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| 1 | Portal vein thrombosis:Prevalence,patient characteristics and lifetime risk:A population study based on 23796 consecutive autopsies显示文摘瞄准:估计一生在一般人口的门静脉血栓形成(PVT ) 的累积发生。方法:在 1970 和 1982 之间, 23,796 具尸体,在马尔摩城市人口代表 84% 所有在里面医院死亡,被执行,用包括门静脉的检查的一个 standardised 协议。PVT 病人被描述并且在尸体的 PVT 流行,一生的表情累积发生,在高风险的疾病范畴估计了并且以机会比率和 95% CI 表示了。结果:PVT 的人口流行是 1.0% 。有 PVT 28% 的 254 个病人有肝硬化, 23% 主要并且 44% 第二等的肝胆管恶意, 10% 主要腹的传染或煽动性的疾病并且 3% 有 myeloproliferative 混乱。有肝硬化和肝的癌的病人有最高的 PVT 风险,或 17.1 (95% CI 11.1-26.4 ) 。在 14% ,没有原因被发现;仅仅,少数他们开发了 portal-hypertension-related 复杂并发症。结论:在这基于人口的研究, PVT 比由以前的临床的系列显示被发现更普通。显著地,在肝硬化和肝的癌的过量风险应该在指导干预的未来的研究可能为被考虑的这些病人保证增加的了解。 | Mats gren David Bergqvist Martin Bjrck Stefan Acosta Henry Eriksson Nils H Sternby | 2006 | World Journal of Gastroenterology2006，12，13： | 66 |
| 2 | 公司债券市场在经济和避免危机中的作用显示文摘尽管人们非常关注公司的最佳负债权益结构,却忽略了债券融资与(长期)银行融资之间的“最优”或最佳平衡。本文分析了不受政府干预的、成熟的公司债券市场的经济与以银行融资为主的经济(如在东亚)的主要差别。当出现非常成熟的公司债券市场时,市场力量会有更多的机会来自我决断,从而降低系统风险和危机发生的可能。因为,与这种环境相联系的是:更加透明的会计制度、大量的财务分析人员、信誉良好的评级公司、需要进行复杂信用分析的各种公司债券和衍生工具以及公司重组和清算的有效程序。此外,丰富的证券种类可以提高经济效益,而且影响债券价格的市场力量有可能尉银行系统的健康性产生较强的间接效应。 | 尼尔斯·H·霍坎松(Nils H.Hakansson) 夏冬林(译者) 刘柱(译者) | 1999 | 中国会计与财务研究1999，，1： | 4 |
| 3 | Cerebral venous thrombosis and heparin-induced thrombocytopenia in an 18-year old male with severe ulcerative colitis显示文摘The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescent boy who developed a cerebral sinus venous thrombosis during a relapse of his ulcerative colitis and who, while on treatment with heparin, developed heparin-induced thrombocytopenia (HIT). The treatment was then switched to fondaparinux, a synthetic and selective inhibitor of activated factor . | Gudrun Scheving Thorsteinsson Maria Magnussson Lena M Hallberg Nils Gunnar Wahlgren Fredrik Lindgren Petter Malmborg Thomas H Casswall | 2008 | World Journal of Gastroenterology2008，14，28： | 4 |
| 4 | 瑞典沿海生境生态系统的物产与服务:生态系统变迁的鉴别、评估和意义显示文摘人口高密度和经济快速发展使沿海地区处于多种威胁之中。这种状况如何影响人类福利及人类对生态系统物产与服务的依赖呢?本文首次对温带地区沿海主要生境(大型海藻、海草、翡翠贻贝床和无植被软海底)的生态系统物产与服务状况进行了评估。作者将40多种物产和服务细分为供给服务、调节服务和文化服务。作者列举了各类中瑞典境内各种生态系统服务的实例,包括经济价值和不同生境相对重要性评估。例如,具有极大重要性的翡翠贻贝对缓解富营养化的作用、沙质海滩的休闲娱乐功能、海草和大型藻类对渔产、波浪能和海流能的作用。本文评估了3种沿海生态系统变化对生态系统物产与服务的影响:1)海草床变为无植被海底;2)无植被浅水软海底向丝状藻类基质转变;3)坚硬基质上大型藻类向贻贝的转变。文章结尾部分对生物多样性评估、生态系统的普遍联系性和潜在经济价值等从管理角度进行了讨论。 | Patrik Rnnbck Nils Kautsky Leif Pihl Max Troell Tore Sderqvist Hkan Wennhage 梁虹 | 2007 | AMBIO-人类环境杂志2007，36，B11： | 2 |
| 5 | Modeling electricity auction显示文摘 | Natalia F Nils H F David H | 2002 | The Electricity Journal2002，15，7： | 1 |
| 6 | Broadband Nois- esource Localization by Line Microphone Array Positioned Near a Wind Turbine Rotor Blade 显示文摘 | Nil Y Takahashi N Matsumiya H | 2000 | Furyoku Enerugi Riyo Shinpojiumu2000，22，： | 1 |
| 7 | Effect of Randomness on Fer- roelastlc Transitions:Disorder-Induced Hysteresis Loop Rounding in Ti-Nb-O Martensitic Alloy显示文摘 | Nil Y Arima T Kim H Y | | 0，，： | 1 |
| 8 | Effects of cyclic freezing and thawing on mechanical properties of Qinghai-Tibet clay 显示文摘 | WANG D Y MA W NIL/Y H | 2007 | Cold Regions Science and Technology2007，48，： | 1 |
| 9 | Fine scale distribution of eetomycorrhizal fungi and roots across substrate layers in- cluding coarse woody debris in a mixed forest显示文摘 | LEHO T URMAS K NILS H | 2003 | New Phy- tologist2003，159，1： | 1 |
| 10 | The selective adenosine A1 receptor antagonist KW-3902 prevents radiocontrast media-induced nephropathy in rats with chronic nitric oxide deficiency显示文摘 | Kozo Y Nils H Christiane ME | 2001 | Eur J Phar2001，23，： | 1 |
| 11 | Impor- tance of soil calcium for composition of understory vegetation in boreal forests of Finnish Lapland 显示文摘 | Paavo N Maarit M Nils G Eija H Marja L S Raimo S | 2011 | Biogeochemistry2011，102，： | 1 |
