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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Liquid - liquid extraction of proteases from fermented broth by PEG/citrate aqueous two-phase system 显示文摘 | Porto T S Silva G M M Porto C S Cavalcanti M T H Neto B B Lima F J L Converti A Porto A L F Pessoa J A | 2008 | Chemical Engineering and Processing2008，47，4： | 1 |
| 3 | Thermal analysis of chitosan based networks 显示文摘 | Neto C G T Giacometti J A Job A E | 2005 | Carbohydrate Polymers2005，62，： | 1 |
| 4 | Thermal analysis ofchitosan based networks 显示文摘 | Neto C G T Giacometti J A Job A E ei al | 2005 | Carbohydrate Polymers2005，62，： | 1 |
| 5 | Endosperm-preferred ex- pression of maize genes as revealed by transcriptome-wide analysis of expressed sequence tags 显示文摘 | Verza N C Esilva T R Neto G C | 2005 | Plant Molecular Biology2005，59，2： | 1 |
| 6 | Kinetics of photocatalytic degradation of reactive dyes in a TiO2 slurry reactor 显示文摘 | Sauer T Neto G C Jose H J Moreira R F P M | 2002 | Journal of Photochemistry andPhotobiologyA-Chemistry2002，149，123： | 1 |
| 7 | Gaseous emissions from a heavy-duty engine equipped with SCR aftertreatment system and fuelled with diesel and biodiesel: assessment of pollutant dispersion and health risk 显示文摘 | Tadano Y S Borillo G C Godoi A F L Cichon A Silva T O B Valebona F B Errera M R Penteado Neto R A Rempel D Martin L Yamamoto C I Godoi R H M | 2014 | Science of the Total Environment2014，，： | 1 |
| 8 | Chitosan maeroporous asymmetric membranes-Preparation,characterization and transport of drugs显示文摘 | SANTOS D E S NETO C G T FONSECA J L C | 2008 | Journal of Membrane Science2008，325，1： | 1 |
| 9 | Use of column with modified silica for interfering retention in a FIA spectrophotometric method for direct determination of vitamin C in medicine显示文摘 | FEMANDES J C B NETO G de O KUBOTA L T | 1998 | Analytica Chimica Acta1998，，366： | 1 |
| 10 | Kinetics of photocatalytic degradation of reactive dyes in a TiO2 slurry reactor 显示文摘 | SAUCER T NETO G C JOSe H J | 2002 | J Photochem Photobiol A Chem2002，149，13： | 1 |
| 11 | Effects of salt stress on antioxidative enzymes and lipid peroxidation in leaves and roots of salt-tolerant and salt-sensitive maize genotypes显示文摘 | NETO A A PRISCO J T JOAQUIM E F ABREU C E ENEAS G F | 2006 | Environmental and Experimental Botany2006，56，： | 1 |
| 12 | Physical and chemical characterization of lamb meat from different genotypes submitted to diet with different fiber contents显示文摘 | Costa R G Batista A S M Madruga M S Neto S G Queiroga R C R E Filho J T A F Villarroel A S | 2009 | Small Ruminant Research2009，81，1： | 1 |
| 13 | Kinetics of photocatalytic degradation of reactive dyes in a TiO2 slurry reactor 显示文摘 | Sauer T Neto G C Jose H J | 2002 | Photochemica Photobiological A : Chem2002，，149： | 1 |
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