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| 1 | A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer显示文摘Patients with hormone receptor(HR)-positive tumors breast cancer usually experience a relatively low pathological complete response(p CR)to neoadjuvant chemotherapy(NAC).Here,we derived a 10-micro RNA risk score(10-mi RNA RS)-based model with better performance in the prediction of p CR and validated its relation with the disease-free survival(DFS)in 755 HRpositive breast cancer patients(273,265,and 217 in the training,internal,and external validation sets,respectively).This model,presented as a nomogram,included four parameters:the 10-mi RNA RS found in our previous study,progesterone receptor(PR),human epidermal growth factor receptor 2(HER2)status,and volume transfer constant(K).Favorable calibration and discrimination of 10-mi RNA RS-based model with areas under the curve(AUC)of 0.865,0.811,and 0.804 were shown in the training,internal,and external validation sets,respectively.Patients who have higher nomogram score(>92.2)with NAC treatment would have longer DFS(hazard ratio=0.57;95%CI:0.39–0.83;P=0.004).In summary,our data showed the 10-mi RNA RS-based model could precisely identify more patients who can attain p CR to NAC,which may help clinicians formulate the personalized initial treatment strategy and consequently achieves better clinical prognosis for patients with HRpositive breast cancer. | Chang Gong Ziliang Cheng Yaping Yang Jun Shen Yingying Zhu Li Ling Wanyi Lin Zhigang Yu Zhihua Li Weige Tan Chushan Zheng Wenbo Zheng Jiajie Zhong Xiang Zhang Yunjie Zeng Qiang Liu RStephanie Huang Andrzej LKomorowski Eddy SYang François Bertucci Francesco Ricci Armando Orlandi Gianluca Franceschini Kazuaki Takabe Suzanne Klimberg Naohiro Ishii Angela Toss Mona PTan Mathew A Cherian Erwei Song | 2022 | Science China(Life Sciences)2022，65，11： | 3 |
| 2 | Characteristic fungi observed in fermentation process for puer tea显示文摘 | Michiharu A Naohiro T Yoshito I | 2008 | Inter J of Food Microbiology2008，124，： | 1 |
| 3 | Characteristic fungi observed in the fermentation process for Puer tea 显示文摘 | Miehiharu A Naohiro T Yoshto I | 2008 | International Journal of Food Microbiology2008，124，2： | 1 |
| 4 | Current situation of rice distribution sys- tem in Indonesia显示文摘 | Hiromichi A Naohiro K | 2000 | JBIC Review2000，，1： | 1 |
| 5 | Characteristic fungi observed in the fermentation process for Puer tea显示文摘 | MICHIHARU A NAOHIRO T YOSHITO I | 2008 | International Journal of Food Microbiology2008，124，2： | 1 |
| 6 | Antifungal effect of a heterotrophie nitfifler Alcaligenes faecalis 显示文摘 | NAOHIRO It MITSUYO H TAKASHI A | 1998 | Biotechnology Letters1998，20，7： | 1 |
| 7 | Assessment of P-glycoprotein in patients with malignant bone and soft-tissue tumors using technetium-99m-MIBI scintigraphy显示文摘 | Junichi T Hisashi S Naohiro A | 1998 | J Nucl Med1998，39，10： | 1 |
| 8 | EGFR gets in the way of microRNA biogenesis显示文摘 | Naohiro Nishida Koshi Mimori Masaki Mori George A Calin | 2013 | Cell Research2013，23，10： | 1 |
| 9 | Characteristic fungiobserved in the fermentation process for Puer tea 显示文摘 | Michiharu A Naohiro T Yoshito I | 2008 | International Journal of Food Microbiology2008，124，： | 1 |
| 10 | Overex- pression of a calcium-dependent protein kinase gene enhances growth of rice under low-nitrogen conditions显示文摘 | TAKAYUKI A MASATAKA W NAOHIRO A | 2010 | Plant Biotech- nology2010，27，： | 1 |
| 11 | Influ- ence of aluminum nitride interlayers on crystal orienta- tion and piezoelectric property of aluminum nitride thin films prepared on titanium electrodes显示文摘 | TOSHIHIRO K MORITO A NAOHIRO U | 2007 | Thin Solid Films2007，515，11： | 1 |
| 12 | Convenient test for screening metallo-β-lactamase-producing gram-negative bacteria by using thiol compounds 显示文摘 | Yoshichika A Naohiro S Keigo S | 2000 | J Clin Microbiol2000，38，： | 1 |
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