affecting the extraction of lithium from lepidolite显示文摘 | Van Tri Luong Dong Jun Kang Jeon Woong An Myong Jun Kim Tam Tran | 2013 | Hydrometallurgy2013，，： | 1 |
| 20 | Relationship be- tween bone mineral density and moderate to severe chronic kidney disease among general population in ko- rea显示文摘 | Deter Myong JP Kim gR Koo JW | 2013 | Korean Med Sci2013，28，4： | 1 |
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