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138篇 您的检索式:作者名="NICHOLAS L J"
    题名 作者 年代 出处 被引量
1Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction显示文摘到神经原的精力供应的损失在击期间导致被称为缺氧的去极的膜潜力的快速的损失。因为离子的流动的 dysregulation 和 ATP 的损失,缺氧的去极在神经原上导致巨大的生理的应力驾驶维持电气化学的坡度的离子泵。在这评论,我们在场一些被认为贡献神经原并且随后的缺氧的去极的 ionotropic 受体和离子隧道的概述,到房间死亡。为作为门 ligand 的阳离子隧道工作的 glutamate 和 ATP 的 ionotropic 受体在神经原的死亡和机能障碍是批评的。有趣地,二这些受体(P2X7 和 NMDAR ) 被显示了联合离子隧道到 pannexin-1 (Panx1 ) 。我们也讨论短暂受体潜力(TRP ) 的重要角色响应局部缺血的隧道和酸察觉到的离子隧道(ASIC ) 。从我们缺氧的去极的当前的理解出现的中央挑战是需要阐明这些离子隧道到的机械学、时间的相互关系充分在击期间在神经原上欣赏他们的影响。Nicholas L WEILINGER Valentyna MASLIEIEVA Jennifer BIALECKI Sarup S SRIDHARAN Peter L TANG Roger J THOMPSON 2013Acta Pharmacologica Sinica2013,34,1:5
2DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate显示文摘Mary Premenko-Lanier Paul A Rota Gary Rhodes David Verhoeven Dan H Barouch Nicholas W Lerche Norman L Letvin William J Bellini Michael B McChesney 2003Virology2003,,1:2
3Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine.Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu 2021World Journal of Transplantation2021,11,4:2
4Malaria: current status of control, diagnosis, treatment, and a proposed agenda for research and development显示文摘Philippe J Guerin Piero Olliaro Francois Nosten Pierre Druilhe Ramanan Laxminarayan Fred Binka Wen L Kilama Nathan Ford Nicholas J White 2002The Lancet Infectious Diseases2002,,9:2
5Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft 2010The Lancet Infectious Diseases2010,,12:2
6Diameter-selective encapsulation of metallocenes in single walled carbon nanotubes 显示文摘Li L J Khlobystov A N Wiltshire J G Briggs G A D Nicholas R J 2005Nature Materials2005,4,:1
7The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria显示文摘Elizabeth MH Wellington Alistair BA Boxall Paul Cross Edward J Feil William H Gaze Peter M Hawkey Ashley S Johnson-Rollings Davey L Jones Nicholas M Lee Wilfred Otten Christopher M Thomas A Prysor Williams 2013The Lancet Infectious Diseases2013,,2:1
8Hydrogen peroxide production by Mycoplasma bovis and Mycoplasma agalactiae and effect of in vitro passage on a Mycoplasma bovis strain producing high levels of hydrogen peroxides 显示文摘Khan L A Miles R J Nicholas R A 2005Vet Res2005,29,:1
9Diameter-selective encapsulation of metallocenes in single walled carbon nanotubes 显示文摘Li L J Khlobystov A N Wiltshire J G Briggs G A D Nicholas R J 2005Nature Materials2005,4,:1
10Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos显示文摘 Rubenstein J L Nicholas J F 1986EMBO J1986,5,12:1
11Prediction and evaluation of sintering aids for cerium gadolinium oxide显示文摘Nicholas J D de Jonghe L C 0,,:1
12Temperature and the expression of myogenic regulatory factors(MRFs) and myosin heavy chain isoforms during embryogenesis in the com- mon carp Cyprinus carpin L显示文摘Nicholas J Thomas E H Christopher L 2004J Expel Biol2004,207,24:1
13High cycle fatigue behavior of Ti 6Al-4V with simulated foreign object damage显示文摘Mall S Hamrick J L Nicholas T 0,,11:1
14Spectroscopic probe analysis of protein - emulsifier interactions : the BSA/SDS system 显示文摘Nicholas Turro J Gong L X 1995Langmuir1995,,11:1
15Long-stem revision prosthesis for salvage of failed fixation of extracapsular显示文摘Rory J Sharvil L Nicholas A 2009Arta Orthop Belg2009,75,3:1
16Optical probing of the minigap in InAs/GaSb superlattices显示文摘Poulter A J L Lakrimi M Nicholas R J 0,,:1
17Frequency and stress ratio effects in high cycle fatigue of Ti 6Al 4V显示文摘Morrissey R J McDowell D L Nicholas T 1999International Journal of Fatigue1999,21,:1
18Epimerization of aldoes by molybdate involving a novel rearrangement of the carbon skeleton显示文摘 Nicholas J P Anthony S S 1982J Am Chem Soc1982,104,:1
19Variation of proline rich cell wail proteins in soybean lines with anthocyanin mutations 显示文摘Nicholas C D Lindstrom J T Vodkin L O 1993Plant Mol Bio11993,21,:1
20Lagrange constraints for transient finite element surface contact 显示文摘Carpenter Nicholas J Taylor Robert L Katona Michael G 1991International Journal for Numerical Methods in Engineering1991,32,1:1
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