| 12 | Initial indications of abiotic formation of hydrocarbons in the rainbow ultramafic hydrothermal system,Mid-Atlantic Ridge显示文摘 | Nils G H Jean L C | 2001 | Earth and Planetary Science Letters2001，191，12： | 1 |
| 13 | Upper-extremity deep vein thrombosis: a prospective registry of 592 patients显示文摘 | Joffe H V Nils K Tapson V F | 2004 | Circulation2004，110，12： | 1 |
| 14 | Paleocurrent direction measure- ments in a volcanic setting by means of anisotropy of magnetic sus- ceptibility: A case study from the Lower Miocene Tepozd6n For- mation(Transmexican Volcanic Belt, Central Mexico)显示文摘 | Nils L Harald B Matthias H | 2013 | Sedimen- tary Geology2013，290，： | 1 |
| 15 | Implementation and verification of a low-power UHF/LF wireless sensor network as part of the intelligent container显示文摘 | Nils H Steffen J Walter L | 2012 | Procedia Engineering2012，47，： | 1 |
| 16 | FOLFIRI3-aflibercept in previously treated patients with metastatic colorectal cancer显示文摘AIM To evaluate the efficacy and safety of the modified FOLFIRI3-aflibercept as second-line therapy in patients with metastatic colorectal cancer.METHODS This is a retrospective multicenter cohort, evaluating the efficacy and safety of the association of aflibercept with FOLFIRI3(day 1: aflibercept 4 mg/kg, folinic acid 400 mg/m^2, irinotecan 90 mg/m^2, 5-fluorouracil infusion 2400 mg/m^2 per 46 h; day 3: irinotecan 90 mg/m^2) in patients with previously treated metastatic colorectal cancer. The primary endpoint was overall response rate(ORR). Secondary endpoints were disease control rate(DCR), progression-free survival(PFS), overall survival(OS), and safety.RESULTS Among 74 patients treated in four French centers, nine were excluded due to prior use of aflibercept(n = 3), more than one prior treatment line in irinotecanna?ve patients(n = 3), and inadequate liver function(n = 3). In the 'irinotecan-na?ve' patients(n = 30), ORR was 43.3% and DCR was 76.7%. Median PFS and OS were 11.3 mo(95%CI: 6.1-29.0) and 17.0 mo(95%CI: 13.0-17.3), respectively. The most common(> 5%) grade 3-4 adverse events were diarrhea(37.9%), neutropenia(14.3%), stomatitis and anemia(10.4%), and hypertension(6.7%). In the 'pre-exposed irinotecan' patients(n = 35), 20(57.1%) received ≥ 2 prior lines of treatment. ORR was 34.3% and DCR was 60.0%. Median PFS and OS were 5.7 mo(95%CI: 3.9-10.4) and 14.3 mo(95%CI: 12.8-19.5), respectively.CONCLUSION Minimally modified FOLFIRI has improvement dramatically the FOLFIRI3-aflibercept efficacy, whatever prior use of irinotecan. A prospective randomized trial is warranted to compare FOLFIRI-aflibercept to FOLFIRI3-aflibercept. | CANDice Carola Fran?ois Ghiringhelli Stefano Kim Thierry ANDré Juliette Barlet Le?la Bengrine-Lefevre Hélène Marijon Marie-Line Garcia-Larnicol Christophe Borg Linda Dainese Nils Steuer Hubert Richa Magdalena Benetkiewicz Annette K Larsen Aimery de Gramont Benoist Chibaudel | 2018 | World Journal of Clinical Oncology2018，9，5： | 1 |
| 17 | Phase transition in PbTiO3 under pressure studied by the first - principles method 显示文摘 | LIU Y NIL H XU G | 2008 | Physica B : Condensed Matter2008，403，： | 1 |
| 18 | Coupling remote sensing with computational fluid dynamics modelling to estimate lake chlorophyll-a concentration 显示文摘 | Richard D H Nils R B O Malthus T J | 2002 | Remote Sensing of Environment2002，79，： | 1 |
| 19 | Molecular Dynamics Simulations and Structure-Guided Mutagenesis Provide Insight into the Architecture of the Catalytic Core of the Ectoine Hydroxylase显示文摘 | Nils Widderich Marco Pittelkow Astrid Hppner | 2014 | Journal of Molecular Biology2014，426，3： | 1 |
| 20 | Evaluation of TGO growth in thermal barrier coatings using impedance spectroscopy显示文摘 | HUANG H LIU C NIL Y | | 0，，01： | 1 |
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