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| 1 | Study on air flow dynamic characteristic of mechanical ventilation of a lung simulator显示文摘As an important life support treatment, mechanical ventilation is usually adopted in clinics. With the development of the res-piratory diagnostic and treatment technologies, air flow dynamics of mechanical ventilation is usually referenced in the evaluation of pulmonary status and assessment of respiratory therapy. In order to improve the ventilation efficiency and provide a reference for pulmonary diagnostics, in this paper, a new mathematical model of mechanical ventilation system was set up. Furthermore, a prototype mechanical ventilation system for an artificial simulating lung was designed and experimentally studied. Lastly, in order to improve the ventilation efficiency and provide a reference for pulmonary diagnostics, the air flow dynamics of the mechanical ventilation system was illustrated through simulation and experimental studies. The study can be helpful to the optimization of the mechanical ventilation system. | NIU JingLong SHI Yan CAO ZhiXin CAI MaoLin CHEN Wei ZHU Jian XU WeiQing | 2017 | Science China(Technological Sciences)2017，60，2： | 8 |
| 2 | Effect of electric intensity on the microbial degradation of petroleum pollutants in soil显示文摘Electro-bioremediation is an innovative method to remedy organic-polluted soil. However, the principle of electrokinetic technology enhancing the function of microbes, especially the relationship of electric intensity and biodegradation efficiency, is poorly investigated. Petroleum was employed as a target organic pollutant at a level of 50 g/kg (mass of petroleum/mass of dry soil). A direct current power supply was used for tests with a constant direct current electric voltage (1.0 V/cm). The petroleum concentrations were measured at 3275–3285 nm after extraction using hexane, the group composition of crude oil was analyzed by column chromatography. The water content of soil was kept 25% (m/m). The results indicated the degradation process was divided into two periods: from day 1 to day 40, from day 41 to day 100. The treatment of soil with an appropriate electric field led the bacteria to have a persistent effect in the whole period of 100 days. The highest biodegradation efficiency of 45.5% was obtained after treatment with electric current and bacteria. The electric-bioremediation had a positive effect on alkane degradation. The degradation rate of alkane was 1.6 times higher in the soil exposed to electric current than that treated with bacteria for 100 days. A proper direct current could stimulate the microbial activities and accelerate the biodegradation of petroleum. There was a positive correlation between the electric intensities and the petroleum bioremediation efficiencies with a coefficient of 0.9599. | Tingting Li Shuhai Guo Bo Wu Fengmei Li Zhixin Niu | 2010 | Journal of Environmental Sciences2010，22，9： | 6 |
| 3 | Working characteristics of a new ventilator with automatic secretion clearance function显示文摘Secretions in the airways of ventilated patients must be cleared efficiently and timely. A novel ventilator(SC ventilator) is proposed with an automatic secretion clearance function in order to provide a new approach. A mathematical model of a ventilation system with the SC ventilator is set up to optimize the SC ventilator. Based on the research, conclusion can be reached as follows. First, the experimental results and the mathematical model are proved to be authentic and reliable. Second, the secretion clearance efficiency of the SC ventilator may be higher than that of IL-IE device. Finally, increasing the inspiratory positive airway pressure or decreasing the expiatory positive airway pressure of the SC ventilator can improve the efficiency of the secretion clearance. This paper lays a foundation for the secretion clearance improvement of the SC ventilator. | SHI Yan NIU JingLong CAO ZhiXin CAI MaoLin ZHU Jian | 2015 | Science China(Technological Sciences)2015，58，6： | 3 |
| 4 | The Origin of the 2008 Wenchuan Earthquake Determined by the Analysis on the Active Longmenshan Nappe in Terms of Rockmass Mechanics显示文摘On 12 May 2008, the magnitude 8.0 Wenchuan Earthquake occurred along the Longmen Shan nappe, Sichuan, China. This devastating earthquake led to a heavy death toll of greater than 80,000. The seismic origin of this earthquake is currently hotly debated. We suppose that it is a special type of intraplate earthquake called an active-nappe-type earthquake. Using a holistic methodology, incorporating rockmass structure cybernetics and Byerlee's law, we present a comprehensive study on the geological origin of macroseisms in the Longmen Shan area and the seismic origin of the 2008 Wenchuan earthquake. Previous studies of neotectonic activity indicate that the Longmen Shan nappe moves at a rate of 1~3 mm/yr, due to horizontal compressive stress from the Tibetan Plateau. The difference between movement rates in the Bayankala block, Longmen Shan nappe and Sichuan Basin cause slow shear stress and strain accumulation in the Longmen Shan nappe. It is exhibited a relatively simple linear relations for the shear strength and the buried depth of the structural planes, and the detachment layer of the nappe has a higher shearing-sliding strength compared to the overlying fault planes and the underlying ductile shear belts, thus making it more prone to stick-slip deformation. Therefore, the detachment layer was the main section responsible for the Wenchuan earthquake. The initial rupture burst in the detachment layer under the Yingxiu-Beichuan fault, the rupture area nearly 1.4454 × 104 km2,encompassed the cross point of the Yingxiu and the Anxian-Guanxian faults with the detachment layer, then caused the Yingxiu-Beichuan and Anxian-Guanxian faults took an active part in this earthquake, so this earthquake might consist of three chain-like earthquake stages, totally increasing the duration of this earthquake an unusually large amount, to 120 s. The focal depth spanned range of 10-20km,consistent with the observed result of this focal depth by several agencies. | YAN Zhixin MA Guozhe YUAN Binxiang NIU Fujun | 2012 | Journal of Mountain Science2012，9，3： | 2 |
