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| 1 | Non-alcoholic fatty liver disease and diabetes: From physiopathological interplay to diagnosis and treatment显示文摘Non-alcoholic fatty liver disease(NAFLD)is highly prevalent in patients with diabetes mellitus and increasing evidence suggests that patients with type 2diabetes are at a particularly high risk for developing the progressive forms of NAFLD,non-alcoholic steatohepatitis and associated advanced liver fibrosis.Moreover,diabetes is an independent risk factor for NAFLD progression,and for hepatocellular carcinoma development and liver-related mortality in prospective studies.Notwithstanding,patients with NAFLD have an elevated prevalence of prediabetes.Recent studies have shown that NAFLD presence predicts the development of type2 diabetes.Diabetes and NAFLD have mutual pathogenetic mechanisms and it is possible that genetic and environmental factors interact with metabolic derangements to accelerate NAFLD progression in diabetic patients.The diagnosis of the more advanced stages of NAFLD in diabetic patients shares the same challenges as in non-diabetic patients and it includes imaging and serological methods,although histopathological evaluation is still considered the gold standard diagnostic method.An effective established treatment is not yet available for patients with steatohepatitis and fibrosis and randomized clinical trials including only diabetic patients are lacking.We sought to outline the published data including epidemiology,pathogenesis,diagnosis and treatment of NAFLD in diabetic patients,in order to better understand the interplay between these two prevalent diseases and identify the gaps that still need to be fulfilled in the management of NAFLD in patients with diabetes mellitus. | Nathalie C Leite Cristiane A Villela-Nogueira Claudia R L Cardoso Gil F Salles | 2014 | World Journal of Gastroenterology2014，20，26： | 21 |
| 2 | Trace protein,cystain C,2microglobulin,and creatinine compared for detecting impaired glomemlar filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，： | 1 |
| 3 | β2-Trace protein, cystatin C, β2-Microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，5： | 1 |
| 4 | High antifreeze protein levels in wolffish (Anarhichas lupus) make them an ideal candidate for culture in cold, potentially ice laden waters显示文摘 | Marive D Nathalie R L Garth L F | 2007 | Aquaculture2007，272，： | 1 |
| 5 | Trace protein, cystain C, β2- microglobulin, and ereatinine compared for detecting impaired glomemlar filtration rates in children 显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，： | 1 |
| 6 | Soil washing improves the recovery of total community DNA from polluted and high organic content sediments显示文摘 | Nathalie F Danielle B Kneneth L | | 0，，2： | 1 |
| 7 | Characterization of the chicken fatty acid synthase gene 5' part and promoter region显示文摘 | Nathalie L F Catherine E K Powell R S | 1996 | Eur J Biochem1996，240，： | 1 |
| 8 | β2 - Trace protein, cystatin C,β2 - Microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children 显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，5： | 1 |
| 9 | Characterization of the chicken fatty acid synthase gene 5' part and promoter region显示文摘 | NATHALIE L F CATHERINR E K POWELL R S | 1996 | EurJ Biochem1996，240，： | 1 |
| 10 | Trace protein,cystain C,2 microglobulin,and creatinine compared for detecting impaired glomemlar filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，： | 1 |
| 11 | Constitutive activation of a plasma membrane H^+-ATPase prevents abscisic acid-mediated stomatal closure 显示文摘 | Sylvain M Nathalie L Francesca F | 2007 | EMBO J2007，26，13： | 1 |
| 12 | The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis 显示文摘 | Lars E Nathalie F Herve L | 2003 | J Bio Chem2003，278，18： | 1 |
| 13 | The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis 显示文摘 | Lars E Nathalie F Herve L | 2003 | Biol Chem2003，278，18： | 1 |
| 14 | Characterization of the chicken fatty acid synthase gene 5'part and promoter region显示文摘 | Nathalie L F Catherine E K Powell R S | 1996 | Eur J Biochem1996，240，2： | 1 |
| 15 | Trace protein, cystain C,2-microglobulin, and creatinine compared for detecting impaired glomemlar filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，： | 1 |
| 16 | Beta-trace protein,cystatin C,beta(2)-Microglobulin,and creatinine compared for detecting impaired glomerular filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，3： | 1 |
| 17 | Flavonoids for controlling starch digestion: structural requirements for inhibiting human α-amylase 显示文摘 | ELENA L O P HOLGER S NATHALIE F | | J Med Chem0，51，： | 1 |
| 18 | Beta-trace protein, eystatin C, beta (2)-Mieroglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，3： | 1 |
| 19 | HLA-G in transplantation:A Relevant Molecule for inhibition of graft rejection?显示文摘 | Joel L M Philippe M | 2003 | Ame J of Transpl2003，3，： | 1 |
| 20 | Trace protein, cystain C, 2-microglobulin, and creatinine compared for detecting impaired glomemlar filtration rates in children 显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，12： | 1 |
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