| 5 | LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation显示文摘Idiopathic pulmonary fibrosis(IPF)is a progressive disease with unknown etiology and limited therapeutic options.Activation of fibroblasts is a prominent feature of pulmonary fibrosis.Here we report that lncRNA DACH1(dachshund homolog 1)is downregulated in the lungs of IPF patients and in an experimental mouse model of lung fibrosis.LncDACH1 knockout mice develop spontaneous pulmonary fibrosis,whereas overexpression of LncDACH1 attenuated TGF-β1-induced aberrant activation,collagen deposition and differentiation of mouse lung fibroblasts.Similarly,forced expression of LncDACH1 not only prevented bleomycin(BLM)-induced lung fibrosis,but also reversed established lung fibrosis in a BLM model.Mechanistically,LncDACH1 binding to the serine/arginine-rich splicing factor 1(SRSF1)protein decreases its activity and inhibits the accumulation of Ctnnb1.Enhanced expression of SRSF1 blocked the anti-fibrotic effect of LncDACH1 in lung fibroblasts.Furthermore,loss of LncDACH1 promoted proliferation,differentiation,and extracellular matrix(ECM)deposition in mouse lung fibroblasts,whereas such effects were abolished by silencing of Ctnnb1.In addition,a conserved fragment of LncDACH1 alleviated hyperproliferation,ECM deposition and differentiation of MRC-5 cells driven by TGF-β1.Collectively,LncDACH1 inhibits lung fibrosis by interacting with SRSF1 to suppress CTNNB1 accumulation,suggesting that LncDACH1 might be a potential therapeutic target for pulmonary fibrosis. | Jian Sun Tongzhu Jin Zhihui Niu Jiayu Guo Yingying Guo Ruoxuan Yang Qianqian Wang Huiying Gao Yuhan Zhang Tianyu Li Wenxin He Zhixin Li Wenchao Ma Wei Su Liangliang Li Xingxing Fan Hongli Shan Haihai Liang | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 1 |
| 6 | Effects of amendments of N,P,Fe on phytoextraetion of Cd,Pb,Cu,and Zn in soil of zhangshi by mustard,cabbage,and sugar beet 显示文摘 | SUN LINA NIU ZHIXIN SUN TIEHENG | 2007 | Environmental Toxicology2007，22，6： | 1 |
| 7 | A review on the emerging resilient and multifunctional ceramic aerogels显示文摘Ceramic aerogels are attractive for their low density,high porosity,large surface area as well as various applications in areas of thermal insulation,catalysis,filtration,and lightweight structural materials.Conventional ceramic aerogels are usually assembled by oxides nanoparticles.Due to the inefficient necklike connections between the nanoparticles and the volume shrinkage at elevated temperatures,ceramic aerogels fail easily caused by the brittleness and high-temperature structural collapse.To overcome these drawbacks,a class of resilient ceramic aerogels with highly porous architectures that are composed of one-or two-dimensional nanostructures has been prepared.Benefiting from the unique microstructures and/or the high-temperature stability of their building blocks,these aerogels exhibit reversible compressibility,high-temperature stability,thermal insulation,and various functions.In this review,we introduced the preparation methods,microstructures,mechanical properties,high-temperature stability,thermal insulation and various functions of these resilient ceramic aerogels.We have also discussed the relationships between their microstructures and properties,including mechanical properties and thermal insulation performance.Finally,perspectives for the further development of resilient ceramic aerogels are presented. | Lei Su Min Niu De Lu Zhixin Cai Mingzhu Li Hongjie Wang | 2021 | Journal of Materials Science & Technology2021，，16： | 1 |
| 8 | STOCHASTIC MODEL OF PERIODIC OPERATION PERFORMANCE FOR THE CONTINUOUS COUNTER-CURRENT ADSORPTION PROCESS显示文摘STOCHASTICMODELOFPERIODICOPERATIONPERFORMANCEFORTHECONTINUOUSCOUNTER-CURRENTADSORPTIONPROCESSSunShuyu(ChemicalEngineeringRese... | Sun Shuyu (Chemical Engineering Research Center, Tianjin University, Tianjin 300072 )Niu Wengtai Jiang Zhixin (Department of Chemical Engineering, Tianjin University, Tianjin 300072) | 1995 | Chinese Journal of Reactive Polymers1995，4，1： | 0 |
| 9 | Bifunctional SiC/Si_(3)N_(4) aerogel for highly efficient electromagnetic wave absorption and thermal insulation显示文摘SiC ceramics are attractive electromagnetic(EM)absorption materials for the application in harsh environment because of their low density,good dielectric tunable performance,and chemical stability.However,the performance of current SiC-based materials to absorb EM wave is generally unsatisfactory due to poor impedance matching.Herein,we report ultralight SiC/Si3N4 composite aerogels(~15 mg·cm^(−3))consisting of numerous interweaving SiC nanowires and Si3N4 nanoribbons.Aerogels were prepared via siloxane pyrolysis and chemical vapor reaction through the template method.The optimal aerogel exhibits excellent EM wave absorption properties with a strong reflection loss(RL,−48.6 dB)and a wide effective absorption band(EAB,7.4 GHz)at a thickness of 2 mm,attributed to good impedance matching and multi attenuation mechanisms of waves within the unique network structure.In addition,the aerogel exhibits high thermal stability in air until 1000℃and excellent thermal insulation performance(0.030 W·m^(−1)·K^(−1)).These superior performances make the SiC/Si_(3)N_(4) composite aerogel promising to become a new generation of absorption material served under extreme conditions. | Lei WANG Zhixin CAI Lei SU Min NIU Kang PENG Lei ZHUANG Hongjie WANG | 2023 | Journal of Advanced Ceramics2023，12，2： | 0 |
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